Also known as: Vasoactive Intestinal Peptide, Vasoactive Intestinal Polypeptide, PHM-27 precursor neuropeptide
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily.
Featured vendor
$10.00/mg$49.99 for 5mg
at Disguised Alpha · · median $8.95/mg
Overview
At A Glance
VIP acts on VPAC1 and VPAC2 receptors (G-protein coupled, Gs-linked), stimulating adenylyl cyclase and elevating cAMP in target cells. Central effects include modulation of the suprachiasmatic nucleus (SCN) — VIP is a key SCN neuropeptide regulating circadian rhythm synchronizati…
Overview
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily. VIP functions as a potent vasodilator and bronchodilator, as a neuromodulator in the brain (circadian rhythm, neuroprotection), as an immunomodulator with predominantly anti-inflammatory actions, and as a GI motility regulator. VIP has attracted research interest for CIRS (Chronic Inflammatory Response Syndrome), mast cell activation, small fiber neuropathy, and autonomic nervous system regulation. It is one of the few neuropeptides with simultaneous central, peripheral, and immune functions.
Chemical Information
IUPAC Name
Not yet available
CAS Number
Not yet available
Molecular Formula
Not yet available
Molecular Mass
3326.8
Amino Acid Sequence
Dosing & Protocols
Unlock the Dosing tab
Enter your email to keep reading. It is free, and it opens these tabs on every compound page in this browser.
- Route and how often
- Common vial sizes
You also get the free peptide cheat sheet by email. Unsubscribe anytime.
Have an account? Sign in
Research
Unlock the research summary
Enter your email to keep reading. It is free, and it opens these tabs on every compound page in this browser.
- A summary of the key research
- A link to the PubMed results
You also get the free peptide cheat sheet by email. Unsubscribe anytime.
Have an account? Sign in
Interactions
Interaction and contraindication data is being compiled for VIP. Check back soon.
General Safety Note
Always consult a qualified healthcare professional before combining research compounds. Interactions may exist that are not yet documented.
$49.99
up to $79.00
$7.9000
2
2
vial
| Vendor | Product | Form | Qty | Price | $/mg | Coupon | |
|---|---|---|---|---|---|---|---|
|
|
VIP 5 mg | vial | 1 vial● In Stock | $49.99BEST | $10.00 | — | |
 |
VIP 10mg | vial | 1 vial● In Stock | $79.00VALUE | $7.90 | — |
Tracking since Apr 22, 2026 · 2 data points
Price History
2 data pointsVendors Selling VIP
How we score these vendors
Every supplier above is graded 0 to 100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank.
Related Compounds
View AllAlpha-GPC
NootropicPhase 4Alpha-GPC (chemical name L-alpha-glycerylphosphorylcholine; pharmaceutical name choline alfoscerate) is a naturally occurring cholinergic compound that serves as a highly bioavailable precursor to both acetylcholine (the primary neurotransmitter of the cholinergic system, central to learning, memory, attention, and neuromuscular function) and phosphatidylcholine (the principal phospholipid building block of neuronal cell membranes).
Caffeine
NootropicPreclinicalCaffeine (1,3,7-trimethylxanthine) is a natural methylxanthine alkaloid found in the seeds, fruits, leaves, and bark of over 60 plant species — most notably Coffea (coffee), Camellia sinensis (tea), Theobroma cacao (cacao), Paullinia cupana (guaraná), Ilex paraguariensis (yerba mate), and Cola acuminata (kola nut).
CDP-Choline
NootropicPhase 4CDP-choline (cytidine 5'-diphosphocholine, pharmaceutical name citicoline) is a naturally occurring intracellular intermediate in the Kennedy pathway for phosphatidylcholine synthesis — the primary biochemical route by which all nucleated cells produce the dominant membrane phospholipid.
Inositol
NootropicPreclinicalInositol is a naturally-occurring cyclic sugar alcohol (cyclohexanehexol) that functions as a critical structural component of cell membranes and a second-messenger precursor in intracellular signaling.
L-Tryptophan
NootropicPreclinicalL-Tryptophan is one of the nine essential amino acids — meaning the human body cannot synthesize it and must obtain it from dietary protein — and is the direct metabolic precursor to serotonin, melatonin, and (via a separate route) the vitamin niacin (nicotinamide / NAD+).
Magnesium L-Threonate
NootropicPreclinicalMagnesium L-Threonate is a proprietary chelated form of magnesium in which the magnesium cation is bound to L-threonic acid — a metabolite of ascorbic acid (vitamin C) — forming the salt commonly marketed under the brand name Magtein.
