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    NAD+ molecular structure

    NAD+

    LongevityPhase II

    Also known as: NAD Plus, Nicotinamide Adenine Dinucleotide, NAD

    An essential cellular coenzyme critical for energy metabolism, DNA repair, sirtuin activation, and healthy aging..

    Half-Life: ~1–2 hours IV; subcutaneous absorption extends effective windowRoute: Subcutaneous, Intramuscular, Intravenous, Oral (precursors)MW: 663.4 DaCAS: 53-84-975092 PubMed-Verified Studies

    Overview

    Best Price Available

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    Optimum Formula

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    Key Takeaways

    • →Enhanced cellular energy production
    • →DNA repair support
    • →Anti-aging and longevity benefits
    • →Half-life: ~1–2 hours IV; subcutaneous absorption extends effective window

    At A Glance

    Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme in all living cells. It serves as a critical substrate for sirtuins (SIRT1-7, longevity-regulating enzymes), PARPs (DNA repair), and CD38 (immune regulation). NAD+ levels naturally decline 50%+ with aging. Supplementation restores cellular energy metabolism, enhances DNA repair capacity, improves mitochondrial function, and supports circadian rhythm regulation.

    Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme in all living cells. It serves as a critical substrate for sirtuins (SIRT1-7, longevity-regulating enzymes), PARPs (DNA repair), and CD38 (immune regulation). NAD+ levels naturally decline 50%+ with aging. Supplementation restores cellular energy metabolism, enhances DNA repair capacity, improves mitochondrial function, and supports circadian rhythm regulation.

    Overview

    An essential cellular coenzyme critical for energy metabolism, DNA repair, sirtuin activation, and healthy aging.

    Potential Benefits

    Enhanced cellular energy productionDNA repair supportAnti-aging and longevity benefitsImproved mitochondrial functionNeuroprotective effectsImproved metabolic health

    Chemical Information

    IUPAC Name

    Not yet available

    CAS Number

    53-84-9

    Molecular Formula

    C21H27N7O14P2

    Molecular Mass

    663.42 g/mol

    Dosing & Protocols

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    Research

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    Interactions

    Interaction Matrix

    Contraindications

    Active cancer (NAD+ supports rapidly dividing cells). Severe liver or kidney disease. Bipolar disorder (may trigger mania). Pregnancy or breastfeeding.

    Research Disclaimer

    This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.

    Best Price

    $29.99

    up to $85.00

    Best $/mg

    $0.1100

    Vendors

    5

    Listings

    5

    strip, vial

    Dosage
    Form
    Sort
    Vendor Product Form Qty Price $/mg Coupon
    GetMelts logo
    GetMelts
    50
    🇺🇸US🌍Intl
    		 NAD Dissolving Strips strip 1 pack● In Stock $29.99BEST $5.998 —
    Optimum Formula logo
    Optimum Formula
    100
    🇺🇸US🌍Intl
    		 NAD+ 500mg vial 1 vial● In Stock $54.99VALUE $0.110
    Modern Aminos logo
    Modern Aminos
    70
    🇺🇸US🌍Intl
    		 NAD+ 500mg vial 1 vial● In Stock $54.99 $0.110
    ResearchChemHQ logo
    ResearchChemHQ
    100
    🇺🇸US🌍Intl
    		 NAD+ 500mg vial 1 vial● In Stock $54.99 $0.110
    NAD+ 500mg Vial vial 1 vial● In Stock $85.00 $0.170

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    Price History

    2 data points

    Best Price

    Optimum Formula logo

    Optimum Formula

    $54.99

    5 vendors · 5 listings

    Research Score

    70

    75092 PubMed studies

    Quality Indicators

    Data Completeness

    100%
    Description
    Mechanism of Action
    Chemical Data
    Dosing Protocols
    Safety Profile
    PubMed Studies
    Interactions
    Vendor Listings

    COA Verification

    10

    Verified COAs

    2

    Vendors w/ COA

    High verification rate (83%)

    Latest test: 3/1/2026

    Research Credibility

    75092PubMed studies

    Well-researched compound

    Quick Facts

    Half-Life

    ~1–2 hours IV; subcutaneous absorption extends effective window

    Molecular Weight

    663.42 g/mol

    Administration

    Subcutaneous, Intramuscular, Intravenous, Oral (precursors)

    CAS Number

    53-84-9

    Trial Phase

    Phase II

    Research Disclaimer

    This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.

    Frequently Asked Questions

    What is NAD+ used for in research?

    An essential cellular coenzyme critical for energy metabolism, DNA repair, sirtuin activation, and healthy aging.

    What forms does NAD+ come in?

    NAD+ is available in strip, vial forms.

    How much does NAD+ cost?

    Prices start at $29.99 across 5 verified vendors.

    How do I compare NAD+ vendors?

    Compare prices, payment methods, shipping, and COA scores across 5 vendors.

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