Skip to content
    Compare notes on r/BodyHackGuideCompare notes with other researchers. Join r/BodyHackGuide
    PerformancePhase 1

    RAD-140 (Testolone) Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about RAD-140 (Testolone) dosing: protocols, safety, and where to buy.

    Half-Life

    Terminal half-life 44.7 hours in humans, measured in a first-in-human phase 1 study in postmenopausal women with metastatic breast cancer (PMID: 34565686)

    Administration Routes

    Oral

    Dosage Calculator

    Calculate exact dosing for RAD-140 (Testolone).

    Dosing data for RAD-140 (Testolone) is being researched. Check the compound page for the latest information.

    Side Effects & Safety

    In the phase 1 study of 22 patients, treatment-emergent adverse events included raised aspartate aminotransferase in 59.1 percent, raised alanine aminotransferase in 45.5 percent, raised total bilirubin in 27.3 percent, and vomiting, dehydration, reduced appetite and weight loss in 27.3 percent each; grade 3 or 4 events occurred in 16 of 22 patients (PMID: 34565686). Published case reports outside trials describe biopsy-confirmed cholestatic liver injury with prolonged jaundice after RAD-140 use (PMID: 36561105, PMID: 36945289, PMID: 39328701, PMID: 36978171, PMID: 38444893), one case of bile cast nephropathy and kidney injury needing plasmapheresis in a man who had used three different SARMs (PMID: 37501938), and cardiac events including acute myocarditis (PMID: 35233331), myopericarditis in an adolescent (PMID: 39157568) and heart failure (PMID: 38864168). In female mice, long-term RAD140 raised frailty and mortality risk (PMID: 37758180).

    Contraindications

    Mechanism-based: contraindicated in pregnancy, since androgen receptor agonists can virilize a female fetus, and in men with known or suspected prostate cancer. Pre-existing liver disease or raised transaminases is both mechanism-based and case-report-based, given how frequently transaminase and bilirubin rises appeared in the phase 1 trial and in published liver injury reports (PMID: 34565686, PMID: 36945289). Cardiac case reports, including one in a 16-year-old, are a reason to avoid it in anyone with known cardiac disease (PMID: 39157568, PMID: 38864168). Prohibited in tested sport at all times (PMID: 28137616).

    Check interactions with the Interaction Checker →

    Frequently Asked Questions

    What is the recommended RAD-140 (Testolone) dosage?

    Dosage for RAD-140 (Testolone) varies by protocol. Consult a qualified healthcare provider.

    How often should I take RAD-140 (Testolone)?

    Administration frequency depends on the specific protocol. Consult current research literature.

    Does RAD-140 (Testolone) need to be cycled?

    Cycling requirements depend on the protocol. Follow established research guidelines.

    What are RAD-140 (Testolone) side effects?

    In the phase 1 study of 22 patients, treatment-emergent adverse events included raised aspartate aminotransferase in 59.1 percent, raised alanine aminotransferase in 45.5 percent, raised total bilirubin in 27.3 percent, and vomiting, dehydration, reduced appetite and weight loss in 27.3 percent each; grade 3 or 4 events occurred in 16 of 22 patients (PMID: 34565686). Published case reports outside trials describe biopsy-confirmed cholestatic liver injury with prolonged jaundice after RAD-140 use (PMID: 36561105, PMID: 36945289, PMID: 39328701, PMID: 36978171, PMID: 38444893), one case of bile cast nephropathy and kidney injury needing plasmapheresis in a man who had used three different SARMs (PMID: 37501938), and cardiac events including acute myocarditis (PMID: 35233331), myopericarditis in an adolescent (PMID: 39157568) and heart failure (PMID: 38864168). In female mice, long-term RAD140 raised frailty and mortality risk (PMID: 37758180).

    Where can I buy RAD-140 (Testolone)?

    Compare 1 listings from 1 vendor on our price comparison page, starting from $84.99.

    Free 2026 Peptide Cheat Sheet (PDF)

    38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers.

    Download Free