SS-31 vs Modafinil
Side-by-side comparison of SS-31 and Modafinil: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
SS-31
Modafinil
SS-31
SS-31 (elamipretide; MTP-131; formerly Bendavia; chemical sequence D-Arg-Dmt-Lys-Phe-NH2 with dimethyltyrosine at position 2) is a first-in-class aromatic-cationic tetrapeptide designed to selectively target the inner…
Lowest listed price: $72.00 across 4 listings
Full SS-31 profileModafinil
Modafinil is a prescription wakefulness-promoting agent approved by the US Food and Drug Administration in December 1998 under the brand name Provigil (Cephalon, now Teva) for the treatment of excessive daytime…
No vendor price on file.
Full Modafinil profileSide-by-side comparison
| Attribute | SS-31 | Modafinil |
|---|---|---|
| Category | Mitochondrial Peptides | Nootropics |
| Research Stage | Clinical/Approved | Preclinical |
| Mechanism of Action | SS-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high concentration of cardiolipin, a signature mitochondrial anionic phospholipid - to… | Modafinil's mechanism of action is genuinely incompletely understood despite more than two decades of clinical use and extensive preclinical research. It is not a classical stimulant — it does not produce the catecholamine surge of amphetamines, the direct… |
| Half-Life | ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding | — |
| Typical Dose Range | 20-60 mg | — |
| Dosing Frequency | Once daily subcutaneous (some protocols use 5-6 days per week) | — |
| Administration | — | — |
| Side Effects | SS-31 (elamipretide) has been generally well-tolerated across clinical trials spanning over a decade of human exposure, with adverse event profiles dominated by injection site reactions rather than systemic toxicity. This favorable safety profile reflects both… | Modafinil's side effect profile is relatively favorable compared to classical stimulants but is not negligible. The most common side effects, reported in 5-10% or more of users in clinical trials, are headache (dose-related, typically transient but… |
| Molecular Weight | 639.8 g/mol | — |
| Common Vial Sizes | — | — |
Price History
2 data points- Ion Peptide
- BHG Labs
Frequently asked
What's the difference between SS-31 and Modafinil?
SS-31 is a mitochondrial peptides that ss-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high…. Modafinil is a nootropics that modafinil's mechanism of action is genuinely incompletely understood despite more than two decades of clinical use and extensive preclinical research. it is not a classical…. The two differ in mechanism, half-life (~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding vs not reported), and typical dose range.
Which has the longer half-life, SS-31 or Modafinil?
SS-31 has a half-life of ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding. Modafinil has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack SS-31 and Modafinil?
Stacking depends on mechanism overlap, safety profile, and goals. SS-31 and Modafinil should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.