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    MetabolicFDA Approved

    Amlexanox Dosage Guide: Protocols, Calculator & Safety

    Everything you need to know about Amlexanox dosing: protocols, safety, and where to buy.

    Half-Life

    Not established in published human pharmacokinetic studies for the oral capsule form; a validated plasma assay has been used for preclinical pharmacokinetics in rats (PMID: 34842293)

    Administration Routes

    OralTopical oral paste

    Dosage Calculator

    Calculate exact dosing for Amlexanox.

    Dosing data for Amlexanox is being researched. Check the compound page for the latest information.

    Side Effects & Safety

    Human safety data come mainly from topical oral paste use since 1996 and from one twelve-week randomized trial of oral amlexanox in 42 obese patients with type 2 diabetes and fatty liver disease, which reported the drug as tolerable enough to complete the study (PMID: 28683283). An earlier version of that protocol was terminated after seven participants (NCT01842282). Long-term safety of systemic oral amlexanox has not been established, and no dose-ranging safety study in people without diabetes has been published. Preclinical pharmacokinetics have been characterized in rats (PMID: 34842293).

    Contraindications

    Label-based for the approved topical paste, which carries its own prescribing information. For oral systemic use, no contraindications have been established because only one completed trial exists (PMID: 28683283). Mechanism-based caution applies: TBK1 and IKK-epsilon are central to antiviral interferon signaling, and amlexanox inhibits type I interferon production and B cell differentiation in laboratory studies (PMID: 40341181), so immune consequences of sustained inhibition are unquantified in humans. No pregnancy, lactation or pediatric data exist for systemic use.

    Check interactions with the Interaction Checker →

    Frequently Asked Questions

    What is the recommended Amlexanox dosage?

    Dosage for Amlexanox varies by protocol. Consult a qualified healthcare provider.

    How often should I take Amlexanox?

    Administration frequency depends on the specific protocol. Consult current research literature.

    Does Amlexanox need to be cycled?

    Cycling requirements depend on the protocol. Follow established research guidelines.

    What are Amlexanox side effects?

    Human safety data come mainly from topical oral paste use since 1996 and from one twelve-week randomized trial of oral amlexanox in 42 obese patients with type 2 diabetes and fatty liver disease, which reported the drug as tolerable enough to complete the study (PMID: 28683283). An earlier version of that protocol was terminated after seven participants (NCT01842282). Long-term safety of systemic oral amlexanox has not been established, and no dose-ranging safety study in people without diabetes has been published. Preclinical pharmacokinetics have been characterized in rats (PMID: 34842293).

    Where can I buy Amlexanox?

    Compare 1 listings from 1 vendor on our price comparison page, starting from $79.99.

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