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    Lipo-C

    Weight LossNo clinical trials of the blend (marketed compounded injection)

    Also known as: L-Carnitine MIC ATP, MIC + ATP, Lipotropic Injection, Lipolytic Blend, Lipo Fat Burner Blend, Lipo Fat Burner, MIC injection, Optimum Lipolytic, Optimum Lipolytic Research Blend

    Lipo-C (also sold as a MIC or "lipotropic" injection) is a compounded blend of methionine, inositol, and choline, usually with vitamin B12 and sometimes L-carnitine, marketed by medspas and weight-loss clinics to support fat metabolism and energy. The individual nutrients have real, defined metabolic roles and some modest human data, but almost all of that evidence is from oral or dietary intake, and the injectable blend itself has no clinical trials demonstrating fat loss.

    OF

    Featured vendor

    $89.991 x 20mL multi-dose vial

    at Optimum Formula ·

    Buy at OF
    Half-life: Not applicable to the blend
    Last reviewed:

    Overview

    At A Glance

    Mechanism

    Lipo-C is a "lipotropic" injection built on the MIC base, methionine, inositol, and choline, usually combined with vitamin B12 and sometimes L-carnitine. The rationale is borrowed from classic nutritional biochemistry: choline and methionine are methyl donors the liver uses to sy…

    Half-Life
    Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted.
    Dosing
    1 to 2 times per week (intramuscular; occasionally subcutaneous)
    Dose Range
    1 mL of a compounded MIC blend intramuscularly, 1 to 2x per week. No standardized dose exists; concentrations vary by compounding pharmacy.
    Potential Benefits
    Supplies choline and methionine, methyl donors the liver uses to package and export triglycerides (most relevant when dietary intake is low) [PMID:30681159]Provides inositol, which improved ovarian function and produced modest weight loss versus placebo in a randomized trial in women with PCOS [PMID:15206484]When L-carnitine is included, adds a cofactor for shuttling fatty acids into mitochondria; oral carnitine yields a modest average weight reduction in meta-analyses [PMID:32359762]B12 (when included) supports energy and red-cell metabolism, but relieves fatigue only when a genuine deficiency is presentMay help correct sub-optimal choline status, which is associated with a higher risk of hepatic steatosis [PMID:37513629]Popular anecdotally as an energy 'kickstart' adjunct to a calorie-controlled diet, though these effects are subjective and unproven
    Safety Notes
    Common
    Injection-site pain or redness, mild nausea, transient diarrhea, headache.

    Mechanism of Action

    Lipo-C is a "lipotropic" injection built on the MIC base, methionine, inositol, and choline, usually combined with vitamin B12 and sometimes L-carnitine. The rationale is borrowed from classic nutritional biochemistry: choline and methionine are methyl donors the liver uses to synthesize phosphatidylcholine and package triglycerides into VLDL for export, so a deficiency in either causes fat to accumulate in the liver [PMID:30681159][PMID:23305254]. Inositol participates in insulin signaling and cellular lipid handling, and carnitine shuttles long-chain fatty acids into mitochondria for beta-oxidation. B12 is a cofactor for regenerating methionine and for red-cell and energy metabolism. The marketing leap is the assumption that injecting these nutrients into an already well-nourished person will accelerate whole-body fat loss. That step is not supported: the lipotropic mechanism prevents or reverses fat accumulation under deficiency, but no trial shows it strips fat from people who are already nutrient-replete. Any real-world weight loss on a Lipo-C protocol comes from the accompanying calorie deficit, not the injection. Research Use Only.

    Overview

    Lipo-C (also sold as a MIC or "lipotropic" injection) is a compounded blend of methionine, inositol, and choline, usually with vitamin B12 and sometimes L-carnitine, marketed by medspas and weight-loss clinics to support fat metabolism and energy. The individual nutrients have real, defined metabolic roles and some modest human data, but almost all of that evidence is from oral or dietary intake, and the injectable blend itself has no clinical trials demonstrating fat loss. Covered here for research and harm-reduction context only. Research Use Only.

    What to Expect

    • •There is no clinical trial of the Lipo-C / MIC injection itself, so any effect on body weight is unproven and small at best.
    • •Most people notice nothing dramatic; reported effects on energy or appetite are subjective and heavily shaped by the accompanying diet and calorie deficit.
    • •Any meaningful fat loss comes from the calorie deficit and exercise the injection is paired with, not from the injection alone.
    • •If a B12-containing formula is used and you were genuinely deficient, you may notice improved energy; if you were already replete, expect no energy change.
    • •Injection-site stinging or redness and mild, short-lived nausea or loose stools are the most common actual experiences.

