Cortagen vs Coenzyme Q10
Side-by-side comparison of Cortagen and Coenzyme Q10: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Cortagen
Coenzyme Q10
Cortagen
Cortagen is a synthetic tetrapeptide, Ala-Glu-Asp-Pro (AEDP), made at Vladimir Khavinson's St. Petersburg Institute of Bioregulation and Gerontology from the amino acid analysis of Cortexin, a peptide preparation from…
Lowest listed price: $79.00 across 1 listing
Full Cortagen profileCoenzyme Q10
Coenzyme Q10 (CoQ10), also known as ubiquinone-10, ubidecarenone, or simply "coenzyme Q," is a lipid-soluble benzoquinone compound with a 50-carbon isoprenoid side chain (decaprenyl tail) that anchors it within the inner…
Lowest listed price: $74.99 across 1 listing
Full Coenzyme Q10 profileSide-by-side comparison
| Attribute | Cortagen | Coenzyme Q10 |
|---|---|---|
| Category | Longevity | Foundational |
| Research Stage | Preclinical | Dietary Supplement (Food Ingredient) |
| Mechanism of Action | Cortagen is a synthetic tetrapeptide, Ala-Glu-Asp-Pro (AEDP), created by the Khavinson group through directed synthesis based on the amino-acid composition of Cortexin, a polypeptide complex extracted from the cerebral cortex [PMID:15159690]. It is a… | Coenzyme Q10 operates through two mechanistically distinct functions — electron transport in oxidative phosphorylation and lipid-phase antioxidant defense — that together make it arguably the most important single molecule for cellular energy and membrane… |
| Half-Life | Unknown (tetrapeptide; estimated <4 hours) | — |
| Typical Dose Range | — | — |
| Dosing Frequency | once_daily | — |
| Administration | Subcutaneous, Intramuscular | — |
| Side Effects | — | Coenzyme Q10 has an exceptional safety profile across decades of clinical use, including the Q-SYMBIO trial population (NYHA III-IV heart failure, mean age 63) where no safety signals emerged over two years of high-dose therapy. Side effects are uncommon,… |
| Molecular Weight | 430.4 g/mol (C17H26N4O9, PubChem CID 18439621) | — |
| Common Vial Sizes | 20 | — |
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Cortagen: potential benefits
- Peripheral nerve repair - accelerated axon regeneration and faster nerve-conduction recovery after injury in rat models [PMID:11276314; PMID:12134478]
- Neuroprotection and antioxidant activity in the cerebral cortex and in chronic brain-ischemia models (preclinical) [PMID:18239817; PMID:21476278]
- CNS/cognitive support as the synthetic short-peptide analog of the cortex-derived Russian drug Cortexin
- Anti-aging chromatin remodeling - reactivation of age-silenced ribosomal genes in lymphocytes from elderly donors [PMID:15085253; PMID:37042594]
- Mild immune-signaling modulation (IL-2 expression), generally weaker than Vilon or Epithalon [PMID:12447482; PMID:16224591]
- Longevity-protocol stacking as one of the Khavinson short-peptide bioregulators (commonly paired with Epitalon or Pinealon)
Coenzyme Q10: potential benefits
- No structured benefit list published.
Frequently asked
What's the difference between Cortagen and Coenzyme Q10?
Cortagen is a longevity that cortagen is a synthetic tetrapeptide, ala-glu-asp-pro (aedp), created by the khavinson group through directed synthesis based on the amino-acid composition of cortexin, a…. Coenzyme Q10 is a foundational that coenzyme q10 operates through two mechanistically distinct functions — electron transport in oxidative phosphorylation and lipid-phase antioxidant defense — that together make it…. The two differ in mechanism, half-life (Unknown (tetrapeptide; estimated <4 hours) vs not reported), and typical dose range.
Which has the longer half-life, Cortagen or Coenzyme Q10?
Cortagen has a half-life of Unknown (tetrapeptide; estimated <4 hours). Coenzyme Q10 has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, Cortagen or Coenzyme Q10?
Lowest listed price on BodyHackGuide: Cortagen from $79.00, Coenzyme Q10 from $74.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack Cortagen and Coenzyme Q10?
Stacking depends on mechanism overlap, safety profile, and goals. Cortagen and Coenzyme Q10 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Listings from the vendors we track. Prices change often, so check the vendor before you buy.
Before you buy Cortagen or Coenzyme Q10
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.