Hexarelin vs Ipamorelin
Independent, side-by-side comparison of Hexarelin and Ipamorelin: mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land.
Live price snapshot
Hexarelin
Ipamorelin
Hexarelin
Hexarelin (also called examorelin) is a potent synthetic hexapeptide growth hormone secretagogue with the sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2. It is structurally similar to GHRP-6 and GHRP-2 but features a…
Full Hexarelin profileIpamorelin
Ipamorelin is a selective pentapeptide ghrelin receptor (GHS-R1a) agonist — one of the most studied growth hormone secretagogues (GHS) in the biohacking community and the modern companion to CJC-1295 / MOD-GRF 1-29. Its…
Live lowest price: $24.99 across 4 vendors
Full Ipamorelin profileSide-by-side comparison
| Attribute | Hexarelin | Ipamorelin |
|---|---|---|
| Category | Growth Hormone / IGF-1 Axis | Growth Hormone / IGF-1 Axis |
| Research Stage | Phase II | Phase 2 |
| Mechanism of Action | Dual Receptor Pharmacology Hexarelin is distinguished from other GHRPs by its activity at two distinct receptors: GHS-R1a (primary — GH release) Like all GHRPs, hexarelin binds the ghrelin receptor (GHS-R1a) on pituitary somatotrophs and hypothalamic neurons:… | Ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (GHS-R1a), the same receptor activated by endogenous ghrelin — the "hunger hormone" secreted primarily by P/D1 cells in the gastric fundus. The distinguishing feature of… |
| Half-Life | ~70 minutes | ~2 hours (plasma) |
| Typical Dose Range | 100–200 mcg per injection | 100-300 mcg subcutaneous 1-3x daily (most commonly 200-300 mcg pre-bedtime); often combined with CJC-1295 without DAC at 100-300 mcg |
| Dosing Frequency | 1–2 times daily; subject to desensitization within 4 weeks | 1–3 times daily; most commonly once at bedtime |
| Administration | Subcutaneous, Intramuscular | subcutaneous, intravenous (clinical only) |
| Side Effects | Common - Facial flushing and warmth — More pronounced than other GHRPs due to potency. Fades within 15-30 minutes. - Injection site reactions — Mild erythema, occasional stinging at SC site. Site rotation minimizes. - Cortisol elevation (+30-50% above… | Ipamorelin has the cleanest side-effect profile of any ghrelin-receptor agonist, which is why it dominates modern biohacking protocols. The profile is driven by (a) selective GHS-R1a agonism without cross-receptor activity, and (b) acute GH elevation (the same… |
| Molecular Weight | 887 Da | 711.9 Da |
| Common Vial Sizes | 2mg, 5mg | 2mg, 5mg |
Price tracking
Price History
3 data points- OF
- VANDL Labs
- Ion Peptide
Hexarelin — potential benefits
- Maximum GH output
- Cardiac protection
- Muscle building
- Body composition
- Recovery
Ipamorelin — potential benefits
- Increased GH pulse amplitude (selective somatotroph activation)
- Elevated IGF-1 (~30-80% over baseline) with consistent dosing
- Improved slow-wave sleep architecture
- No cortisol / prolactin / ACTH elevation (unique among GHS peptides)
- Accelerated connective tissue and wound repair
- Modest lean body mass gain + fat loss in hypogonadal adults
- Enhanced recovery between training sessions
- Synergistic effect with CJC-1295 / MOD-GRF 1-29
Frequently asked
What's the difference between Hexarelin and Ipamorelin?
Hexarelin is a growth hormone / igf-1 axis that dual receptor pharmacology hexarelin is distinguished from other ghrps by its activity at two distinct receptors: ghs-r1a (primary — gh release) like all ghrps, hexarelin binds the…. Ipamorelin is a growth hormone / igf-1 axis that ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (ghs-r1a), the same receptor activated by endogenous ghrelin — the "hunger hormone" secreted…. The two differ in mechanism, half-life (~70 minutes vs ~2 hours (plasma)), and typical dose range.
Which has the longer half-life, Hexarelin or Ipamorelin?
Hexarelin has a half-life of ~70 minutes. Ipamorelin has a half-life of ~2 hours (plasma). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Hexarelin and Ipamorelin?
Stacking depends on mechanism overlap, safety profile, and goals. Hexarelin and Ipamorelin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Live listings from the vendors we track, refreshed continuously.
Related comparisons
Research use only. BodyHackGuide is an independent research reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks — this never affects the data or pricing shown. See editorial standards and affiliate disclosure.