N-Acetyl-Selank vs N-Acetyl-Semax
Independent, side-by-side comparison of N-Acetyl-Selank and N-Acetyl-Semax: mechanism, half-life, dose range, safety profile, and live vendor pricing. Updated continuously as new research and listings land.
Live price snapshot
N-Acetyl-Selank
N-Acetyl-Semax
N-Acetyl-Selank
N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a tuftsin-derived heptapeptide used intranasally for its reported anxiolytic and nootropic effects. The acetyl group is claimed to improve stability and…
Full N-Acetyl-Selank profileN-Acetyl-Semax
This is a duplicate/alias entry. The full, maintained guide for this compound lives at NA-Semax (/compound/na-semax). See that page for mechanism, dosing, evidence, and safety.
Full N-Acetyl-Semax profileSide-by-side comparison
| Attribute | N-Acetyl-Selank | N-Acetyl-Semax |
|---|---|---|
| Category | Cognitive | Cognitive |
| Research Stage | Preclinical (the N-acetyl analog has no dedicated studies); parent Selank has limited clinical use in Russia | Duplicate entry - see NA-Semax |
| Mechanism of Action | N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg) with a C-terminal Pro-Gly-Pro tail added to slow enzymatic breakdown.… | See the full guide This page is a duplicate of NA-Semax, which is the canonical, maintained entry. To avoid conflicting or outdated information, all detail - mechanism of action, protocols, dosing, side effects, and verified citations - is kept on that single… |
| Half-Life | Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature. | — |
| Typical Dose Range | 100-900 | — |
| Dosing Frequency | Once or twice daily (intranasal); some advanced users split into 2-3 doses | — |
| Administration | — | — |
| Side Effects | In short Russian clinical trials, parent Selank was generally well tolerated with no serious adverse effects reported [PMID:18454096]. Reported or plausible effects (largely extrapolated to the analog): mild nasal irritation or congestion from the spray,… | — |
| Molecular Weight | ~793.9 g/mol (theoretical: Selank ~751.9 g/mol + N-terminal acetyl, ~+42). Approximate molecular formula C35H59N11O10. | — |
| Common Vial Sizes | — | — |
Price History
2 data points- Unknown
- VANDL Labs
Price History
2 data points- Unknown
- VANDL Labs
N-Acetyl-Selank — potential benefits
- Anxiolytic (calming) effects - the most-studied action of parent Selank, including a Russian clinical trial in generalized anxiety disorder [PMID:18454096]
- Nootropic / cognitive support - reported attention and memory benefits in rodent models, linked to BDNF changes [PMID:31625062]
- Stress resilience reported without the sedation, tolerance, or dependence typically seen with benzodiazepines (preclinical framing) [PMID:30255741]
- Possible support during withdrawal states (alcohol, opioid) in animal models [PMID:24913576][PMID:36322304]
- Claimed longer duration vs. plain Selank from N-terminal acetylation - a community/vendor claim not verified in published data
N-Acetyl-Semax — potential benefits
- See the full guide at NA-Semax (/compound/na-semax) for benefits and evidence.
Frequently asked
What's the difference between N-Acetyl-Selank and N-Acetyl-Semax?
N-Acetyl-Selank is a cognitive that n-acetyl-selank is the n-terminally acetylated analog of selank, a synthetic heptapeptide (thr-lys-pro-arg-pro-gly-pro) derived from the endogenous immunopeptide tuftsin…. N-Acetyl-Semax is a cognitive that see the full guide this page is a duplicate of na-semax, which is the canonical, maintained entry. to avoid conflicting or outdated information, all detail - mechanism of action,…. The two differ in mechanism, half-life (Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature. vs not reported), and typical dose range.
Which has the longer half-life, N-Acetyl-Selank or N-Acetyl-Semax?
N-Acetyl-Selank has a half-life of Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature.. N-Acetyl-Semax has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack N-Acetyl-Selank and N-Acetyl-Semax?
Stacking depends on mechanism overlap, safety profile, and goals. N-Acetyl-Selank and N-Acetyl-Semax should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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