Lipo-C vs Tesofensine
Side-by-side comparison of Lipo-C and Tesofensine: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Lipo-C
Tesofensine
Lipo-C
Lipo-C (also sold as a MIC or "lipotropic" injection) is a compounded blend of methionine, inositol, and choline, usually with vitamin B12 and sometimes L-carnitine, marketed by medspas and weight-loss clinics to support…
Lowest listed price: $54.99 across 2 listings
Full Lipo-C profileTesofensine
Tesofensine (NS2330) is an orally-administered small-molecule triple monoamine reuptake inhibitor — it blocks the reuptake of noradrenaline, dopamine, and serotonin, placing it in the same broad pharmacologic class as…
Lowest listed price: $79.99 across 2 listings
Full Tesofensine profileSide-by-side comparison
| Attribute | Lipo-C | Tesofensine |
|---|---|---|
| Category | Weight Loss | Weight Loss |
| Research Stage | No clinical trials of the blend (marketed compounded injection) | Preclinical |
| Mechanism of Action | Lipo-C is a "lipotropic" injection built on the MIC base, methionine, inositol, and choline, usually combined with vitamin B12 and sometimes L-carnitine. The rationale is borrowed from classic nutritional biochemistry: choline and methionine are methyl donors… | Tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. By inhibiting the neurotransmitter transporters (NET, DAT, and SERT respectively), tesofensine raises synaptic… |
| Half-Life | Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted. | — |
| Typical Dose Range | 1 mL of a compounded MIC blend intramuscularly, 1 to 2x per week. No standardized dose exists; concentrations vary by compounding pharmacy. | 0.25 mg - 1 mg daily (oral) |
| Dosing Frequency | 1 to 2 times per week (intramuscular; occasionally subcutaneous) | — |
| Administration | — | — |
| Side Effects | Injection-site pain, stinging, or redness; mild nausea; transient diarrhea or loose stools; headache. Less common: dizziness, allergic reaction, or a transient fishy body odor from high choline intake (trimethylamine). The risk profile of any compounded… | Tesofensine's side effect profile reflects its monoamine-enhancing mechanism. Most effects are predictable extensions of NE, DA, and 5-HT elevation. The cardiovascular profile is the dominant clinical concern and the primary reason regulators have not approved… |
| Molecular Weight | — | 298.24 g/mol |
| Common Vial Sizes | — | — |
Price History
2 data points- OF
- Disguised Alpha
Price tracking
Lipo-C: potential benefits
- Supplies choline and methionine, methyl donors the liver uses to package and export triglycerides (most relevant when dietary intake is low) [PMID:30681159]
- Provides inositol, which improved ovarian function and produced modest weight loss versus placebo in a randomized trial in women with PCOS [PMID:15206484]
- When L-carnitine is included, adds a cofactor for shuttling fatty acids into mitochondria; oral carnitine yields a modest average weight reduction in meta-analyses [PMID:32359762]
- B12 (when included) supports energy and red-cell metabolism, but relieves fatigue only when a genuine deficiency is present
- May help correct sub-optimal choline status, which is associated with a higher risk of hepatic steatosis [PMID:37513629]
- Popular anecdotally as an energy 'kickstart' adjunct to a calorie-controlled diet, though these effects are subjective and unproven
Tesofensine: potential benefits
- Significant weight loss (10-15% body weight)
- Appetite suppression
- Increased metabolic rate
- Enhanced dopamine-driven motivation
Frequently asked
What's the difference between Lipo-C and Tesofensine?
Lipo-C is a weight loss that lipo-c is a "lipotropic" injection built on the mic base, methionine, inositol, and choline, usually combined with vitamin b12 and sometimes l-carnitine. the rationale is borrowed…. Tesofensine is a weight loss that tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. by inhibiting the neurotransmitter…. The two differ in mechanism, half-life (Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted. vs not reported), and typical dose range.
Which has the longer half-life, Lipo-C or Tesofensine?
Lipo-C has a half-life of Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted.. Tesofensine has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, Lipo-C or Tesofensine?
Lowest listed price on BodyHackGuide: Lipo-C from $54.99, Tesofensine from $79.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack Lipo-C and Tesofensine?
Stacking depends on mechanism overlap, safety profile, and goals. Lipo-C and Tesofensine should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Before you buy Lipo-C or Tesofensine
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Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks, and every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.