Nefiracetam
NootropicsClinical (marketed in Japan; research-use in US)Also known as: DM-9384, DM9384, Translon
Nefiracetam (DM-9384) is a fat-soluble pyrrolidone (racetam-class) nootropic research compound developed in Japan and studied for cognitive impairment in cerebrovascular and Alzheimer-type dementia. Unlike water-soluble racetams such as piracetam, its lipophilicity is thought to support good CNS penetration.
Overview
At A Glance
Nefiracetam acts across several systems rather than a single target. It potentiates nicotinic and muscarinic acetylcholine receptor signaling, prolongs the opening of N- and L-type voltage-gated calcium channels (sustaining calcium-dependent neurotransmitter release), and enhance…
Overview
Nefiracetam (DM-9384) is a fat-soluble pyrrolidone (racetam-class) nootropic research compound developed in Japan and studied for cognitive impairment in cerebrovascular and Alzheimer-type dementia. Unlike water-soluble racetams such as piracetam, its lipophilicity is thought to support good CNS penetration. It is a prescription product in Japan and is sold in the US as a research compound.
Chemical Information
IUPAC Name
Not yet available
CAS Number
77191-36-7
Molecular Formula
C14H18N2O2
Molecular Mass
246.30 g/mol
Dosing & Protocols
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Research
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Interactions
Contraindications
Pregnancy or breastfeeding; known hypersensitivity. Use caution combining with other cholinergic or GABAergic compounds.
Research Disclaimer
This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.
$44.99
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1
1
capsule
Tracking since Jul 1, 2026 · 1 data point
Vendors Selling Nefiracetam
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Related Compounds
View All9-Me-BC (9-Methyl-β-carboline)
NootropicsPreclinical9-Methyl--carboline (9-Me-BC) is a synthetic -carboline alkaloid that has drawn nootropic-community interest for a preclinical property that is genuinely unusual among -carbolines: in rodent and cell-culture studies it appears to stimulate the dopaminergic phenotype - raising tyrosine hydroxylase, the number of differentiated dopamine neurons and dopamine content - while also showing neuroprotective, neurorestorative and anti-inflammatory effects, plus in-vitro MAO-A/MAO-B inhibition [PMID:17913302, PMID:20374418, PMID:32285253].
Aniracetam
NootropicsApproved (Italy)Aniracetam is a pyrrolidinone in the racetam family, developed by Hoffmann-La Roche under the code Ro 13-5057.
Bemethyl (bemitil)
NootropicsApproved (Russia)Bemethyl, known in the Russian literature as bemitil and sold in the region under names including Metaprot, Bemactor and Antihot, is 2-ethylthiobenzimidazole, normally handled as the hydrobromide salt.
Bromantane
NootropicsRussia ApprovedBromantane is an atypical psychostimulant and anxiolytic developed in the 1980s at the Zakusov Institute of Pharmacology of the Russian Academy of Medical Sciences, originally created as an adaptogen for Soviet military and elite athletic use and later approved in Russia for the treatment of neurasthenic and asthenic disorders under the trade name Ladasten.
Cyclazodone
NootropicsPreclinicalCyclazodone is the N-cyclopropyl derivative of pemoline, a 4-oxazolidinone stimulant.
Dihexa
NootropicsPreclinicalDihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University.
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4/21/2026Research Score
0 PubMed results
Quality Indicators
Data Completeness
63%Quick Facts
Half-Life
Approx. 3-8 hours (reported)
Molecular Weight
246.30 g/mol
Administration
Oral
CAS Number
77191-36-7
Trial Phase
Clinical (marketed in Japan; research-use in US)
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is Nefiracetam used for in research?
Nefiracetam (DM-9384) is a fat-soluble pyrrolidone (racetam-class) nootropic research compound developed in Japan and studied for cognitive impairment in cerebrovascular and Alzheimer-type dementia. Unlike water-soluble racetams such as piracetam, its lipophilicity is thought to support good CNS penetration. It is a prescription product in Japan and is sold in the US as a research compound.
What forms does Nefiracetam come in?
Nefiracetam is available in capsule form.
How much does Nefiracetam cost?
Prices start at $44.99 across 1 vendor.
How do I compare Nefiracetam vendors?
Compare prices, payment methods, shipping, and COA scores across 1 vendor.
Research Tools
Related Compounds
View All9-Me-BC (9-Methyl-β-carboline)
NootropicsPreclinical9-Methyl--carboline (9-Me-BC) is a synthetic -carboline alkaloid that has drawn nootropic-community interest for a preclinical property that is genuinely unusual among -carbolines: in rodent and cell-culture studies it appears to stimulate the dopaminergic phenotype - raising tyrosine hydroxylase, the number of differentiated dopamine neurons and dopamine content - while also showing neuroprotective, neurorestorative and anti-inflammatory effects, plus in-vitro MAO-A/MAO-B inhibition [PMID:17913302, PMID:20374418, PMID:32285253].
Aniracetam
NootropicsApproved (Italy)Aniracetam is a pyrrolidinone in the racetam family, developed by Hoffmann-La Roche under the code Ro 13-5057.
Bemethyl (bemitil)
NootropicsApproved (Russia)Bemethyl, known in the Russian literature as bemitil and sold in the region under names including Metaprot, Bemactor and Antihot, is 2-ethylthiobenzimidazole, normally handled as the hydrobromide salt.
Bromantane
NootropicsRussia ApprovedBromantane is an atypical psychostimulant and anxiolytic developed in the 1980s at the Zakusov Institute of Pharmacology of the Russian Academy of Medical Sciences, originally created as an adaptogen for Soviet military and elite athletic use and later approved in Russia for the treatment of neurasthenic and asthenic disorders under the trade name Ladasten.
Cyclazodone
NootropicsPreclinicalCyclazodone is the N-cyclopropyl derivative of pemoline, a 4-oxazolidinone stimulant.
Dihexa
NootropicsPreclinicalDihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University.
Research Benches
Reference pages that put Nefiracetam next to the compounds people pair it with: roles, evidence, overlap and conflicts. No dosing. Research use only.
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