View Full Dosage Guide →
Protocols, calculator & safety for VIP
Research Score
0 PubMed results
Quality Indicators
Data Completeness
63%COA Verification
0
Verified COAs
1
Vendors w/ COA
Latest test: 9/16/2026
Quick Facts
Half-Life
~1-2 minutes (plasma). VIP is very rapidly degraded by circulating peptidases, so systemic exposure is extremely short-lived regardless of administration route. Subcutaneous or intranasal absorption may modestly prolong the apparent duration of local/systemic effect, but this has not been well characterized in humans.
Molecular Weight
3326.8
Administration
Subcutaneous, Intranasal, Intravenous
Trial Phase
Clinical
Safety Profile
Common Side Effects
- • Facial flushing
- • Hypotension (vasodilatory effect)
- • Nausea
- • Tachycardia at higher doses
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is VIP used for in research?
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. It is a member of the glucagon superfamily. VIP functions as a potent vasodilator and bronchodilator, as a neuromodulator in the brain (circadian rhythm, neuroprotection), as an immunomodulator with predominantly anti-inflammatory actions, and as a GI motility regulator. VIP has attracted research interest for CIRS (Chronic Inflammatory Response Syndrome), mast cell activation, small fiber neuropathy, and autonomic nervous system regulation. It is one of the few neuropeptides with simultaneous central, peripheral, and immune functions.
What forms does VIP come in?
VIP is available in vial form.
How do I compare VIP vendors?
Compare prices, payment methods, shipping, and COA scores across 2 vendors.
How many vendors sell VIP, and what does it cost per mg?
2 of the vendors BodyHackGuide tracks list VIP (2 listings). Among BodyHackGuide's VIP listings recorded as in stock with a milligram count, the lowest price per milligram is $7.90/mg at Ion Peptide and the median is $8.95/mg. The VIP prices on BodyHackGuide are vendors' listed prices as BodyHackGuide last recorded them, not transactions; the most recent recorded change to a VIP listing is dated 5 September 2026.
Which vendors have third-party COAs for VIP on file at BodyHackGuide?
BodyHackGuide holds 24 third-party certificate records for VIP, from BHG Labs. An editor has read 2 of BodyHackGuide's 24 certificate records for VIP and recorded the laboratory, the compound and the test date as printed on each. The laboratories named on BodyHackGuide's VIP certificate records are ILS Laboratories and Freedom Diagnostics Testing, and the newest test date on them is 1 October 2026. Each vendor page on BodyHackGuide shows how many certificate records BodyHackGuide holds for that vendor and links to each record that has its own page.
Research Tools
Related Compounds
View AllAlpha-GPC
NootropicPhase 4Alpha-GPC (chemical name L-alpha-glycerylphosphorylcholine; pharmaceutical name choline alfoscerate) is a naturally occurring cholinergic compound that serves as a highly bioavailable precursor to both acetylcholine (the primary neurotransmitter of the cholinergic system, central to learning, memory, attention, and neuromuscular function) and phosphatidylcholine (the principal phospholipid building block of neuronal cell membranes).
Caffeine
NootropicPreclinicalCaffeine (1,3,7-trimethylxanthine) is a natural methylxanthine alkaloid found in the seeds, fruits, leaves, and bark of over 60 plant species — most notably Coffea (coffee), Camellia sinensis (tea), Theobroma cacao (cacao), Paullinia cupana (guaraná), Ilex paraguariensis (yerba mate), and Cola acuminata (kola nut).
CDP-Choline
NootropicPhase 4CDP-choline (cytidine 5'-diphosphocholine, pharmaceutical name citicoline) is a naturally occurring intracellular intermediate in the Kennedy pathway for phosphatidylcholine synthesis — the primary biochemical route by which all nucleated cells produce the dominant membrane phospholipid.
Inositol
NootropicPreclinicalInositol is a naturally-occurring cyclic sugar alcohol (cyclohexanehexol) that functions as a critical structural component of cell membranes and a second-messenger precursor in intracellular signaling.
L-Tryptophan
NootropicPreclinicalL-Tryptophan is one of the nine essential amino acids — meaning the human body cannot synthesize it and must obtain it from dietary protein — and is the direct metabolic precursor to serotonin, melatonin, and (via a separate route) the vitamin niacin (nicotinamide / NAD+).
Magnesium L-Threonate
NootropicPreclinicalMagnesium L-Threonate is a proprietary chelated form of magnesium in which the magnesium cation is bound to L-threonic acid — a metabolite of ascorbic acid (vitamin C) — forming the salt commonly marketed under the brand name Magtein.
Free 2026 Peptide Cheat Sheet (PDF)
38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers.