AHK-Cu vs RU-58841
Side-by-side comparison of AHK-Cu and RU-58841: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
AHK-Cu
RU-58841
AHK-Cu
AHK-Cu (Ala-His-Lys-Copper) is a copper chelating tripeptide related to but distinct from GHK-Cu (Gly-His-Lys-Copper). Where GHK-Cu is the most-studied copper peptide and naturally occurs in human plasma, AHK-Cu is a…
Lowest listed price: $44.99 across 5 listings
Full AHK-Cu profileRU-58841
RU-58841 (also known as PSK-3841 or HMR-3841, and commonly written simply as RU in hair-loss forums) is a non-steroidal androgen receptor antagonist originally developed by Roussel Uclaf (later absorbed into Sanofi) in…
Lowest listed price: $49.99 across 2 listings
Full RU-58841 profileSide-by-side comparison
| Attribute | AHK-Cu | RU-58841 |
|---|---|---|
| Category | Skin & Hair | Other |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | AHK-Cu delivers bioavailable copper ions to follicular and dermal tissues. Copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase (antioxidant), and vascular endothelial growth factor (VEGF) signaling. The tripeptide… | RU-58841 is a non-steroidal androgen receptor (AR) antagonist with a chemical structure unrelated to testosterone, DHT, or the steroidal antiandrogens (cyproterone acetate, spironolactone). Its pharmacology was characterized in the early 1990s by teams at… |
| Half-Life | Unknown (topical half-life, follicular retention not well characterized) | — |
| Typical Dose Range | — | 25 mg - 50 mg topical daily (dissolved in vehicle) |
| Dosing Frequency | once_daily | — |
| Administration | Topical, Subcutaneous, Intradermal | — |
| Side Effects | — | The side-effect profile of RU-58841 is not formally characterized in humans. What follows is a synthesis of the preclinical literature, the limited phase I human data, user-reported outcomes from hair-loss forums, and mechanistic inference from the broader… |
| Molecular Weight | Free peptide (AHK): 354.41 Da (C15H26N6O4). Copper complex (AHK-Cu): 415.9 Da (C15H24CuN6O4, neutral 1:1 Cu(II) complex - Cu(II) displaces two protons from the tripeptide ligand). | 489.41 g/mol |
| Common Vial Sizes | 50, 100 | — |
Price History
2 data points- Ion Peptide
- Disguised Alpha
Price History
2 data points- Half Nattys
- Disguised Alpha
AHK-Cu: potential benefits
- Hair follicle stimulation — activates anagen phase via Wnt/β-catenin in dermal papilla cells
- Reduction of follicle miniaturization in androgenetic alopecia models
- Enhanced scalp vascularity via VEGF upregulation
- Wound healing acceleration — copper cofactor for lysyl oxidase and collagen maturation
- Synergistic with GHK-Cu in multi-peptide scalp formulations
RU-58841: potential benefits
- Prevention of hair follicle miniaturization
- Hair loss reduction (androgenic alopecia)
- Topical application minimizes systemic effects
- Alternative to finasteride without systemic 5-AR inhibition
Frequently asked
What's the difference between AHK-Cu and RU-58841?
AHK-Cu is a skin & hair that ahk-cu delivers bioavailable copper ions to follicular and dermal tissues. copper acts as a cofactor for lysyl oxidase (collagen/elastin crosslinking), superoxide dismutase…. RU-58841 is a other that ru-58841 is a non-steroidal androgen receptor (ar) antagonist with a chemical structure unrelated to testosterone, dht, or the steroidal antiandrogens (cyproterone acetate,…. The two differ in mechanism, half-life (Unknown (topical half-life, follicular retention not well characterized) vs not reported), and typical dose range.
Which has the longer half-life, AHK-Cu or RU-58841?
AHK-Cu has a half-life of Unknown (topical half-life, follicular retention not well characterized). RU-58841 has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, AHK-Cu or RU-58841?
Lowest listed price on BodyHackGuide: AHK-Cu from $44.99, RU-58841 from $49.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack AHK-Cu and RU-58841?
Stacking depends on mechanism overlap, safety profile, and goals. AHK-Cu and RU-58841 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Listings from the vendors we track. Prices change often, so check the vendor before you buy.
Before you buy AHK-Cu or RU-58841
Check the vendor trust score. Every supplier we track is rated 0-100 on COA verification, payment transparency, shipping, reviews, and listings: one published, reproducible methodology, applied to every vendor.
Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.