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    Semax molecular structure

    Semax

    NootropicApproved (Russia)

    Also known as: ACTH 4-10

    A synthetic nootropic and neuroprotective peptide derived from ACTH, studied for cognitive enhancement, stroke recovery, and focus..

    Half-Life: ~3–5 minutes IV; intranasal extends effective duration to several hoursRoute: Intranasal, SubcutaneousMW: 813.9 DaCAS: 80714-61-0204 PubMed-Verified Studies

    Overview

    Best Price Available

    Optimum Formula logo

    Optimum Formula

    $34.99

    1 vial · vial

    Coupon:REDDIT

    Key Takeaways

    • →Enhanced focus and concentration
    • →Improved memory and learning capacity
    • →Neuroprotective effects
    • →Half-life: ~3–5 minutes IV; intranasal extends effective duration to several hours

    At A Glance

    Semax is a synthetic analog of ACTH(4-7) (Met-Glu-His-Phe) with a Pro-Gly-Pro C-terminal extension for enzymatic stability. It enhances BDNF and NGF expression, modulates dopaminergic and serotonergic neurotransmission, promotes neuroplasticity, and has neuroprotective effects against oxidative stress. Does NOT activate adrenal cortisol production despite being derived from ACTH.

    Semax is a synthetic analog of ACTH(4-7) (Met-Glu-His-Phe) with a Pro-Gly-Pro C-terminal extension for enzymatic stability. It enhances BDNF and NGF expression, modulates dopaminergic and serotonergic neurotransmission, promotes neuroplasticity, and has neuroprotective effects against oxidative stress. Does NOT activate adrenal cortisol production despite being derived from ACTH.

    Overview

    A synthetic nootropic and neuroprotective peptide derived from ACTH, studied for cognitive enhancement, stroke recovery, and focus.

    Potential Benefits

    Enhanced focus and concentrationImproved memory and learning capacityNeuroprotective effectsIncreased BDNF and NGF expressionStroke recovery supportImproved cognitive performance under stress

    Chemical Information

    IUPAC Name

    Met-Glu-His-Phe-Pro-Gly-Pro

    CAS Number

    80714-61-0

    Molecular Formula

    C37H53N9O10S

    Molecular Mass

    766.94 g/mol

    Dosing & Protocols

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    Research

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    Interactions

    Interaction Matrix

    Contraindications

    Active hypertension (Semax can mildly increase BP). Mania or bipolar disorder. Pregnancy or breastfeeding.

    Research Disclaimer

    This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.

    Best Price

    $34.99

    Best $/mg

    $3.4990

    Vendors

    3

    Listings

    3

    vial

    Form
    Sort
    Vendor Product Form Qty Price $/mg Coupon
    Optimum Formula logo
    Optimum Formula
    100
    🇺🇸US🌍Intl
    		 Semax 10mg vial 1 vial● In Stock $34.99BEST $3.499
    Modern Aminos logo
    Modern Aminos
    70
    🇺🇸US🌍Intl
    		 Semax 10mg vial 1 vial● In Stock $34.99 $3.499
    ResearchChemHQ logo
    ResearchChemHQ
    100
    🇺🇸US🌍Intl
    		 Semax 10mg vial 1 vial● In Stock $34.99 $3.499

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    Set a target price and we'll notify you when any vendor drops below it. Current lowest: $34.99

    Best Price

    Optimum Formula logo

    Optimum Formula

    $34.99

    3 vendors · 3 listings

    Research Score

    50

    204 PubMed studies

    Quality Indicators

    Data Completeness

    100%
    Description
    Mechanism of Action
    Chemical Data
    Dosing Protocols
    Safety Profile
    PubMed Studies
    Interactions
    Vendor Listings

    COA Verification

    10

    Verified COAs

    2

    Vendors w/ COA

    High verification rate (83%)

    Latest test: 3/1/2026

    Research Credibility

    204PubMed studies

    Well-researched compound

    Quick Facts

    Half-Life

    ~3–5 minutes IV; intranasal extends effective duration to several hours

    Molecular Weight

    766.94 g/mol

    Administration

    Intranasal, Subcutaneous

    CAS Number

    80714-61-0

    Trial Phase

    Approved (Russia)

    Research Disclaimer

    This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.

    Frequently Asked Questions

    What is Semax used for in research?

    A synthetic nootropic and neuroprotective peptide derived from ACTH, studied for cognitive enhancement, stroke recovery, and focus.

    What forms does Semax come in?

    Semax is available in vial form.

    How much does Semax cost?

    Prices start at $34.99 across 3 verified vendors.

    How do I compare Semax vendors?

    Compare prices, payment methods, shipping, and COA scores across 3 vendors.

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