9-MBC (9-Methyl-β-carboline)
NootropicsPreclinical9-Methyl-β-carboline (9-MBC) is a synthetic β-carboline alkaloid that has gained significant interest in the nootropic community for its reported ability to promote dopaminergic neuron growth, increase dopamine synthesis enzymes, and provide neuroprotective effects against neurotoxins. It is one of the few compounds with preclinical evidence for actual dopaminergic neurogenesis rather than just release or reuptake modulation..
Overview
At A Glance
A dopaminergic and serotonergic compound that acts as both a beta-carboline alkaloid and a phosphodiesterase inhibitor. It enhances dopamine transporter expression and increases dopamine levels while also promoting neurogenesis and UV-stimulated melanogenesis.
Overview
9-Methyl-β-carboline (9-MBC) is a synthetic β-carboline alkaloid that has gained significant interest in the nootropic community for its reported ability to promote dopaminergic neuron growth, increase dopamine synthesis enzymes, and provide neuroprotective effects against neurotoxins. It is one of the few compounds with preclinical evidence for actual dopaminergic neurogenesis rather than just release or reuptake modulation.
Potential Research Fields
Chemical Information
IUPAC Name
9-methyl-9H-pyrido[3,4-b]indole
CAS Number
2521-07-5
Molecular Formula
C12H10N2
Molecular Mass
182.22 g/mol
Dosing & Protocols
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Research
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Interactions
Interaction Matrix
Contraindications
Concurrent UV/sun exposure (phototoxic — can cause DNA damage). SSRI/MAOI use. Liver disease. History of melanoma. Pregnancy or breastfeeding.
Research Disclaimer
This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.
No listings found for 9-MBC (9-Methyl-β-carboline).
Related Compounds
View AllBromantane
NootropicsRussia ApprovedBromantane is an atypical psychostimulant and anxiolytic developed in the 1980s at the Zakusov Institute of Pharmacology of the Russian Academy of Medical Sciences, originally created as an adaptogen for Soviet military and elite athletic use and later approved in Russia for the treatment of neurasthenic and asthenic disorders under the trade name Ladasten.
Dihexa
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Kavain
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L-Theanine
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L-Tyrosine
NootropicsPreclinicalL-Tyrosine is a non-essential aromatic amino acid and the direct biosynthetic precursor to the catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine.
Lion's Mane Mushroom
NootropicsPhase 2Lion's Mane (scientific name Hericium erinaceus; also known as yamabushitake in Japanese, houtou in Chinese, bearded tooth fungus, monkey head mushroom, and pom pom mushroom) is a white-to-cream coloured edible and medicinal mushroom in the tooth fungus family (Hericiaceae), characterised by its distinctive cascading spines that resemble a lion's mane or white cascading icicles.
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Protocols, calculator & safety for 9-MBC (9-Methyl-β-carboline)
Research Score
6 PubMed studies
Quality Indicators
Data Completeness
88%Research Credibility
Limited research available
Quick Facts
Molecular Weight
182.22 g/mol
CAS Number
2521-07-5
Trial Phase
Preclinical
Safety Profile
Moderate RiskCommon Side Effects
- • Light sensitivity (photosensitizer — avoid direct sun exposure for hours after dosing)
- • Overstimulation at high doses
- • Insomnia if dosed late
Stop Use If
- CRITICAL: Do NOT combine with SSRIs, SNRIs, MAOIs, MDMA, or serotonergic substances — serotonin syndrome risk
- Avoid tyramine-rich foods while using (MAO inhibition)
- Avoid UV/sunlight exposure on dosing days — phototoxicity risk
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is 9-MBC (9-Methyl-β-carboline) used for in research?
9-Methyl-β-carboline (9-MBC) is a synthetic β-carboline alkaloid that has gained significant interest in the nootropic community for its reported ability to promote dopaminergic neuron growth, increase dopamine synthesis enzymes, and provide neuroprotective effects against neurotoxins. It is one of the few compounds with preclinical evidence for actual dopaminergic neurogenesis rather than just release or reuptake modulation.
What forms does 9-MBC (9-Methyl-β-carboline) come in?
9-MBC (9-Methyl-β-carboline) is available in vials, capsules, and sprays forms.
How much does 9-MBC (9-Methyl-β-carboline) cost?
Pricing varies by vendor and form.
How do I compare 9-MBC (9-Methyl-β-carboline) vendors?
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Research Tools
Related Compounds
View AllBromantane
NootropicsRussia ApprovedBromantane is an atypical psychostimulant and anxiolytic developed in the 1980s at the Zakusov Institute of Pharmacology of the Russian Academy of Medical Sciences, originally created as an adaptogen for Soviet military and elite athletic use and later approved in Russia for the treatment of neurasthenic and asthenic disorders under the trade name Ladasten.
Dihexa
NootropicsPreclinicalDihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University.
Kavain
NootropicsPreclinicalActive compound from kava for relaxation and sleep support..
L-Theanine
NootropicsFDA ApprovedL-Theanine is a non-proteinogenic amino acid found almost exclusively in tea (Camellia sinensis) and a handful of edible mushrooms, and it has become the single most widely-used calm-focus nootropic in the modern supplement market — both on its own at 100-400mg doses and, even more prominently, as the classic 1:1 or 2:1 pair with caffeine that defines the "calm-focus" experiential signature of green tea and of virtually every serious nootropic stack.
L-Tyrosine
NootropicsPreclinicalL-Tyrosine is a non-essential aromatic amino acid and the direct biosynthetic precursor to the catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine.
Lion's Mane Mushroom
NootropicsPhase 2Lion's Mane (scientific name Hericium erinaceus; also known as yamabushitake in Japanese, houtou in Chinese, bearded tooth fungus, monkey head mushroom, and pom pom mushroom) is a white-to-cream coloured edible and medicinal mushroom in the tooth fungus family (Hericiaceae), characterised by its distinctive cascading spines that resemble a lion's mane or white cascading icicles.
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