Snap-8
Skin & HairPreclinicalAlso known as: Acetyl Glutamyl Heptapeptide-1, SNAP-8, Leuphasyl, anti-wrinkle peptide
Snap-8 (INCI: Acetyl Glutamyl Heptapeptide-1) is a synthetic octapeptide designed as an analog of the N-terminal fragment of synaptosomal-associated protein of 25 kDa (SNAP-25), which is the molecular target of botulinum toxin A (Botox). Where Botox cleaves SNAP-25 systemically and irreversibly via enzymatic activity, Snap-8 competes with SNAP-25 for a place in the SNARE complex that enables acetylcholine release at the neuromuscular junction.
Overview
At A Glance
SNARE (Soluble NSF Attachment Protein Receptor) complex formation is required for synaptic vesicle fusion and acetylcholine release at the neuromuscular junction. SNAP-25, Syntaxin-1, and VAMP/Synaptobrevin form the SNARE complex that drives vesicle fusion. Snap-8's amino acid se…
Overview
Snap-8 (INCI: Acetyl Glutamyl Heptapeptide-1) is a synthetic octapeptide designed as an analog of the N-terminal fragment of synaptosomal-associated protein of 25 kDa (SNAP-25), which is the molecular target of botulinum toxin A (Botox). Where Botox cleaves SNAP-25 systemically and irreversibly via enzymatic activity, Snap-8 competes with SNAP-25 for a place in the SNARE complex that enables acetylcholine release at the neuromuscular junction. This competitive inhibition reduces muscle contraction at the application site without systemic toxin effects. Snap-8 is used in cosmetic research as a topical anti-wrinkle agent, particularly for expression lines (forehead, periorbital). Purity-verified Snap-8 raw powder is also used in cosmetic compounding research.
Chemical Information
IUPAC Name
Not yet available
CAS Number
Not yet available
Molecular Formula
Not yet available
Molecular Mass
Not yet available
Chemical data is being compiled for this compound.
Dosing & Protocols
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Research
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Interactions
Interaction and contraindication data is being compiled for Snap-8. Check back soon.
General Safety Note
Always consult a qualified healthcare professional before combining research compounds. Interactions may exist that are not yet documented.
$39.00
up to $199.99
$0.1490
2
3
vial, powder, topical
| Vendor | Product | Form | Qty | Price | $/mg | Coupon | |
|---|---|---|---|---|---|---|---|
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Double Diamond Balm | topical | 30ml● In Stock | $199.99BEST | — | ||
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Snap-8 10mg (injectable) | vial | 1 vial● Out of Stock | $39.00 | $3.900 | — | Sign in for stock alert |
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Snap-8 Raw 1g | powder | 1g● In Stock | $149.00VALUE | $0.149 | — |
Tracking since Apr 22, 2026 · 3 data points
Price History
2 data pointsVendors Selling Snap-8
How we score these vendors
Every supplier above is graded 0–100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank.
Related Compounds
View AllAcetyl Hexapeptide-8
Skin & HairPreclinicalAcetyl Hexapeptide-8 (INCI: Acetyl Hexapeptide-3 in older nomenclature, commercially known as Argireline) is a synthetic hexapeptide designed as a competitive inhibitor of the SNARE complex at the neuromuscular junction.
AHK-Cu
Skin & HairPreclinicalAHK-Cu (Ala-His-Lys-Copper) is a copper chelating tripeptide related to but distinct from GHK-Cu (Gly-His-Lys-Copper).
Melanotan 2
Skin & HairPhase IIA synthetic melanocortin receptor agonist studied for skin tanning, sexual function, and appetite suppression..
Minoxidil
Skin & HairPreclinicalFDA-approved topical vasodilator used for hair regrowth.
PDRN
Skin & HairPhase 4PDRN (Polydeoxyribonucleotide) is a biotechnological compound derived from salmon sperm DNA (Oncorhynchus mykiss) through extraction, purification, and fractionation.
View Full Dosage Guide →
Protocols, calculator & safety for Snap-8
Research Score
0 PubMed studies
Quality Indicators
Data Completeness
63%COA Verification
4
Verified COAs
1
Vendors w/ COA
Latest test: 3/1/2026
Quick Facts
Half-Life
Not characterized (topical peptide)
Administration
Topical
Trial Phase
Preclinical
Safety Profile
Common Side Effects
- • Minimal — well tolerated at cosmetic concentrations
- • Mild transient erythema at high concentrations
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is Snap-8 used for in research?
Snap-8 (INCI: Acetyl Glutamyl Heptapeptide-1) is a synthetic octapeptide designed as an analog of the N-terminal fragment of synaptosomal-associated protein of 25 kDa (SNAP-25), which is the molecular target of botulinum toxin A (Botox). Where Botox cleaves SNAP-25 systemically and irreversibly via enzymatic activity, Snap-8 competes with SNAP-25 for a place in the SNARE complex that enables acetylcholine release at the neuromuscular junction. This competitive inhibition reduces muscle contraction at the application site without systemic toxin effects. Snap-8 is used in cosmetic research as a topical anti-wrinkle agent, particularly for expression lines (forehead, periorbital). Purity-verified Snap-8 raw powder is also used in cosmetic compounding research.
What forms does Snap-8 come in?
Snap-8 is available in vial, powder, topical forms.
How much does Snap-8 cost?
Prices start at $39.00 across 2 verified vendors.
How do I compare Snap-8 vendors?
Compare prices, payment methods, shipping, and COA scores across 2 vendors.
Research Tools
Related Compounds
View AllAcetyl Hexapeptide-8
Skin & HairPreclinicalAcetyl Hexapeptide-8 (INCI: Acetyl Hexapeptide-3 in older nomenclature, commercially known as Argireline) is a synthetic hexapeptide designed as a competitive inhibitor of the SNARE complex at the neuromuscular junction.
AHK-Cu
Skin & HairPreclinicalAHK-Cu (Ala-His-Lys-Copper) is a copper chelating tripeptide related to but distinct from GHK-Cu (Gly-His-Lys-Copper).
Melanotan 2
Skin & HairPhase IIA synthetic melanocortin receptor agonist studied for skin tanning, sexual function, and appetite suppression..
Minoxidil
Skin & HairPreclinicalFDA-approved topical vasodilator used for hair regrowth.
PDRN
Skin & HairPhase 4PDRN (Polydeoxyribonucleotide) is a biotechnological compound derived from salmon sperm DNA (Oncorhynchus mykiss) through extraction, purification, and fractionation.
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