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    NootropicsPreclinical

    Fladrafinil (CRL-40,941) Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about Fladrafinil (CRL-40,941) dosing: protocols, safety, and where to buy.

    Half-Life

    Not established in humans; after a single 20 mg oral dose in six volunteers, urinary fladrafinil peaked at 2 to 4 h and stayed detectable for up to 12 h, while the metabolite flmodafinil was detectable for about 8 days and the acid and sulfone metabolites for about two weeks (PMID: 42210629)

    Administration Routes

    Oral

    Dosage Calculator

    Calculate exact dosing for Fladrafinil (CRL-40,941).

    Dosing data for Fladrafinil (CRL-40,941) is being researched. Check the compound page for the latest information.

    Side Effects & Safety

    No safety trial has been published. The only human administration study was a six-person single-dose pharmacokinetic study run for doping-control purposes, and it did not report adverse events (PMID: 42210629). Products bought from supplement sellers for that study were mislabelled for content, one containing nearly twice the stated concentration (PMID: 42210629), so what reaches a buyer may not match the label. Adverse effects reported for the parent compound modafinil cannot be assumed to transfer unchanged to a difluorinated analog.

    Contraindications

    Mechanism-based: fladrafinil is converted to a compound of the modafinil class, and modafinil occupies dopamine transporters and raises brain dopamine in humans, an effect the investigators linked to abuse potential in vulnerable people (PMID: 19293415). Athletes subject to anti-doping testing should treat it as prohibited in competition (PMID: 42210629). No pregnancy, hepatic or cardiac safety data exist for fladrafinil in any species.

    Check interactions with the Interaction Checker →

    Frequently Asked Questions

    What is the recommended Fladrafinil (CRL-40,941) dosage?

    Dosage for Fladrafinil (CRL-40,941) varies by protocol. Consult a qualified healthcare provider.

    How often should I take Fladrafinil (CRL-40,941)?

    Administration frequency depends on the specific protocol. Consult current research literature.

    Does Fladrafinil (CRL-40,941) need to be cycled?

    Cycling requirements depend on the protocol. Follow established research guidelines.

    What are Fladrafinil (CRL-40,941) side effects?

    No safety trial has been published. The only human administration study was a six-person single-dose pharmacokinetic study run for doping-control purposes, and it did not report adverse events (PMID: 42210629). Products bought from supplement sellers for that study were mislabelled for content, one containing nearly twice the stated concentration (PMID: 42210629), so what reaches a buyer may not match the label. Adverse effects reported for the parent compound modafinil cannot be assumed to transfer unchanged to a difluorinated analog.

    Where can I buy Fladrafinil (CRL-40,941)?

    Compare 1 listings from 1 vendor on our price comparison page, starting from $74.99.

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