Lipo-C vs 5-Amino-1MQ
Side-by-side comparison of Lipo-C and 5-Amino-1MQ: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Lipo-C
5-Amino-1MQ
Lipo-C
Lipo-C (also sold as a MIC or "lipotropic" injection) is a compounded blend of methionine, inositol, and choline, usually with vitamin B12 and sometimes L-carnitine, marketed by medspas and weight-loss clinics to support…
Lowest listed price: $54.99 across 2 listings
Full Lipo-C profile5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to…
Lowest listed price: $29.99 across 14 listings
Full 5-Amino-1MQ profileSide-by-side comparison
| Attribute | Lipo-C | 5-Amino-1MQ |
|---|---|---|
| Category | Weight Loss | Weight Loss |
| Research Stage | No clinical trials of the blend (marketed compounded injection) | Preclinical |
| Mechanism of Action | Lipo-C is a "lipotropic" injection built on the MIC base, methionine, inositol, and choline, usually combined with vitamin B12 and sometimes L-carnitine. The rationale is borrowed from classic nutritional biochemistry: choline and methionine are methyl donors… | 5-Amino-1MQ works by inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to the nitrogen of nicotinamide (vitamin B3 amide), producing 1-methylnicotinamide (1-MNA) and… |
| Half-Life | Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted. | ~6–12 hours (oral) |
| Typical Dose Range | 1 mL of a compounded MIC blend intramuscularly, 1 to 2x per week. No standardized dose exists; concentrations vary by compounding pharmacy. | 50 mg - 150 mg daily (oral or injection) |
| Dosing Frequency | 1 to 2 times per week (intramuscular; occasionally subcutaneous) | Once daily oral |
| Administration | — | Oral |
| Side Effects | Injection-site pain, stinging, or redness; mild nausea; transient diarrhea or loose stools; headache. Less common: dizziness, allergic reaction, or a transient fishy body odor from high choline intake (trimethylamine). The risk profile of any compounded… | The side effect profile of 5-amino-1MQ in humans is not documented because there are no human clinical trials. Rodent studies report generally good tolerability at doses producing metabolic and muscle benefits, without obvious signs of hepatotoxicity,… |
| Molecular Weight | — | 159.21 g/mol |
| Common Vial Sizes | — | 50mg capsules, 100mg capsules |
Price History
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Lipo-C: potential benefits
- Supplies choline and methionine, methyl donors the liver uses to package and export triglycerides (most relevant when dietary intake is low) [PMID:30681159]
- Provides inositol, which improved ovarian function and produced modest weight loss versus placebo in a randomized trial in women with PCOS [PMID:15206484]
- When L-carnitine is included, adds a cofactor for shuttling fatty acids into mitochondria; oral carnitine yields a modest average weight reduction in meta-analyses [PMID:32359762]
- B12 (when included) supports energy and red-cell metabolism, but relieves fatigue only when a genuine deficiency is present
- May help correct sub-optimal choline status, which is associated with a higher risk of hepatic steatosis [PMID:37513629]
- Popular anecdotally as an energy 'kickstart' adjunct to a calorie-controlled diet, though these effects are subjective and unproven
5-Amino-1MQ: potential benefits
- Enhanced fat metabolism and weight loss
- Increased NAD+ levels in adipose tissue
- Improved cellular energy production
- Anti-aging properties via sirtuin activation
Frequently asked
What's the difference between Lipo-C and 5-Amino-1MQ?
Lipo-C is a weight loss that lipo-c is a "lipotropic" injection built on the mic base, methionine, inositol, and choline, usually combined with vitamin b12 and sometimes l-carnitine. the rationale is borrowed…. 5-Amino-1MQ is a weight loss that 5-amino-1mq works by inhibiting nicotinamide n-methyltransferase (nnmt), an enzyme that catalyzes the transfer of a methyl group from s-adenosyl-l-methionine (sam) to the nitrogen…. The two differ in mechanism, half-life (Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted. vs ~6–12 hours (oral)), and typical dose range.
Which has the longer half-life, Lipo-C or 5-Amino-1MQ?
Lipo-C has a half-life of Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted.. 5-Amino-1MQ has a half-life of ~6–12 hours (oral). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, Lipo-C or 5-Amino-1MQ?
Lowest listed price on BodyHackGuide: Lipo-C from $54.99, 5-Amino-1MQ from $29.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack Lipo-C and 5-Amino-1MQ?
Stacking depends on mechanism overlap, safety profile, and goals. Lipo-C and 5-Amino-1MQ should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks, and every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.