KPV vs Pinealon
Side-by-side comparison of KPV and Pinealon: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
KPV
Pinealon
KPV
KPV is a three-amino-acid peptide — Lysine-Proline-Valine — that makes up the C-terminal tail of alpha-MSH (alpha-melanocyte-stimulating hormone). With a molecular weight of only 342.4 Da, it is one of the smallest…
Lowest listed price: $34.99 across 8 listings
Full KPV profilePinealon
Pinealon is a synthetic tripeptide — glutamyl-aspartyl-arginine (Glu-Asp-Arg, or EDR) — developed by the St Petersburg Institute of Bioregulation and Gerontology (IBG) under the leadership of Professor Vladimir…
Lowest listed price: $45.00 across 3 listings
Full Pinealon profileSide-by-side comparison
| Attribute | KPV | Pinealon |
|---|---|---|
| Category | Recovery | Nootropics |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | KPV's mechanism of action has been worked out in detail over the past 20 years, and it is unusual enough to be worth understanding if you are using this compound. Unlike most peptides, KPV does not primarily act through classical G-protein-coupled receptors on… | The proposed mechanism of Pinealon is rooted in the Khavinson school's broader theory of short-peptide tissue-specific bioregulation. The full theory is worth understanding because it underlies all twelve Russian bioregulator compounds in this catalog. The… |
| Half-Life | ~15–30 minutes (short-lived but downstream anti-inflammatory effects persist) | Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing. |
| Typical Dose Range | 500 mcg-2 mg per dose (standard); up to 5 mg daily in advanced protocols | Subcutaneous (primary route): 2-10 mg/day, typically 3-5 mg, in pulsed 10-20 day cycles, 2-4 cycles/year. Intranasal: 150-800 mcg per nostril daily. Research use only; oral dosing is not recommended because the peptide is largely degraded by GI proteases. |
| Dosing Frequency | Once daily subcutaneous or oral | Once daily during a cycle (morning preferred); some advanced users split into AM + midday doses. Not dosed continuously year-round - cycles are pulsed. |
| Administration | Subcutaneous, Oral, Topical | — |
| Side Effects | KPV's side effect profile, based on the published literature and the research-peptide community's accumulated experience, is notable primarily for what is NOT reported. Across preclinical studies and the limited human case reports, no serious adverse events… | The side-effect profile of Pinealon, based on the available Russian clinical literature and user-reported experience, is described as mild and uncommon. Whether this reflects genuinely low toxicity or inadequate reporting in the available studies is a… |
| Molecular Weight | 342.43 g/mol | 418.40 g/mol (C15H26N6O8) |
| Common Vial Sizes | 5mg, 10mg | — |
Price History
5 data points- OF
- BM
- Half Nattys
- Ion Peptide
- Disguised Alpha
- BHG Labs
Price History
2 data points- Ion Peptide
- Disguised Alpha
KPV: potential benefits
- Potent anti-inflammatory effects
- Gut healing and barrier repair
- Antimicrobial properties
- Skin wound healing support
- Potential anti-cancer properties (anti-angiogenic in tumors)
Pinealon: potential benefits
- Neuroprotection against oxidative and hypoxic stress (preclinical models)
- Antioxidant support - reduced oxidative DNA damage in aged neurons (in vitro)
- Cognitive and memory support in aging populations (small Russian clinical reports)
- Reduced neuronal apoptosis and support of dendritic-tree integrity in cell models
- Investigated for neuroprotection in Alzheimer's-model systems (preclinical)
Frequently asked
What's the difference between KPV and Pinealon?
KPV is a recovery that kpv's mechanism of action has been worked out in detail over the past 20 years, and it is unusual enough to be worth understanding if you are using this compound. unlike most…. Pinealon is a nootropics that the proposed mechanism of pinealon is rooted in the khavinson school's broader theory of short-peptide tissue-specific bioregulation. the full theory is worth understanding because…. The two differ in mechanism, half-life (~15–30 minutes (short-lived but downstream anti-inflammatory effects persist) vs Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing.), and typical dose range.
Which has the longer half-life, KPV or Pinealon?
KPV has a half-life of ~15–30 minutes (short-lived but downstream anti-inflammatory effects persist). Pinealon has a half-life of Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, KPV or Pinealon?
Lowest listed price on BodyHackGuide: KPV from $34.99, Pinealon from $45.00. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack KPV and Pinealon?
Stacking depends on mechanism overlap, safety profile, and goals. KPV and Pinealon should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Listings from the vendors we track. Prices change often, so check the vendor before you buy.
Before you buy KPV or Pinealon
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.