Skip to content
    Compare notes on r/BodyHackGuideCompare notes with other researchers. Join r/BodyHackGuide
    Anabolic PeptidePreclinical / Research peptide

    MGF (Mechano Growth Factor) Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about MGF (Mechano Growth Factor) dosing: protocols and safety.

    Dose Range

    100-300 mcg (PEG-MGF)

    Frequency

    Twice per week post-workout

    Cycle Length

    4-6 weeks per cycle, 4 weeks off

    Half-Life

    Reported/estimated only; no published human PK data. Commonly cited community figures are ~5-7 minutes for native MGF and ~24-48 hours for PEGylated PEG-MGF; neither has been established in human pharmacokinetic studies.

    Administration Routes

    SubcutaneousIntramuscular

    Quick Reconstitution Calculator

    Calculate syringe units instantly

    Syringe Draw

    10.0 units

    2500 mcg/ml · 0.100 ml draw

    Full Tool

    For laboratory research use only. This tool performs reconstitution math (concentration and syringe-unit conversion) and is not dosing guidance for humans or animals.

    Dosing Protocols

    Beginner

    100 mcg PEG-MGF intramuscular post-workout, 2x per week, for 4 weeks.

    Standard

    200 mcg PEG-MGF, 2-3x per week, for 6 weeks. Pair with creatine + protein for synergy.

    Advanced

    300 mcg PEG-MGF intramuscular at injury or hypertrophy target site, 3x per week, for 4-6 weeks.

    Commonly Stacked With

    Common stacking: post-workout intramuscular MGF + BPC-157 for tendon repair + TB-500 for systemic recovery. Pair with CJC-1295 for downstream IGF-1 amplification - though stacking growth-factor peptides at high dose has theoretical malignancy concerns.

    Side Effects & Safety

    Limited safety data. Anecdotal AEs include: injection site soreness, transient hypoglycemia (related to IGF activity), water retention. Theoretical concerns: any pre-existing malignancy due to growth-factor activity.

    Contraindications

    Active malignancy or cancer history (relative). Pregnancy and breastfeeding. Active diabetic ketoacidosis. Caution with concurrent IGF-1 LR3 - overlapping growth-factor activity.

    Check interactions with the Interaction Checker →

    Additional Notes

    Native MGF vs PEG-MGF: native is typically injected immediately post-workout into the trained muscle, since its half-life is estimated at only ~5-7 minutes (community estimate; no human PK data). PEG-MGF is PEGylated to circulate longer and can be dosed within hours of training. Reconstitute with bacteriostatic water; refrigerate; use within 28 days. Research use only.

    Frequently Asked Questions

    What is the recommended MGF (Mechano Growth Factor) dosage?

    The typical dose range for MGF (Mechano Growth Factor) is 100-300 mcg (PEG-MGF). It is usually administered Twice per week post-workout. Always start with the lowest effective dose.

    How often should I take MGF (Mechano Growth Factor)?

    Twice per week post-workout

    Does MGF (Mechano Growth Factor) need to be cycled?

    Yes, typical cycle length is 4-6 weeks per cycle, 4 weeks off.

    What are MGF (Mechano Growth Factor) side effects?

    Limited safety data. Anecdotal AEs include: injection site soreness, transient hypoglycemia (related to IGF activity), water retention. Theoretical concerns: any pre-existing malignancy due to growth-factor activity.

    Where can I buy MGF (Mechano Growth Factor)?

    Visit our vendor directory to compare the vendors we track and their Trust Scores.

    Free 2026 Peptide Cheat Sheet (PDF)

    38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers.

    Download Free