Clascoterone vs AHK-Cu
Side-by-side comparison of Clascoterone and AHK-Cu: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Clascoterone
AHK-Cu
Clascoterone
Clascoterone (brand name Winlevi; development codes CB-03-01 and, for the alopecia formulation, Breezula) is a first-in-class topical androgen receptor (AR) antagonist approved by the U.S. Food and Drug Administration in…
No vendor price on file.
Full Clascoterone profileAHK-Cu
AHK-Cu (Ala-His-Lys-Copper) is a copper chelating tripeptide related to but distinct from GHK-Cu (Gly-His-Lys-Copper). Where GHK-Cu is the most-studied copper peptide and naturally occurs in human plasma, AHK-Cu is a…
Lowest listed price: $44.99 across 5 listings
Full AHK-Cu profileSide-by-side comparison
| Attribute | Clascoterone | AHK-Cu |
|---|---|---|
| Category | Pharmaceutical | Skin & Hair |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | Clascoterone's mechanism of action is competitive antagonism of androgen receptors (AR) in cutaneous target tissues — specifically the sebocytes of sebaceous glands and the dermal papilla cells of hair follicles — combined with rapid systemic hydrolysis to the… | AHK-Cu delivers bioavailable copper ions to follicular and dermal tissues. Copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase (antioxidant), and vascular endothelial growth factor (VEGF) signaling. The tripeptide… |
| Half-Life | — | Unknown (topical half-life, follicular retention not well characterized) |
| Typical Dose Range | — | — |
| Dosing Frequency | — | once_daily |
| Administration | — | Topical, Subcutaneous, Intradermal |
| Side Effects | Clascoterone's side effect profile at the approved indication (1% cream twice daily to facial acne) is generally favorable — consistent with its design as a topical antiandrogen with rapid systemic inactivation — with most adverse events being mild application… | — |
| Molecular Weight | — | Free peptide (AHK): 354.41 Da (C15H26N6O4). Copper complex (AHK-Cu): 415.9 Da (C15H24CuN6O4, neutral 1:1 Cu(II) complex - Cu(II) displaces two protons from the tripeptide ligand). |
| Common Vial Sizes | — | 50, 100 |
Price History
2 data points- Ion Peptide
- Disguised Alpha
Clascoterone: potential benefits
- No structured benefit list published.
AHK-Cu: potential benefits
- Hair follicle stimulation — activates anagen phase via Wnt/β-catenin in dermal papilla cells
- Reduction of follicle miniaturization in androgenetic alopecia models
- Enhanced scalp vascularity via VEGF upregulation
- Wound healing acceleration — copper cofactor for lysyl oxidase and collagen maturation
- Synergistic with GHK-Cu in multi-peptide scalp formulations
Frequently asked
What's the difference between Clascoterone and AHK-Cu?
Clascoterone is a pharmaceutical that clascoterone's mechanism of action is competitive antagonism of androgen receptors (ar) in cutaneous target tissues — specifically the sebocytes of sebaceous glands and the dermal…. AHK-Cu is a skin & hair that ahk-cu delivers bioavailable copper ions to follicular and dermal tissues. copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase…. The two differ in mechanism, half-life (not reported vs Unknown (topical half-life, follicular retention not well characterized)), and typical dose range.
Which has the longer half-life, Clascoterone or AHK-Cu?
Clascoterone has a half-life of not reported. AHK-Cu has a half-life of Unknown (topical half-life, follicular retention not well characterized). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Clascoterone and AHK-Cu?
Stacking depends on mechanism overlap, safety profile, and goals. Clascoterone and AHK-Cu should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Listings from the vendors we track. Prices change often, so check the vendor before you buy.
Before you buy Clascoterone or AHK-Cu
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. We earn an affiliate commission on some outbound clicks, and every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.