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Kisspeptin-10
Hormones & Endocrine (Non-GH)Phase 2Also known as: Kisspeptin
Kisspeptin-10 is the biologically active 10-amino acid C-terminal fragment of kisspeptin, the endogenous neuropeptide responsible for triggering puberty onset and regulating pulsatile GnRH secretion. Research investigates it for hypogonadotropic hypogonadism, fertility treatments, sexual arousal, and understanding the hypothalamic-pituitary-gonadal axis..
Overview
Key Takeaways
- →LH/FSH stimulation
- →Testosterone support
- →Fertility enhancement
At A Glance
Kisspeptin-10 binds the KISS1R receptor (previously GPR54) on GnRH neurons in the arcuate and anteroventral periventricular nuclei of the hypothalamus, stimulating pulsatile GnRH release. This activates the HPG axis: GnRH → pituitary LH/FSH release → gonadal sex hormone production. It serves as the master regulator of reproductive function, integrating metabolic, circadian, and environmental signals to modulate fertility. Central dopaminergic pathways are also engaged, explaining its effects on sexual motivation.
Kisspeptin-10 binds the KISS1R receptor (previously GPR54) on GnRH neurons in the arcuate and anteroventral periventricular nuclei of the hypothalamus, stimulating pulsatile GnRH release. This activates the HPG axis: GnRH → pituitary LH/FSH release → gonadal sex hormone production. It serves as the master regulator of reproductive function, integrating metabolic, circadian, and environmental signals to modulate fertility. Central dopaminergic pathways are also engaged, explaining its effects on sexual motivation.
Overview
Kisspeptin-10 is the biologically active 10-amino acid C-terminal fragment of kisspeptin, the endogenous neuropeptide responsible for triggering puberty onset and regulating pulsatile GnRH secretion. Research investigates it for hypogonadotropic hypogonadism, fertility treatments, sexual arousal, and understanding the hypothalamic-pituitary-gonadal axis.
Potential Benefits
Potential Research Fields
Chemical Information
IUPAC Name
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
CAS Number
374683-28-0
Molecular Formula
C63H83N17O13
Molecular Mass
1302.46 g/mol
Dosing & Protocols
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Research
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Interactions
Interaction Matrix
Contraindications
Pregnancy or breastfeeding. Known cardiovascular arrhythmias.
Research Disclaimer
This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.
$44.99
$4.4990
1
1
vial
| Vendor | Product | Form | Qty | Price | $/mg | Coupon | |
|---|---|---|---|---|---|---|---|
 |
Kisspeptin-10 10mg | vial | 1 vial● In Stock | $44.99BEST | $4.499 |
Vendors Selling Kisspeptin-10
Related Compounds
View AllGonadorelin
Hormones & Endocrine (Non-GH)
Gonadorelin is a synthetic form of endogenous gonadotropin-releasing hormone (GnRH).
Oxytocin
Hormones & Endocrine (Non-GH)
Oxytocin is a naturally occurring nonapeptide hormone produced in the paraventricular nucleus of the hypothalamus and released from the posterior pituitary.
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Protocols, calculator & safety for Kisspeptin-10
Research Score
591 PubMed studies
Quality Indicators
Data Completeness
88%Research Credibility
Well-researched compound
Quick Facts
Molecular Weight
1302.46 g/mol
CAS Number
374683-28-0
Trial Phase
Phase 2
Safety Profile
Low RiskCommon Side Effects
- • Mild flushing
- • Nausea
- • Headache
- • LH/testosterone surge (expected)
Stop Use If
- Hormone-sensitive cancers
- Pregnancy (outside clinical protocol)
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is Kisspeptin-10 used for in research?
Kisspeptin-10 is the biologically active 10-amino acid C-terminal fragment of kisspeptin, the endogenous neuropeptide responsible for triggering puberty onset and regulating pulsatile GnRH secretion. Research investigates it for hypogonadotropic hypogonadism, fertility treatments, sexual arousal, and understanding the hypothalamic-pituitary-gonadal axis.
What forms does Kisspeptin-10 come in?
Kisspeptin-10 is available in vial form.
How much does Kisspeptin-10 cost?
Prices start at $44.99 across 1 verified vendor.
How do I compare Kisspeptin-10 vendors?
Compare prices, payment methods, shipping, and COA scores across 1 vendor.
Research Tools
Related Compounds
View AllGonadorelin
Hormones & Endocrine (Non-GH)
Gonadorelin is a synthetic form of endogenous gonadotropin-releasing hormone (GnRH).
Oxytocin
Hormones & Endocrine (Non-GH)
Oxytocin is a naturally occurring nonapeptide hormone produced in the paraventricular nucleus of the hypothalamus and released from the posterior pituitary.