Sabroxy (Oroxylin A) Dosage Guide: Protocols, Calculator & Safety
Everything you need to know about Sabroxy (Oroxylin A) dosing — protocols, safety, and where to buy.
Dose Range
500000-1000000
Frequency
Once to twice daily (500 mg per dose)
Cycle Length
Studied continuously for 12 weeks; users often cycle (e.g., 5 on / 2 off, or 8-12 week blocks with breaks) to limit tolerance - cycling is anecdotal, not trial-derived.
Dosage Calculator
Calculate exact dosing for Sabroxy (Oroxylin A).
Dosing Protocols
Research-use framing only; not medical advice. Most human data used a standardized Oroxylum indicum extract (10% oroxylin A). A conservative starting point is half the studied daily dose: 500 mg once daily, taken in the morning with food. Because oroxylin A has stimulant-like, dopaminergic and wake-promoting properties in animal models [PMID:23371806], morning dosing helps avoid sleep disruption. Assess tolerability - headache or mild stomach upset are the most commonly reported effects - over 1-2 weeks before considering the full studied dose.
The dose used in the only published human trial was 500 mg twice daily (1,000 mg/day) of a standardized extract for 12 weeks in adults with self-reported mild cognitive complaints [PMID:34531736]. Take one 500 mg dose in the morning and one in the early afternoon, with food; avoid late-day dosing given the wake-promoting profile. Give it several weeks - the trial measured cognitive outcomes at 12 weeks, not acutely. RUO; not medical advice.
Experienced users sometimes run the full 500 mg twice daily dose and cycle it (for example 5 days on / 2 off, or 8-12 week blocks with a break) to limit tolerance to the dopaminergic effect - this cycling is anecdotal, not trial-derived. Sabroxy is occasionally stacked with cholinergics (citicoline, alpha-GPC) or L-theanine to soften stimulation; none of these combinations has been formally studied. Do not combine with prescription stimulants, dopaminergic drugs, or MAO inhibitors without medical supervision. RUO; not medical advice.
Side Effects & Safety
Contraindications
Not for use in pregnancy or breastfeeding (no safety data). Caution with, or avoid, prescription stimulants, dopaminergic agents, or MAO inhibitors given the dopaminergic mechanism [PMID:23371806]. The extract's flavones (baicalein, chrysin) may affect drug-metabolizing enzymes, so caution is warranted with medications that have a narrow therapeutic window. Anyone with a psychiatric, cardiovascular, or seizure history, or on prescription medication, should consult a clinician first. RUO; not medical advice.
Additional Notes
Doses refer to the extract (mg), not isolated oroxylin A. The dose_range_mcg field expresses the daily range in micrograms (500,000-1,000,000 mcg = 500-1,000 mg). At 10% standardization, a 500 mg dose delivers roughly 50 mg oroxylin A. RUO.
Frequently Asked Questions
What is the recommended Sabroxy (Oroxylin A) dosage?
The typical dose range for Sabroxy (Oroxylin A) is 500000-1000000. It is usually administered Once to twice daily (500 mg per dose). Always start with the lowest effective dose.
How often should I take Sabroxy (Oroxylin A)?
Once to twice daily (500 mg per dose)
Does Sabroxy (Oroxylin A) need to be cycled?
Yes, typical cycle length is Studied continuously for 12 weeks; users often cycle (e.g., 5 on / 2 off, or 8-12 week blocks with breaks) to limit tolerance - cycling is anecdotal, not trial-derived..
What are Sabroxy (Oroxylin A) side effects?
In the 12-week human trial the extract was well tolerated; the only notable adverse effects versus placebo were a slightly higher rate of mild digestive complaints and headaches [PMID:34531736]. Because of its stimulant-like, dopaminergic and wake-promoting activity in animal models [PMID:23371806], some users report jitteriness, restlessness, or disrupted sleep if it is taken late in the day. Long-term human safety data do not exist. RUO.
Where can I buy Sabroxy (Oroxylin A)?
Visit our vendor directory to find trusted sources for Sabroxy (Oroxylin A).
Free 2026 Peptide Cheat Sheet — 50 pages, PDF
Reconstitution math, concentration charts, half-lives, and vendor trust tiers. The reference we wish we had on day one.