    Individual responses vary. Timeline based on commonly reported research observations.

    Chemical Information

    IUPAC Name

    Not yet available

    CAS Number

    Not yet available

    Molecular Formula

    Blend

    Molecular Mass

    Not yet available

    Dosing & Protocols

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    Research

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    • A summary of the key research
    • Safety and side effects
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    Interactions

    Interaction Matrix

    Contraindications

    Known allergy to any component (especially B-vitamins or cobalt/cobalamin). Active liver or kidney disease. Leber's hereditary optic neuropathy (cyanocobalamin-containing formulas can accelerate vision loss). Pregnancy or breastfeeding. Involve a clinician if you have trimethylaminuria (fish-odor disorder) or take methotrexate or other folate/methyl-pathway drugs.

    Research Disclaimer

    This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.

    Best Price

    $54.99

    up to $89.99

    Best $/mg

    —

    Vendors

    2

    Listings

    2

    liquid, blend

    Form
    Sort
    Vendor Product Form Qty Price $/mg Coupon
    🔬
    Optimum Formula
    100
    🇺🇸US
    Optimum Lipolytic Research Blend (L-Carnitine + MIC + ATP) 20mL blend 1 x 20mL multi-dose vial● In Stock $89.99 —
    Disguised Alpha logo
    Disguised Alpha
    50
    🇺🇸US🇪🇺EU🇬🇧UK
    Lipo-C + B Vitamins liquid 1 vial● In Stock $54.99BEST — —

    Sign in to leave a review

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    Current low
    $54.99
    current listings
    7-day low
    —
    not enough history yet
    30-day low
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    not enough history yet
    30-day change
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    not enough history yet

    Tracking since May 28, 2026 · 2 data points

    Price History

    2 data points
    • OF
    • Disguised Alpha

    Vendors Selling Lipo-C

    How we score these vendors

    Every supplier above is graded 0 to 100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank.

    View Scorecard

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    View Full Dosage Guide →

    Protocols, calculator & safety for Lipo-C

    Featured Price

    🔬

    Optimum Formula

    $89.99

    2 vendors · 2 listings

    Research Score

    60

    0 PubMed results

    Quality Indicators

    Data Completeness

    88%
    Description
    Mechanism of Action
    Chemical Data
    Dosing Protocols
    Safety Profile
    PubMed Results
    Interactions
    Vendor Listings

    COA Verification

    4

    Verified COAs

    2

    Vendors w/ COA

    Latest test: 9/16/2026

    Quick Facts

    Half-Life

    Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted.

    Trial Phase

    No clinical trials of the blend (marketed compounded injection)

    Safety Profile

    Common Side Effects

    • • Injection-site pain or redness, mild nausea, transient diarrhea, headache.

    Research Disclaimer

    This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.

    Frequently Asked Questions

    What is Lipo-C?

    Lipo-C is a compounded 'lipotropic' injection built on the MIC base: methionine, inositol, and choline, usually with vitamin B12 and sometimes L-carnitine. Medspas and compounding pharmacies market it as a fat-metabolism or energy 'boost.' It is not an FDA-approved drug and is covered here for research context only.

    Does Lipo-C actually burn fat?

    There is no clinical trial of the injection showing it burns fat. The lipotropic idea is extrapolated from the fact that choline and methionine prevent fat build-up in the liver under deficiency. In a well-nourished person, any weight loss on a Lipo-C protocol comes from the diet and calorie deficit it is paired with, not the shot.

    What is actually in it?

    The core is methionine, inositol, and choline (MIC). Most formulas add vitamin B12 (cyanocobalamin or methylcobalamin), and some add L-carnitine, a B-complex (B1/B2/B5/B6), or L-arginine. Concentrations vary widely by pharmacy because there is no standardized formula.

    How is this different from just taking oral choline, inositol, or carnitine?

    Mechanistically it delivers the same nutrients by injection instead of by mouth. The human evidence that exists (modest weight signals for inositol and carnitine, liver-fat effects for choline) is almost all from oral dosing. No study has shown the injection outperforms an adequate diet or oral supplementation.

    Is it safe?

