Research Use Only

    This site is an independent educational resource for research compounds. We do not sell, distribute, or endorse human consumption of any compound. By entering, you confirm you are 21 years of age or older and agree to our Terms & Privacy Policy.

    🔬 93K+ researchers trust BodyHackGuide — Join r/BodyHackGuide
    Growth Hormone / IGF-1 AxisPhase II

    MK-677 (Ibutamoren) Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about MK-677 (Ibutamoren) dosing — protocols, safety, and where to buy.

    Dose Range

    10,000–25,000 mcg (10–25 mg) oral daily

    Frequency

    Once daily, typically at bedtime

    Cycle Length

    8–16 weeks; some use long-term (6+ months) with monitoring

    Half-Life

    4–6 hours (effects on GH last ~24 hours due to IGF-1 elevation)

    Administration Routes

    Oral

    Dosage Calculator

    Calculate exact dosing for MK-677 (Ibutamoren).

    Dosing Protocols

    Beginner
    10 mg oral once daily at bedtime for 8 weeks. Monitor appetite and fasting glucose.
    Standard
    15–20 mg oral daily at bedtime for 12 weeks. Monitor IGF-1, fasting glucose, and HbA1c.
    Advanced
    25 mg daily for 16 weeks, can be combined with CJC-1295/Ipamorelin injections for maximal GH output. Requires glucose monitoring.

    Weight-Based Dosing

    Not weight-based. Standard doses of 10–25 mg.

    Commonly Stacked With

    Stacks well with GHK-Cu for anti-aging. Some researchers combine with BPC-157 for recovery. Avoid stacking with other GH secretagogues to prevent cortisol and insulin resistance issues.

    Side Effects & Safety

    Increased appetite (significant), water retention and bloating, numbness/tingling in extremities (paresthesia), joint pain and stiffness, elevated blood glucose and insulin resistance, mild lethargy, vivid dreams. Long-term: potential HbA1c elevation, concerns about prolonged GH elevation.

    Contraindications

    Active cancer or history of cancer. Diabetes or pre-diabetes (worsens insulin resistance). History of pituitary tumors. Intracranial hypertension. Pregnancy or breastfeeding. Children with open growth plates (unless under medical supervision).

    Check interactions with the Interaction Checker →

    Additional Notes

    Oral capsule or liquid — no injection required. Take at bedtime to align with natural GH pulse and to sleep through the hunger spike. May significantly increase appetite (ghrelin pathway). Can cause water retention and lethargy. Monitor fasting glucose as MK-677 can impair insulin sensitivity with prolonged use.

    Where to Buy MK-677 (Ibutamoren)

    Compare 1 listing across 1 vendor — from $49.99

    Frequently Asked Questions

    What is the recommended MK-677 (Ibutamoren) dosage?

    The typical dose range for MK-677 (Ibutamoren) is 10,000–25,000 mcg (10–25 mg) oral daily. It is usually administered Once daily, typically at bedtime. Always start with the lowest effective dose.

    How often should I take MK-677 (Ibutamoren)?

    Once daily, typically at bedtime

    Does MK-677 (Ibutamoren) need to be cycled?

    Yes, typical cycle length is 8–16 weeks; some use long-term (6+ months) with monitoring.

    What are MK-677 (Ibutamoren) side effects?

    Increased appetite (significant), water retention and bloating, numbness/tingling in extremities (paresthesia), joint pain and stiffness, elevated blood glucose and insulin resistance, mild lethargy, vivid dreams. Long-term: potential HbA1c elevation, concerns about prolonged GH elevation.

    Where can I buy MK-677 (Ibutamoren)?

    Compare 1 listings from 1 vendor on our price comparison page — starting from $49.99.

    MK-677 (Ibutamoren) Full Profile

    Research data, mechanisms, and pricing

    Interaction Checker

    Check drug & compound interactions

    Related Dosage Guides

    All Guides