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    Cardarine (GW501516) Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about Cardarine (GW501516) dosing: protocols, safety, and where to buy.

    Half-Life

    Not reported in the published human trials; the phase 1 and phase 2 studies described lipid outcomes over two to twelve weeks of oral dosing without publishing a terminal half-life (PMID: 17110604; PMID: 22814748)

    Administration Routes

    Oral

    Dosage Calculator

    Calculate exact dosing for Cardarine (GW501516).

    Dosing data for Cardarine (GW501516) is being researched. Check the compound page for the latest information.

    Side Effects & Safety

    The published human trials, lasting two to twelve weeks, did not report a distinctive adverse effect pattern, and one study reported a 30 percent reduction in urinary isoprostanes, a marker of oxidative stress (PMID: 18024853). Long-term human safety is unknown because no trial ran longer than twelve weeks (PMID: 22814748). The significant animal finding is tumor promotion: GW501516 increased the number and size of intestinal polyps in Apc(min) mice (PMID: 14758356) and accelerated colorectal tumorigenesis in a later mouse model (PMID: 30679176). Reviewers concluded that PPAR-delta agonists in development might increase tumor risk in humans (PMID: 15539957).

    Contraindications

    Mechanism-based and animal-data-based: the demonstrated promotion of intestinal tumor growth in mice argues against use by anyone with a personal or family history of colorectal polyps, colorectal cancer or Lynch-type syndromes (PMID: 14758356; PMID: 30679176). No human pregnancy, lactation, pediatric, hepatic or renal impairment data exist. Prohibited at all times in tested sport under WADA section S4.4 (PMID: 19946680).

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    Frequently Asked Questions

    What is the recommended Cardarine (GW501516) dosage?

    Dosage for Cardarine (GW501516) varies by protocol. Consult a qualified healthcare provider.

    How often should I take Cardarine (GW501516)?

    Administration frequency depends on the specific protocol. Consult current research literature.

    Does Cardarine (GW501516) need to be cycled?

    Cycling requirements depend on the protocol. Follow established research guidelines.

    What are Cardarine (GW501516) side effects?

    The published human trials, lasting two to twelve weeks, did not report a distinctive adverse effect pattern, and one study reported a 30 percent reduction in urinary isoprostanes, a marker of oxidative stress (PMID: 18024853). Long-term human safety is unknown because no trial ran longer than twelve weeks (PMID: 22814748). The significant animal finding is tumor promotion: GW501516 increased the number and size of intestinal polyps in Apc(min) mice (PMID: 14758356) and accelerated colorectal tumorigenesis in a later mouse model (PMID: 30679176). Reviewers concluded that PPAR-delta agonists in development might increase tumor risk in humans (PMID: 15539957).

    Where can I buy Cardarine (GW501516)?

    Compare 1 listings from 1 vendor on our price comparison page, starting from $84.99.

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