AICAR (acadesine) Dosage Guide: Protocols, Calculator & Safety
Everything you need to know about AICAR (acadesine) dosing: protocols, safety, and where to buy.
Half-Life
Intact acadesine was measurable in plasma for only about 2 hours after a short intravenous infusion in four healthy men, with total plasma clearance of 2.2 L/h/kg and negligible protein binding; radiolabeled drug-derived material had an apparent terminal half-life of about one week, reflecting metabolites rather than parent compound (PMID: 8227467)
Administration Routes
Quick Reconstitution Calculator
Calculate syringe units instantly
Syringe Draw
10.0 units
2500 mcg/ml · 0.100 ml draw
For laboratory research use only. This tool performs reconstitution math (concentration and syringe-unit conversion) and is not dosing guidance for humans or animals.
Dosing data for AICAR (acadesine) is being researched. Check the compound page for the latest information.
Side Effects & Safety
Contraindications
Mechanism-based: because acadesine is metabolized mainly to uric acid in humans, it is a poor fit for anyone with gout, hyperuricemia or impaired kidney function (PMID: 8227467; PMID: 23228986). Infusion-related hypotension was reported in the leukemia study, so people on blood pressure lowering therapy face an additive effect. Prohibited in tested sport under WADA section S4.4. No pregnancy, lactation or pediatric safety data exist.
Frequently Asked Questions
What is the recommended AICAR (acadesine) dosage?
Dosage for AICAR (acadesine) varies by protocol. Consult a qualified healthcare provider.
How often should I take AICAR (acadesine)?
Administration frequency depends on the specific protocol. Consult current research literature.
Does AICAR (acadesine) need to be cycled?
Cycling requirements depend on the protocol. Follow established research guidelines.
What are AICAR (acadesine) side effects?
In the leukemia phase I/II study, intravenous acadesine commonly caused hyperuricemia, along with transient anemia and thrombocytopenia, renal impairment and infusion-related hypotension; the hyperuricemia was managed with allopurinol prophylaxis (PMID: 23228986). Uric acid is the major human metabolite, which explains the urate load (PMID: 8227467). The 3080-patient cardiac surgery trial did not report an excess of harm but also showed no benefit (PMID: 22782417). No safety data exist for oral use or for the powder sold to consumers.
Where can I buy AICAR (acadesine)?
Compare 1 listings from 1 vendor on our price comparison page, starting from $49.99.
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