Phenylpiracetam vs Dihexa
Side-by-side comparison of Phenylpiracetam and Dihexa: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Phenylpiracetam
Dihexa
Phenylpiracetam
Phenylpiracetam is a Russian-developed phenyl derivative of piracetam with a dramatically higher potency and stimulant profile. Approved in Russia as Phenotropil/Carphedon for cognitive impairment and stroke recovery.…
Lowest listed price: $84.99 across 1 listing
Full Phenylpiracetam profileDihexa
Dihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University. It is considered one of the most potent cognitive enhancers ever tested in animal models…
Lowest listed price: $79.99 across 3 listings
Full Dihexa profileSide-by-side comparison
| Attribute | Phenylpiracetam | Dihexa |
|---|---|---|
| Category | Nootropics | Nootropics |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | Phenylpiracetam's phenyl group addition dramatically increases lipophilicity and blood-brain barrier penetration compared to piracetam. It upregulates dopamine, norepinephrine, and serotonin receptor density — rather than triggering release — explaining the… | Dihexa is a small-molecule analog derived from angiotensin IV (AngIV). It retains the Tyr-Ile core of Nle1-AngIV, with an N-terminal hexanoic acid cap and a C-terminal 6-aminohexanoic amide that give it metabolic stability and blood-brain-barrier penetration.… |
| Half-Life | — | Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence. |
| Typical Dose Range | — | 5 to 40 mg oral per day (anecdotal range; no established human dose) |
| Dosing Frequency | — | Once daily (oral), typically in the morning |
| Administration | — | Oral, Intranasal, Subcutaneous |
| Side Effects | Insomnia (if taken late), headache, slight anxiety at initiation, overstimulation at high doses. Generally well-tolerated. | No controlled human safety data. Anecdotal user reports include headache, fatigue, irritability or anxiety, insomnia, and vivid dreams, usually at higher doses. The most serious concern is theoretical rather than reported: because dihexa acts on the HGF/c-Met… |
| Molecular Weight | 218.25 g/mol | 504.7 g/mol |
| Common Vial Sizes | — | 50mg, 100mg |
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2 data pointsPhenylpiracetam: potential benefits
- Cognitive stimulation
- Physical performance
- Memory enhancement
- Cold tolerance
- Motivation
- Anti-convulsant
Dihexa: potential benefits
- Synaptogenesis: formation of new dendritic spines and functional synapses (preclinical)
- Memory and spatial-learning support in rodent models
- Potential research application in Alzheimer's and other neurodegenerative disease models
- HGF/c-Met and PI3K/Akt-linked neuroplasticity (mechanism proposed; key paper retracted)
Frequently asked
What's the difference between Phenylpiracetam and Dihexa?
Phenylpiracetam is a nootropics that phenylpiracetam's phenyl group addition dramatically increases lipophilicity and blood-brain barrier penetration compared to piracetam. it upregulates dopamine, norepinephrine, and…. Dihexa is a nootropics that dihexa is a small-molecule analog derived from angiotensin iv (angiv). it retains the tyr-ile core of nle1-angiv, with an n-terminal hexanoic acid cap and a c-terminal…. The two differ in mechanism, half-life (not reported vs Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence.), and typical dose range.
Which has the longer half-life, Phenylpiracetam or Dihexa?
Phenylpiracetam has a half-life of not reported. Dihexa has a half-life of Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, Phenylpiracetam or Dihexa?
Lowest listed price on BodyHackGuide: Phenylpiracetam from $84.99, Dihexa from $79.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack Phenylpiracetam and Dihexa?
Stacking depends on mechanism overlap, safety profile, and goals. Phenylpiracetam and Dihexa should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Before you buy Phenylpiracetam or Dihexa
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.