Clascoterone vs Snap-8
Side-by-side comparison of Clascoterone and Snap-8: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Clascoterone
Snap-8
Clascoterone
Clascoterone (brand name Winlevi; development codes CB-03-01 and, for the alopecia formulation, Breezula) is a first-in-class topical androgen receptor (AR) antagonist approved by the U.S. Food and Drug Administration in…
No vendor price on file.
Full Clascoterone profileSnap-8
Snap-8 (INCI: Acetyl Glutamyl Heptapeptide-1) is a synthetic octapeptide designed as an analog of the N-terminal fragment of synaptosomal-associated protein of 25 kDa (SNAP-25), which is the molecular target of botulinum…
Lowest listed price: $34.99 across 4 listings
Full Snap-8 profileSide-by-side comparison
| Attribute | Clascoterone | Snap-8 |
|---|---|---|
| Category | Pharmaceutical | Skin & Hair |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | Clascoterone's mechanism of action is competitive antagonism of androgen receptors (AR) in cutaneous target tissues — specifically the sebocytes of sebaceous glands and the dermal papilla cells of hair follicles — combined with rapid systemic hydrolysis to the… | Snap-8 (INCI Acetyl Octapeptide-3; CAS 868844-74-0) is a synthetic octapeptide, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, whose sequence mimics the N-terminal domain of SNAP-25. SNAP-25, together with Syntaxin-1 and VAMP/synaptobrevin, forms the SNARE complex… |
| Half-Life | — | Not characterized (topical peptide) |
| Typical Dose Range | — | — |
| Dosing Frequency | — | twice_daily |
| Administration | — | Topical |
| Side Effects | Clascoterone's side effect profile at the approved indication (1% cream twice daily to facial acne) is generally favorable — consistent with its design as a topical antiandrogen with rapid systemic inactivation — with most adverse events being mild application… | Topical use at cosmetic concentrations is generally well tolerated. The most commonly reported effects are mild, transient local reactions such as erythema, tightness, dryness, or stinging, usually at higher concentrations or on sensitive/periocular skin.… |
| Molecular Weight | — | 1075.16 g/mol |
| Common Vial Sizes | — | 10 |
Price History
3 data points- Ion Peptide
- OF
- Disguised Alpha
Clascoterone: potential benefits
- No structured benefit list published.
Snap-8: potential benefits
- Reduction of dynamic expression wrinkles (forehead, crow's feet, glabellar lines)
- SNARE complex interference — partial, reversible neuromuscular inhibition
- Topical alternative research model for neuromuscular relaxation without injected toxin
- Cosmetic peptide compounding research — high-purity raw powder applications
- Synergy with Argireline (Acetyl Hexapeptide-3) in SNARE-targeting formulations
Frequently asked
What's the difference between Clascoterone and Snap-8?
Clascoterone is a pharmaceutical that clascoterone's mechanism of action is competitive antagonism of androgen receptors (ar) in cutaneous target tissues — specifically the sebocytes of sebaceous glands and the dermal…. Snap-8 is a skin & hair that snap-8 (inci acetyl octapeptide-3; cas 868844-74-0) is a synthetic octapeptide, ac-glu-glu-met-gln-arg-arg-ala-asp-nh2, whose sequence mimics the n-terminal domain of snap-25.…. The two differ in mechanism, half-life (not reported vs Not characterized (topical peptide)), and typical dose range.
Which has the longer half-life, Clascoterone or Snap-8?
Clascoterone has a half-life of not reported. Snap-8 has a half-life of Not characterized (topical peptide). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Clascoterone and Snap-8?
Stacking depends on mechanism overlap, safety profile, and goals. Clascoterone and Snap-8 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.