DSIP (Delta Sleep-Inducing Peptide) vs Pinealon
Side-by-side comparison of DSIP (Delta Sleep-Inducing Peptide) and Pinealon: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
DSIP (Delta Sleep-Inducing Peptide)
Pinealon
DSIP (Delta Sleep-Inducing Peptide)
Delta sleep-inducing peptide (DSIP) is a nonapeptide — a 9-amino-acid neuropeptide with sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE, 848 Da molecular weight) — first isolated in 1977 from the cerebral venous…
Lowest listed price: $34.99 across 11 listings
Full DSIP (Delta Sleep-Inducing Peptide) profilePinealon
Pinealon is a synthetic tripeptide — glutamyl-aspartyl-arginine (Glu-Asp-Arg, or EDR) — developed by the St Petersburg Institute of Bioregulation and Gerontology (IBG) under the leadership of Professor Vladimir…
Lowest listed price: $45.00 across 3 listings
Full Pinealon profileSide-by-side comparison
| Attribute | DSIP (Delta Sleep-Inducing Peptide) | Pinealon |
|---|---|---|
| Category | Cognition, Mood & Neuroprotection | Nootropics |
| Research Stage | Research Use Only | Preclinical |
| Mechanism of Action | Primary Mechanism: Uncharacterized Direct Receptor Binding After more than four decades of research, DSIP's primary molecular target remains unknown. No specific receptor has been cloned, characterized, or reproducibly identified as the primary binding site… | The proposed mechanism of Pinealon is rooted in the Khavinson school's broader theory of short-peptide tissue-specific bioregulation. The full theory is worth understanding because it underlies all twelve Russian bioregulator compounds in this catalog. The… |
| Half-Life | ~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels) | Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing. |
| Typical Dose Range | 100–300 mcg per injection | Subcutaneous (primary route): 2-10 mg/day, typically 3-5 mg, in pulsed 10-20 day cycles, 2-4 cycles/year. Intranasal: 150-800 mcg per nostril daily. Research use only; oral dosing is not recommended because the peptide is largely degraded by GI proteases. |
| Dosing Frequency | Once daily, 30–60 minutes before bedtime | Once daily during a cycle (morning preferred); some advanced users split into AM + midday doses. Not dosed continuously year-round - cycles are pulsed. |
| Administration | Subcutaneous, Intramuscular, Intranasal | — |
| Side Effects | Overall Safety Profile DSIP has one of the cleanest safety profiles of any peptide in the research chemical space. In 40+ years of research and clinical use, no serious adverse events have been reported in controlled trials or large case series. The compound… | The side-effect profile of Pinealon, based on the available Russian clinical literature and user-reported experience, is described as mild and uncommon. Whether this reflects genuinely low toxicity or inadequate reporting in the available studies is a… |
| Molecular Weight | 848.8 Da | 418.40 g/mol (C15H26N6O8) |
| Common Vial Sizes | 2mg, 5mg | — |
Price History
8 data points- BM
- Half Nattys
- LB
- Ion Peptide
- OF
- Disguised Alpha
- BHG Labs
Price History
2 data points- Ion Peptide
- Disguised Alpha
DSIP (Delta Sleep-Inducing Peptide): potential benefits
- Sleep quality support
- Stress reduction
- Cortisol/HPA modulation
- Alcohol & opioid withdrawal support
- Circadian regulation
Pinealon: potential benefits
- Neuroprotection against oxidative and hypoxic stress (preclinical models)
- Antioxidant support - reduced oxidative DNA damage in aged neurons (in vitro)
- Cognitive and memory support in aging populations (small Russian clinical reports)
- Reduced neuronal apoptosis and support of dendritic-tree integrity in cell models
- Investigated for neuroprotection in Alzheimer's-model systems (preclinical)
Frequently asked
What's the difference between DSIP (Delta Sleep-Inducing Peptide) and Pinealon?
DSIP (Delta Sleep-Inducing Peptide) is a cognition, mood & neuroprotection that primary mechanism: uncharacterized direct receptor binding after more than four decades of research, dsip's primary molecular target remains unknown. no specific receptor has been…. Pinealon is a nootropics that the proposed mechanism of pinealon is rooted in the khavinson school's broader theory of short-peptide tissue-specific bioregulation. the full theory is worth understanding because…. The two differ in mechanism, half-life (~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels) vs Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing.), and typical dose range.
Which has the longer half-life, DSIP (Delta Sleep-Inducing Peptide) or Pinealon?
DSIP (Delta Sleep-Inducing Peptide) has a half-life of ~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels). Pinealon has a half-life of Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, DSIP (Delta Sleep-Inducing Peptide) or Pinealon?
Lowest listed price on BodyHackGuide: DSIP (Delta Sleep-Inducing Peptide) from $34.99, Pinealon from $45.00. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack DSIP (Delta Sleep-Inducing Peptide) and Pinealon?
Stacking depends on mechanism overlap, safety profile, and goals. DSIP (Delta Sleep-Inducing Peptide) and Pinealon should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.