Tulsi (Holy Basil) vs Selank
Side-by-side comparison of Tulsi (Holy Basil) and Selank: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Tulsi (Holy Basil)
Selank
Tulsi (Holy Basil)
Tulsi (scientific name Ocimum tenuiflorum, formerly classified as Ocimum sanctum; called tulasi in Sanskrit and most Indian languages, holy basil or sacred basil in Western herbalism, and kala tulsi or manjari for…
No vendor price on file.
Full Tulsi (Holy Basil) profileSelank
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro, 750 Da molecular weight) developed in the 1990s at the Institute of Molecular Genetics of the Russian Academy of Sciences as a synthetic analog of tuftsin…
Lowest listed price: $25.00 across 6 listings
Full Selank profileSide-by-side comparison
| Attribute | Tulsi (Holy Basil) | Selank |
|---|---|---|
| Category | Adaptogen | Nootropics |
| Research Stage | Preclinical | Approved (Russia, as anxiolytic and nootropic medication) |
| Mechanism of Action | Tulsi (Ocimum tenuiflorum) operates through diverse mechanisms reflecting its complex phytochemistry — eugenol, ursolic acid, rosmarinic acid, ocimumosides, flavonoids, and others each contributing distinct activities. The major pharmacologic pathways are… | Primary Mechanism: Multi-System Neurochemical Modulation Selank does not have a single clean receptor-binding mechanism. Unlike benzodiazepines (GABA-A positive allosteric modulators), SSRIs (serotonin reuptake inhibition), or buspirone (5-HT1A partial… |
| Half-Life | — | ~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation) |
| Typical Dose Range | — | 250-750 mcg intranasal daily (0.15% solution: 2-3 drops per nostril 2-3x daily); typical course is 14-21 days |
| Dosing Frequency | — | Intranasal 1–3 times daily |
| Administration | — | Intranasal |
| Side Effects | Tulsi has an excellent safety profile, reflecting thousands of years of food and medicinal use in Indian subcontinent populations. Modern toxicology confirms low toxicity at typical therapeutic doses. Side effects are uncommon and generally mild. Common side… | Overall Safety Profile Selank has one of the best safety profiles in the anxiolytic space. Over 15+ years of Russian clinical use and research, the compound has been associated with essentially no serious adverse events at therapeutic doses. This compares… |
| Molecular Weight | — | 751.9 Da |
| Common Vial Sizes | — | 5mg, 10mg |
Price History
5 data points- OF
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Tulsi (Holy Basil): potential benefits
- No structured benefit list published.
Selank: potential benefits
- Anxiolytic effects comparable to benzodiazepines but without sedation or dependence in Russian clinical trials (PMID: 18454096)
- Positive allosteric modulation of brain GABA receptors through a non-benzodiazepine binding site (PMID: 30255741)
- Immunomodulation via Th1/Th2 cytokine balance and IL-6 regulation in patients with anxiety-asthenic disorders (PMID: 18577961)
- Cognitive and memory support linked to BDNF upregulation in the hippocampus in preclinical models (PMID: 18841804)
- Modulation of the endogenous enkephalin-opioid system supporting mood and stress tolerance (PMID: 22550852)
- Anti-inflammatory and adaptogenic effects through normalization of stress-induced cytokine dysregulation
- Non-addictive anxiolytic profile - no tolerance, withdrawal, or dependence reported across years of Russian clinical use
Frequently asked
What's the difference between Tulsi (Holy Basil) and Selank?
Tulsi (Holy Basil) is a adaptogen that tulsi (ocimum tenuiflorum) operates through diverse mechanisms reflecting its complex phytochemistry — eugenol, ursolic acid, rosmarinic acid, ocimumosides, flavonoids, and others…. Selank is a nootropics that primary mechanism: multi-system neurochemical modulation selank does not have a single clean receptor-binding mechanism. unlike benzodiazepines (gaba-a positive allosteric…. The two differ in mechanism, half-life (not reported vs ~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation)), and typical dose range.
Which has the longer half-life, Tulsi (Holy Basil) or Selank?
Tulsi (Holy Basil) has a half-life of not reported. Selank has a half-life of ~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Tulsi (Holy Basil) and Selank?
Stacking depends on mechanism overlap, safety profile, and goals. Tulsi (Holy Basil) and Selank should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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