Eleuthero vs SS-31
Side-by-side comparison of Eleuthero and SS-31: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Eleuthero
SS-31
Eleuthero
Eleuthero (scientific name Eleutherococcus senticosus, formerly classified as Acanthopanax senticosus; called ci wu jia in Chinese, siberian ginseng in Western herbalism — though this common name is problematic and…
No vendor price on file.
Full Eleuthero profileSS-31
SS-31 (elamipretide; MTP-131; formerly Bendavia; chemical sequence D-Arg-Dmt-Lys-Phe-NH2 with dimethyltyrosine at position 2) is a first-in-class aromatic-cationic tetrapeptide designed to selectively target the inner…
Lowest listed price: $72.00 across 4 listings
Full SS-31 profileSide-by-side comparison
| Attribute | Eleuthero | SS-31 |
|---|---|---|
| Category | Adaptogen | Mitochondrial Peptides |
| Research Stage | Preclinical | Clinical/Approved |
| Mechanism of Action | Eleuthero (Eleutherococcus senticosus) operates through multiple adaptogenic mechanisms, most of which fall under the broad concept of stress-system normalization and cellular resilience enhancement. Unlike simple stimulants that acutely upregulate one… | SS-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high concentration of cardiolipin, a signature mitochondrial anionic phospholipid - to… |
| Half-Life | — | ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding |
| Typical Dose Range | — | 20-60 mg |
| Dosing Frequency | — | Once daily subcutaneous (some protocols use 5-6 days per week) |
| Administration | — | — |
| Side Effects | Eleuthero has one of the best safety profiles among classical adaptogens, with thousands of human subjects studied across Russian and Western research and very low incidence of serious adverse effects. Most users tolerate standard doses (300-1200mg extract… | SS-31 (elamipretide) has been generally well-tolerated across clinical trials spanning over a decade of human exposure, with adverse event profiles dominated by injection site reactions rather than systemic toxicity. This favorable safety profile reflects both… |
| Molecular Weight | — | 639.8 g/mol |
| Common Vial Sizes | — | — |
Price History
2 data points- Ion Peptide
- BHG Labs
Frequently asked
What's the difference between Eleuthero and SS-31?
Eleuthero is a adaptogen that eleuthero (eleutherococcus senticosus) operates through multiple adaptogenic mechanisms, most of which fall under the broad concept of stress-system normalization and cellular…. SS-31 is a mitochondrial peptides that ss-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high…. The two differ in mechanism, half-life (not reported vs ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding), and typical dose range.
Which has the longer half-life, Eleuthero or SS-31?
Eleuthero has a half-life of not reported. SS-31 has a half-life of ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Eleuthero and SS-31?
Stacking depends on mechanism overlap, safety profile, and goals. Eleuthero and SS-31 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks, and every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.