Astragalus (Huang Qi) vs SS-31
Side-by-side comparison of Astragalus (Huang Qi) and SS-31: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Astragalus (Huang Qi)
SS-31
Astragalus (Huang Qi)
Astragalus (scientific name Astragalus membranaceus, also classified as Astragalus mongholicus or Astragalus propinquus; called Huang Qi / Θ╗äΦè¬ in Mandarin Chinese — literally "yellow leader" referring to the yellow…
No vendor price on file.
Full Astragalus (Huang Qi) profileSS-31
SS-31 (elamipretide; MTP-131; formerly Bendavia; chemical sequence D-Arg-Dmt-Lys-Phe-NH2 with dimethyltyrosine at position 2) is a first-in-class aromatic-cationic tetrapeptide designed to selectively target the inner…
Lowest listed price: $72.00 across 4 listings
Full SS-31 profileSide-by-side comparison
| Attribute | Astragalus (Huang Qi) | SS-31 |
|---|---|---|
| Category | Adaptogen | Mitochondrial Peptides |
| Research Stage | Preclinical | Clinical/Approved |
| Mechanism of Action | Astragalus (Astragalus membranaceus) operates through multiple pharmacologic mechanisms reflecting its complex phytochemistry. The major active fractions — astragalus polysaccharides (APS), astragalosides (particularly astragaloside IV), cycloastragenol, and… | SS-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high concentration of cardiolipin, a signature mitochondrial anionic phospholipid - to… |
| Half-Life | — | ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding |
| Typical Dose Range | — | 20-60 mg |
| Dosing Frequency | — | Once daily subcutaneous (some protocols use 5-6 days per week) |
| Administration | — | — |
| Side Effects | Safety is generally excellent — consistent with astragalus's "superior grade" classical TCM classification and millennia of widespread medicinal and culinary use. Adverse effects at typical doses of quality preparations are uncommon and usually mild. Key… | SS-31 (elamipretide) has been generally well-tolerated across clinical trials spanning over a decade of human exposure, with adverse event profiles dominated by injection site reactions rather than systemic toxicity. This favorable safety profile reflects both… |
| Molecular Weight | — | 639.8 g/mol |
| Common Vial Sizes | — | — |
Price History
2 data points- Ion Peptide
- BHG Labs
Frequently asked
What's the difference between Astragalus (Huang Qi) and SS-31?
Astragalus (Huang Qi) is a adaptogen that astragalus (astragalus membranaceus) operates through multiple pharmacologic mechanisms reflecting its complex phytochemistry. the major active fractions — astragalus…. SS-31 is a mitochondrial peptides that ss-31's mechanism of action is distinctive among mitochondrial interventions because it exploits a fundamental physical property of the inner mitochondrial membrane - the high…. The two differ in mechanism, half-life (not reported vs ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding), and typical dose range.
Which has the longer half-life, Astragalus (Huang Qi) or SS-31?
Astragalus (Huang Qi) has a half-life of not reported. SS-31 has a half-life of ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Astragalus (Huang Qi) and SS-31?
Stacking depends on mechanism overlap, safety profile, and goals. Astragalus (Huang Qi) and SS-31 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.