    The individual nutrients are water-soluble and generally low-toxicity at supplemental doses, with excess mostly excreted. The most common effects are injection-site stinging or redness, mild nausea, loose stools, and headache. The real-world risk with any compounded injectable is product quality: sterility and accurate labeling depend entirely on the source.

    Is Lipo-C FDA-approved?

    No. It is not an approved drug. Its ingredients are dietary nutrients supplied through compounding pharmacies. BodyHackGuide covers it for research and harm-reduction context only, not as medical advice.

    Can I use it alongside semaglutide or tirzepatide?

    It is often stacked with GLP-1 medications at weight-loss clinics, but there is no interaction or added-benefit data for the combination. Any meaningful fat loss in that stack is driven by the GLP-1 drug and the diet, not the lipotropic blend.

    How many vendors sell Lipo-C, and what does it cost per mg?

    2 of the vendors BodyHackGuide tracks list Lipo-C (2 listings). The lowest listed price BodyHackGuide has recorded for Lipo-C is $54.99. No Lipo-C listing recorded as in stock carries a milligram count, so BodyHackGuide states no price per milligram for Lipo-C.

    Which vendors have third-party COAs for Lipo-C on file at BodyHackGuide?

    BodyHackGuide holds 10 third-party certificate records for Lipo-C, from . No editor has read any of BodyHackGuide's 10 certificate records for Lipo-C. The laboratory named on BodyHackGuide's Lipo-C certificate records is Freedom Diagnostics Testing, and the newest test date on them is 10 August 2026. Each vendor page on BodyHackGuide shows how many certificate records BodyHackGuide holds for that vendor and links to each record that has its own page.

    Research Tools

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    View All

    5-Amino-1MQ

    Weight LossPreclinical

    5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to form 1-methylnicotinamide (1-MNA) and S-adenosyl-L-homocysteine (SAH).

    t½ ~6–12 hours (oral) 50 mg - 150 mg daily (oral or injection)
    PreclinicalView Profile

    Adipotide

    Weight LossPhase 1

    Adipotide is an experimental chimeric peptide that joins a white-fat-homing motif to a cell-killing motif, developed in the laboratory of Wadih Arap and Renata Pasqualini to destroy the blood supply of white adipose tissue.

    t½ No published human value. The first-in-human trial planned pharmacokinetic sampling at 10 minutes, 30 minutes, 1 hour and 4 hours after dosing but was terminated with no results posted (ClinicalTrials.gov NCT01262664). The monkey studies used daily subcutaneous dosing chosen by body surface area scaling rather than from a measured half-life (PMID: 22072637)
    PreclinicalView Profile

    BAM15

    Weight LossPreclinical

    BAM15 is a small-molecule mitochondrial protonophore uncoupler that was first described in 2014 as a tool compound for dissipating proton motive force selectively across the inner mitochondrial membrane without collapsing the plasma membrane electrochemical gradient ([Kenwood et al., 2014]).

    Research compound — no established human doses. Animal studies use 10-100 mg/kg
    58 PubMedView Profile

    Eloralintide (LY3841136)

    Weight LossPhase 3

    Eloralintide is an amylin analog developed by Eli Lilly and Company for weight management, given as a once-weekly subcutaneous injection.

    t½ Terminal geometric mean half-life 310 to 366 hours, that is 12.9 to 15.3 days, across the doses tested in the phase 1 single-ascending-dose study in humans (PMID: 41109426)
    PreclinicalView Profile

    Exenatide

    Weight LossFDA-approved

    Exenatide (Byetta, Bydureon) is a synthetic exendin-4 GLP-1 receptor agonist, FDA-approved for type 2 diabetes, that lowers blood glucose and curbs appetite.

    t½ Immediate-release (Byetta): terminal half-life about 2.4 hours, cleared mainly by the kidneys. Extended-release (Bydureon): the same peptide is released slowly from biodegradable microspheres over roughly 10 weeks, reaching steady-state plasma levels by about 6 to 7 weeks. 5 to 10 mcg twice daily (Byetta, immediate-release) or 2000 mcg (2 mg) once weekly (Bydureon, extended-release)
    PreclinicalView Profile

    L-Carnitine

    Weight LossPreclinical

    L-Carnitine is a naturally occurring quaternary ammonium compound synthesized in the body from the amino acids lysine and methionine, with essential cofactor roles in fatty acid metabolism, energy production, and cellular health.

    500 mg - 2000 mg daily (oral or injection)
    4,002 PubMedView Profile

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