LL-37 vs Thymosin Alpha-1 (TA1)
Independent, side-by-side comparison of LL-37 and Thymosin Alpha-1 (TA1): mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land.
Live price snapshot
LL-37
Thymosin Alpha-1 (TA1)
LL-37
LL-37 is the only human cathelicidin, a 37-amino-acid amphipathic alpha-helical peptide (LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES) cleaved from the C-terminus of the 170-amino-acid precursor hCAP-18 (human cationic…
Live lowest price: $45.00 across 1 vendor
Full LL-37 profileThymosin Alpha-1 (TA1)
Thymosin alpha-1 (T╬▒1) is a 28-amino-acid N-acetylated peptide (N-Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn) isolated and characterized by Allan…
Live lowest price: $39.99 across 5 vendors
Full Thymosin Alpha-1 (TA1) profileSide-by-side comparison
| Attribute | LL-37 | Thymosin Alpha-1 (TA1) |
|---|---|---|
| Category | Immune & Inflammation | Immune & Inflammation |
| Research Stage | Preclinical | Approved (International) |
| Mechanism of Action | LL-37's biological activity spans three functional categories: direct antimicrobial, immunomodulatory, and tissue-remodeling. Each operates through partially distinct mechanisms. Direct Antimicrobial Mechanism (Membrane Disruption): LL-37 is a cationic… | Thymosin alpha-1 does not act through a single canonical receptor in the way many peptides do. Its mechanism is pleiotropic, involving pattern-recognition receptors, modulation of immune cell maturation and function, and shifts in cytokine signaling patterns.… |
| Half-Life | — | ~2 hours |
| Typical Dose Range | — | 1,600 mcg (1.6 mg) per injection (standard clinical dose) |
| Dosing Frequency | — | 2–3 times per week subcutaneous |
| Administration | — | Subcutaneous |
| Side Effects | LL-37 has a less benign side-effect profile than many peptides covered in this guide, reflecting its mechanistic potency and narrow therapeutic window. Common (injection site): - Injection site irritation — more pronounced than with most peptides. Redness,… | T╬▒1 has one of the most benign side-effect profiles in the peptide space, supported by 45+ years of clinical experience in approved indications. Most users experience no acute side effects beyond mild injection site discomfort. Common (5-15% of users): -… |
| Molecular Weight | 4493.4 g/mol | 3108 Da |
| Common Vial Sizes | — | 5mg, 10mg |
Price History
2 data points- VANDL Labs
- Ion Peptide
Price History
3 data points- OF
- VANDL Labs
- Ion Peptide
LL-37 — potential benefits
- Broad-spectrum antimicrobial activity
- Wound healing acceleration
- Biofilm disruption
- Immune system modulation
- Anti-inflammatory effects
- Gut barrier support
Thymosin Alpha-1 (TA1) — potential benefits
- Immune enhancement
- Antiviral defense
- Cancer adjuvant therapy
- Autoimmune modulation
- Vaccine potentiation
Frequently asked
What's the difference between LL-37 and Thymosin Alpha-1 (TA1)?
LL-37 is a immune & inflammation that ll-37's biological activity spans three functional categories: direct antimicrobial, immunomodulatory, and tissue-remodeling. each operates through partially distinct mechanisms.…. Thymosin Alpha-1 (TA1) is a immune & inflammation that thymosin alpha-1 does not act through a single canonical receptor in the way many peptides do. its mechanism is pleiotropic, involving pattern-recognition receptors, modulation of…. The two differ in mechanism, half-life (not reported vs ~2 hours), and typical dose range.
Which has the longer half-life, LL-37 or Thymosin Alpha-1 (TA1)?
LL-37 has a half-life of not reported. Thymosin Alpha-1 (TA1) has a half-life of ~2 hours. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, LL-37 or Thymosin Alpha-1 (TA1)?
Current lowest live price on BodyHackGuide: LL-37 from $45.00, Thymosin Alpha-1 (TA1) from $39.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers.
Can you stack LL-37 and Thymosin Alpha-1 (TA1)?
Stacking depends on mechanism overlap, safety profile, and goals. LL-37 and Thymosin Alpha-1 (TA1) should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Research use only. BodyHackGuide is an independent research reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks — this never affects the data or pricing shown. See editorial standards and affiliate disclosure.