Melanotan-1 Dosage Guide: Protocols, Calculator & Safety
Everything you need to know about Melanotan-1 dosing — protocols, safety, and where to buy.
Dose Range
500-1000 mcg loading; 500 mcg maintenance
Frequency
Daily during loading (2-4 weeks); weekly maintenance after
Cycle Length
2-4 weeks loading, then weekly maintenance dosing
Half-Life
~30 minutes serum (subcutaneous absorption is the rate-limiter for clinical use)
Administration Routes
Quick Reconstitution Calculator
Calculate syringe units instantly
Syringe Draw
10.0 units
2500 mcg/ml · 0.100 ml draw
Dosing Protocols
500 mcg subcutaneous daily for 2 weeks (loading). Pair with mild UV exposure to drive tanning. Then drop to weekly maintenance at 500 mcg.
750-1000 mcg subcutaneous daily for 2-3 weeks loading, 500 mcg weekly maintenance.
1000 mcg subcutaneous daily for 4 weeks loading, 1000 mcg weekly maintenance. Always monitor for new naevi or darkening of existing moles - annual dermatology check is recommended.
Commonly Stacked With
Generally not stacked with Melanotan-2 - overlapping receptor activity. Off-label users sometimes pair MT-1 with BPC-157 for healing during the loading phase. Monitor moles regardless of stacking.
Side Effects & Safety
Contraindications
Personal history of melanoma or dysplastic naevi syndrome. Pregnancy and breastfeeding. Active liver disease. Pediatric use is contraindicated outside specialist EPP protocols.
Additional Notes
Reconstitute with bacteriostatic water. A 10mg vial + 5mL BAC water = 2000 mcg/mL. 25 units = 500 mcg on insulin syringe.
Frequently Asked Questions
What is the recommended Melanotan-1 dosage?
The typical dose range for Melanotan-1 is 500-1000 mcg loading; 500 mcg maintenance. It is usually administered Daily during loading (2-4 weeks); weekly maintenance after. Always start with the lowest effective dose.
How often should I take Melanotan-1?
Daily during loading (2-4 weeks); weekly maintenance after
Does Melanotan-1 need to be cycled?
Yes, typical cycle length is 2-4 weeks loading, then weekly maintenance dosing.
What are Melanotan-1 side effects?
Trial-reported AEs: transient flushing, mild nausea (less than MT-2), headache, fatigue. Long-term: melanocyte changes (new naevi, darkening of existing moles). Theoretical: any MC1R-driven melanocyte activation in someone with melanoma history.
Where can I buy Melanotan-1?
Visit our vendor directory to find trusted sources for Melanotan-1.
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Dosing, reconstitution, stacks, half-lives, and vendor trust tiers. The reference we wish we had on day one.
