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9-MBC (9-Methyl-β-carboline)
NootropicsPreclinical9-Methyl-β-carboline (9-MBC) is a synthetic β-carboline alkaloid that has gained significant interest in the nootropic community for its reported ability to promote dopaminergic neuron growth, increase dopamine synthesis enzymes, and provide neuroprotective effects against neurotoxins. It is one of the few compounds with preclinical evidence for actual dopaminergic neurogenesis rather than just release or reuptake modulation..
Overview
Key Takeaways
- →Enhanced dopamine levels
- →Increased motivation and drive
- →Neurogenesis promotion
At A Glance
A dopaminergic and serotonergic compound that acts as both a beta-carboline alkaloid and a phosphodiesterase inhibitor. It enhances dopamine transporter expression and increases dopamine levels while also promoting neurogenesis and UV-stimulated melanogenesis.
A dopaminergic and serotonergic compound that acts as both a beta-carboline alkaloid and a phosphodiesterase inhibitor. It enhances dopamine transporter expression and increases dopamine levels while also promoting neurogenesis and UV-stimulated melanogenesis.
Overview
9-Methyl-β-carboline (9-MBC) is a synthetic β-carboline alkaloid that has gained significant interest in the nootropic community for its reported ability to promote dopaminergic neuron growth, increase dopamine synthesis enzymes, and provide neuroprotective effects against neurotoxins. It is one of the few compounds with preclinical evidence for actual dopaminergic neurogenesis rather than just release or reuptake modulation.
Potential Benefits
Potential Research Fields
Chemical Information
IUPAC Name
9-methyl-9H-pyrido[3,4-b]indole
CAS Number
2521-07-5
Molecular Formula
C12H10N2
Molecular Mass
182.22 g/mol
Dosing & Protocols
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Research
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Interactions
Interaction Matrix
Contraindications
Concurrent UV/sun exposure (phototoxic — can cause DNA damage). SSRI/MAOI use. Liver disease. History of melanoma. Pregnancy or breastfeeding.
Research Disclaimer
This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.
No listings found for 9-MBC (9-Methyl-β-carboline).
Related Compounds
View AllAlpha-GPC
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Alpha-GPC (L-alpha glycerylphosphorylcholine) is a choline-containing phospholipid naturally present in the brain and found in small amounts in dairy and meat.
Bromantane
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Bromantane (Ladasten) is an atypical psychostimulant and anxiolytic developed in Russia, approved there for asthenia.
CDP-Choline (Citicoline)
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CDP-Choline (cytidine diphosphocholine, citicoline) is a naturally occurring nucleotide found in every cell in the body, and one of the most evidence-backed nootropics available.
Dihexa
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Lion's Mane Mushroom
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Lion's Mane (Hericium erinaceus) is a medicinal mushroom with a growing body of clinical evidence for cognitive enhancement, neurogenesis, and nerve repair.
Methylene Blue
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Mitochondrial enhancer and cognitive support compound.
View Full Dosage Guide →
Protocols, calculator & safety for 9-MBC (9-Methyl-β-carboline)
Research Score
6 PubMed studies
Quality Indicators
Data Completeness
88%Research Credibility
Limited research available
Quick Facts
Molecular Weight
182.22 g/mol
CAS Number
2521-07-5
Trial Phase
Preclinical
Safety Profile
Moderate RiskCommon Side Effects
- • Light sensitivity (photosensitizer — avoid direct sun exposure for hours after dosing)
- • Overstimulation at high doses
- • Insomnia if dosed late
Stop Use If
- CRITICAL: Do NOT combine with SSRIs, SNRIs, MAOIs, MDMA, or serotonergic substances — serotonin syndrome risk
- Avoid tyramine-rich foods while using (MAO inhibition)
- Avoid UV/sunlight exposure on dosing days — phototoxicity risk
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is 9-MBC (9-Methyl-β-carboline) used for in research?
9-Methyl-β-carboline (9-MBC) is a synthetic β-carboline alkaloid that has gained significant interest in the nootropic community for its reported ability to promote dopaminergic neuron growth, increase dopamine synthesis enzymes, and provide neuroprotective effects against neurotoxins. It is one of the few compounds with preclinical evidence for actual dopaminergic neurogenesis rather than just release or reuptake modulation.
What forms does 9-MBC (9-Methyl-β-carboline) come in?
9-MBC (9-Methyl-β-carboline) is available in vials, capsules, and sprays forms.
How much does 9-MBC (9-Methyl-β-carboline) cost?
Pricing varies by vendor and form.
How do I compare 9-MBC (9-Methyl-β-carboline) vendors?
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Research Tools
Related Compounds
View AllAlpha-GPC
Nootropics
Alpha-GPC (L-alpha glycerylphosphorylcholine) is a choline-containing phospholipid naturally present in the brain and found in small amounts in dairy and meat.
Bromantane
Nootropics
Bromantane (Ladasten) is an atypical psychostimulant and anxiolytic developed in Russia, approved there for asthenia.
CDP-Choline (Citicoline)
Nootropics
CDP-Choline (cytidine diphosphocholine, citicoline) is a naturally occurring nucleotide found in every cell in the body, and one of the most evidence-backed nootropics available.
Dihexa
Nootropics
Dihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University.
Lion's Mane Mushroom
Nootropics
Lion's Mane (Hericium erinaceus) is a medicinal mushroom with a growing body of clinical evidence for cognitive enhancement, neurogenesis, and nerve repair.
Methylene Blue
Nootropics
Mitochondrial enhancer and cognitive support compound.