GHRP-2 vs Ipamorelin
Independent, side-by-side comparison of GHRP-2 and Ipamorelin: mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land.
Live price snapshot
GHRP-2
Ipamorelin
GHRP-2
GHRP-2 (growth hormone-releasing peptide-2), also known as pralmorelin and KP-102, is a synthetic hexapeptide growth hormone secretagogue that was among the first GHRPs developed in the seminal research of Cyril Bowers…
Live lowest price: $29.00 across 2 vendors
Full GHRP-2 profileIpamorelin
Ipamorelin is a selective pentapeptide ghrelin receptor (GHS-R1a) agonist — one of the most studied growth hormone secretagogues (GHS) in the biohacking community and the modern companion to CJC-1295 / MOD-GRF 1-29. Its…
Live lowest price: $24.99 across 4 vendors
Full Ipamorelin profileSide-by-side comparison
| Attribute | GHRP-2 | Ipamorelin |
|---|---|---|
| Category | Growth Hormone / IGF-1 Axis | Growth Hormone / IGF-1 Axis |
| Research Stage | Phase II | Phase 2 |
| Mechanism of Action | GHS-R1a Receptor Agonism GHRP-2 binds the growth hormone secretagogue receptor type 1a (GHS-R1a), the endogenous target of ghrelin, with nanomolar affinity. GHS-R1a is expressed on: - Anterior pituitary somatotrophs — direct GH release - Hypothalamic arcuate… | Ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (GHS-R1a), the same receptor activated by endogenous ghrelin — the "hunger hormone" secreted primarily by P/D1 cells in the gastric fundus. The distinguishing feature of… |
| Half-Life | ~1 hour | ~2 hours (plasma) |
| Typical Dose Range | 100–300 mcg per injection | 100-300 mcg subcutaneous 1-3x daily (most commonly 200-300 mcg pre-bedtime); often combined with CJC-1295 without DAC at 100-300 mcg |
| Dosing Frequency | 1–3 times daily; bedtime injection most important | 1–3 times daily; most commonly once at bedtime |
| Administration | Subcutaneous, Intramuscular, Intranasal | subcutaneous, intravenous (clinical only) |
| Side Effects | Common (dose-dependent) - Increased appetite / hunger — GHRP-2 is a ghrelin-receptor agonist, and ghrelin is the body's primary hunger signal. Expect measurable appetite stimulation starting ~30 minutes post-injection and peaking at 1-2 hours. Beneficial in… | Ipamorelin has the cleanest side-effect profile of any ghrelin-receptor agonist, which is why it dominates modern biohacking protocols. The profile is driven by (a) selective GHS-R1a agonism without cross-receptor activity, and (b) acute GH elevation (the same… |
| Molecular Weight | 817.9 Da | 711.9 Da |
| Common Vial Sizes | 5mg, 10mg | 2mg, 5mg |
Price History
2 data points- VANDL Labs
- Ion Peptide
Price History
3 data points- OF
- VANDL Labs
- Ion Peptide
GHRP-2 — potential benefits
- High GH output
- Muscle building
- Fat loss
- Recovery
- Appetite stimulation
- Anti-aging
Ipamorelin — potential benefits
- Increased GH pulse amplitude (selective somatotroph activation)
- Elevated IGF-1 (~30-80% over baseline) with consistent dosing
- Improved slow-wave sleep architecture
- No cortisol / prolactin / ACTH elevation (unique among GHS peptides)
- Accelerated connective tissue and wound repair
- Modest lean body mass gain + fat loss in hypogonadal adults
- Enhanced recovery between training sessions
- Synergistic effect with CJC-1295 / MOD-GRF 1-29
Frequently asked
What's the difference between GHRP-2 and Ipamorelin?
GHRP-2 is a growth hormone / igf-1 axis that ghs-r1a receptor agonism ghrp-2 binds the growth hormone secretagogue receptor type 1a (ghs-r1a), the endogenous target of ghrelin, with nanomolar affinity. ghs-r1a is expressed…. Ipamorelin is a growth hormone / igf-1 axis that ipamorelin acts as a selective agonist at the growth hormone secretagogue receptor 1a (ghs-r1a), the same receptor activated by endogenous ghrelin — the "hunger hormone" secreted…. The two differ in mechanism, half-life (~1 hour vs ~2 hours (plasma)), and typical dose range.
Which has the longer half-life, GHRP-2 or Ipamorelin?
GHRP-2 has a half-life of ~1 hour. Ipamorelin has a half-life of ~2 hours (plasma). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, GHRP-2 or Ipamorelin?
Current lowest live price on BodyHackGuide: GHRP-2 from $29.00, Ipamorelin from $24.99. Prices are pulled from the vendor listings tracked on BHG and change frequently — see the compare tables on each compound page for the current set of offers.
Can you stack GHRP-2 and Ipamorelin?
Stacking depends on mechanism overlap, safety profile, and goals. GHRP-2 and Ipamorelin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Research use only. BodyHackGuide is an independent research reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks — this never affects the data or pricing shown. See editorial standards and affiliate disclosure.