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    Anabolic PeptidePreclinical / Research peptide

    IGF-1 Des(1-3) Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about IGF-1 Des(1-3) dosing: protocols and safety.

    Dose Range

    20-100 mcg

    Frequency

    Once daily on training days

    Cycle Length

    4-6 weeks per cycle, 4 weeks off

    Half-Life

    ~20-30 minutes serum

    Administration Routes

    SubcutaneousIntramuscular

    Quick Reconstitution Calculator

    Calculate syringe units instantly

    Syringe Draw

    10.0 units

    2500 mcg/ml · 0.100 ml draw

    Full Tool

    For laboratory research use only. This tool performs reconstitution math (concentration and syringe-unit conversion) and is not dosing guidance for humans or animals.

    Dosing Protocols

    Beginner

    20 mcg intramuscular into trained muscle post-workout, 3-4x per week, for 4 weeks.

    Standard

    40-60 mcg intramuscular post-workout, 4-5x per week. Eat carb-rich meal within 30 min of injection to manage hypoglycemia risk.

    Advanced

    50-100 mcg site-injection post-workout, daily on training days. Advanced protocols stay within 6-week cycles.

    Commonly Stacked With

    Common in bodybuilding stacks with MGF post-workout and BPC-157 for tendon support. Pair with CJC-1295 + Ipamorelin for GH-IGF axis stacking. Avoid stacking with IGF-1 LR3 - overlapping mechanism, additive AE risk.

    Side Effects & Safety

    Anecdotal AEs: hypoglycemia (most common, requires food intake post-injection), lightheadedness, headache, injection site soreness. Theoretical: long-term IGF receptor activation has been associated in epidemiology with some cancer types.

    Contraindications

    Active malignancy or cancer history. Pregnancy and breastfeeding. Hypoglycemia-prone or fasted state. Active proliferative diabetic retinopathy.

    Check interactions with the Interaction Checker →

    Additional Notes

    Reconstitute with bacteriostatic water. A 1mg vial + 1mL BAC water = 1000 mcg/mL. 2 units = 20 mcg starting dose. ALWAYS eat within 30 minutes of injection - hypoglycemia risk is significant.

    Frequently Asked Questions

    What is the recommended IGF-1 Des(1-3) dosage?

    The typical dose range for IGF-1 Des(1-3) is 20-100 mcg. It is usually administered Once daily on training days. Always start with the lowest effective dose.

    How often should I take IGF-1 Des(1-3)?

    Once daily on training days

    Does IGF-1 Des(1-3) need to be cycled?

    Yes, typical cycle length is 4-6 weeks per cycle, 4 weeks off.

    What are IGF-1 Des(1-3) side effects?

    Anecdotal AEs: hypoglycemia (most common, requires food intake post-injection), lightheadedness, headache, injection site soreness. Theoretical: long-term IGF receptor activation has been associated in epidemiology with some cancer types.

    Where can I buy IGF-1 Des(1-3)?

    Visit our vendor directory to compare the vendors we track and their Trust Scores.

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