PEG-MGF vs Cartalax
Side-by-side comparison of PEG-MGF and Cartalax: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
PEG-MGF
Cartalax
PEG-MGF
PEG-MGF (Pegylated Mechano Growth Factor) is a synthetic, PEGylated form of Mechano Growth Factor (MGF) — an alternatively spliced variant of IGF-1 produced locally in muscle and other tissues in response to mechanical…
Lowest listed price: $39.00 across 1 listing
Full PEG-MGF profileCartalax
Cartalax is a short synthetic peptide developed in Russia by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology, positioned as a "cartilage bioregulator" intended to…
Lowest listed price: $58.85 across 3 listings
Full Cartalax profileSide-by-side comparison
| Attribute | PEG-MGF | Cartalax |
|---|---|---|
| Category | Performance | Recovery |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | PEG-MGF is the PEGylated form of Mechano Growth Factor (MGF), a synthetic peptide corresponding to the C-terminal 24 amino acids of the unique E-domain of IGF-1Ec, an alternatively spliced variant of the IGF-1 gene expressed in skeletal muscle after mechanical… | Mechanism of Action Cartalax's proposed mechanism is the Khavinson short-peptide framework applied to cartilage: passive membrane permeation, nuclear import, and sequence-selective chromatin modulation producing chondrocyte-favourable transcriptional shifts.… |
| Half-Life | Native MGF: very short (minutes) due to rapid proteolysis. PEG-MGF: PEGylation is intended to extend this substantially (community estimates up to roughly 1 day), but there are no published human pharmacokinetic data to confirm a specific value. | No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured. |
| Typical Dose Range | 200 mcg | 20 mg oral/sublingual once daily for 10 days; 60-90 day washout |
| Dosing Frequency | twice_weekly | Once daily |
| Administration | Subcutaneous, Intramuscular, Intravenous | — |
| Side Effects | — | Side Effects and Safety Cartalax has been used in Russian clinical settings for roughly 20 years with a sparse adverse-event literature — reassuring in direction, insufficient for confident pharmacovigilance. Reported short-term adverse effects -… |
| Molecular Weight | Free MGF 24-aa peptide: approximately 2,867-2,868 Da (reported molecular formula ~C121H199N41O40). PEG-MGF is heavier: the conjugated polyethylene glycol adds a variable mass (commonly a few kDa) on top of the peptide, so total mass depends on the PEG used. | 333.29 g/mol |
| Common Vial Sizes | 2 | — |
Price tracking
Price History
3 data points- Ion Peptide
- Disguised Alpha
- LB
PEG-MGF: potential benefits
- Increases satellite-cell and myoblast proliferation, expanding the cell pool available for muscle repair (in vitro and animal studies)
- May accelerate muscle repair after exercise-induced damage or injury (preclinical)
- Pro-survival, anti-apoptotic signaling reported in muscle and other cell types (preclinical)
- Preclinical cytoprotection: MGF pretreatment improved cardiac function after experimental myocardial infarction (mechanism distinct from IGF-1R, NOT via fibroblast growth factor receptor)
- Preclinical neuroprotection during cerebral ischemia
- PEGylation is intended to extend native MGF's very short half-life to allow less frequent research dosing
Cartalax: potential benefits
- Joint and cartilage repair support
- Connective tissue maintenance
- Anti-aging effects on musculoskeletal system
- Improved joint mobility
Frequently asked
What's the difference between PEG-MGF and Cartalax?
PEG-MGF is a performance that peg-mgf is the pegylated form of mechano growth factor (mgf), a synthetic peptide corresponding to the c-terminal 24 amino acids of the unique e-domain of igf-1ec, an alternatively…. Cartalax is a recovery that mechanism of action cartalax's proposed mechanism is the khavinson short-peptide framework applied to cartilage: passive membrane permeation, nuclear import, and sequence-selective…. The two differ in mechanism, half-life (Native MGF: very short (minutes) due to rapid proteolysis. PEG-MGF: PEGylation is intended to extend this substantially (community estimates up to roughly 1 day), but there are no published human pharmacokinetic data to confirm a specific value. vs No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured.), and typical dose range.
Which has the longer half-life, PEG-MGF or Cartalax?
PEG-MGF has a half-life of Native MGF: very short (minutes) due to rapid proteolysis. PEG-MGF: PEGylation is intended to extend this substantially (community estimates up to roughly 1 day), but there are no published human pharmacokinetic data to confirm a specific value.. Cartalax has a half-life of No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, PEG-MGF or Cartalax?
Lowest listed price on BodyHackGuide: PEG-MGF from $39.00, Cartalax from $58.85. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack PEG-MGF and Cartalax?
Stacking depends on mechanism overlap, safety profile, and goals. PEG-MGF and Cartalax should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Listings from the vendors we track. Prices change often, so check the vendor before you buy.
Before you buy PEG-MGF or Cartalax
Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor.
Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.