Also known as: Mod GRF 1-29, CJC-1295 without DAC, Modified GRF 1-29, CJC No-DAC
CJC-1295 No-DAC (also known as Mod GRF 1-29) is a 29-amino-acid synthetic peptide modeled on the active N-terminal fragment of human Growth Hormone Releasing Hormone (GHRH 1-29). Four amino acid substitutions stabilize the peptide against enzymatic degradation but, unlike CJC-1295 with DAC, this version does NOT carry the Drug Affinity Complex (DAC) - meaning it has a short serum half-life (~30 minutes) and produces a single physiological GH pulse rather than sustained GHRH stimulation. The short pulse profile is closer to natural pulsatile GHRH biology, which makes Mod GRF 1-29 the preferred choice when researchers want to amplify natural GH peaks (e.g., paired with ipamorelin pre-bed) without continuous GHRH receptor stimulation..
Overview
At A Glance
Binds the GHRH receptor on anterior pituitary somatotrophs, triggering Gs-coupled cAMP signaling and pulsatile growth hormone release. Without DAC, the peptide clears within ~30 minutes, producing a single GH pulse and returning the GHRH receptor to baseline sensitivity. This con…
Overview
CJC-1295 No-DAC (also known as Mod GRF 1-29) is a 29-amino-acid synthetic peptide modeled on the active N-terminal fragment of human Growth Hormone Releasing Hormone (GHRH 1-29). Four amino acid substitutions stabilize the peptide against enzymatic degradation but, unlike CJC-1295 with DAC, this version does NOT carry the Drug Affinity Complex (DAC) - meaning it has a short serum half-life (~30 minutes) and produces a single physiological GH pulse rather than sustained GHRH stimulation. The short pulse profile is closer to natural pulsatile GHRH biology, which makes Mod GRF 1-29 the preferred choice when researchers want to amplify natural GH peaks (e.g., paired with ipamorelin pre-bed) without continuous GHRH receptor stimulation.
Potential Research Fields
Chemical Information
IUPAC Name
Not yet available
CAS Number
Not yet available
Molecular Formula
Not yet available
Molecular Mass
3367.9 Da (average)
Amino Acid Sequence
Dosing & Protocols
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Research
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Interactions
Contraindications
Active malignancy. Pregnancy and breastfeeding. Active diabetic retinopathy. Active acromegaly or pituitary adenoma. Caution in T2D - GH antagonizes insulin action.
Research Disclaimer
This interaction data is compiled from published research and community reports. It may not be exhaustive. Always consult a healthcare professional before combining compounds.
$79.99
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1
1
vial
Tracking since Sep 5, 2026 · 1 data point
Vendors Selling CJC-1295 No-DAC (Mod GRF 1-29)
How we score these vendors
Every supplier above is graded 0 to 100 on COA verification, payment transparency, shipping, reviews, and active listings. Methodology published, no pay-to-rank.
Research Score
0 PubMed results
Quality Indicators
Data Completeness
63%COA Verification
0
Verified COAs
1
Vendors w/ COA
Latest test: 9/16/2026
Quick Facts
Half-Life
~30 minutes (no DAC means no extended binding)
Molecular Weight
3367.9 Da (average)
Administration
Subcutaneous
Trial Phase
Preclinical / Research peptide
Safety Profile
Common Side Effects
- • Injection site irritation
- • Transient flushing post-injection
- • Mild headache during first 1-2 weeks
- • Mild water retention with long use
Research Disclaimer
This information is for educational and research purposes only. Not intended as medical advice. Consult a healthcare professional before use.
Frequently Asked Questions
What is CJC-1295 No-DAC (Mod GRF 1-29) used for in research?
CJC-1295 No-DAC (also known as Mod GRF 1-29) is a 29-amino-acid synthetic peptide modeled on the active N-terminal fragment of human Growth Hormone Releasing Hormone (GHRH 1-29). Four amino acid substitutions stabilize the peptide against enzymatic degradation but, unlike CJC-1295 with DAC, this version does NOT carry the Drug Affinity Complex (DAC) - meaning it has a short serum half-life (~30 minutes) and produces a single physiological GH pulse rather than sustained GHRH stimulation.
The short pulse profile is closer to natural pulsatile GHRH biology, which makes Mod GRF 1-29 the preferred choice when researchers want to amplify natural GH peaks (e.g., paired with ipamorelin pre-bed) without continuous GHRH receptor stimulation.
What forms does CJC-1295 No-DAC (Mod GRF 1-29) come in?
CJC-1295 No-DAC (Mod GRF 1-29) is available in vial form.
How do I compare CJC-1295 No-DAC (Mod GRF 1-29) vendors?
Compare prices, payment methods, shipping, and COA scores across 1 vendor.
How many vendors sell CJC-1295 No-DAC (Mod GRF 1-29), and what does it cost per mg?
1 of the vendors BodyHackGuide tracks list CJC-1295 No-DAC (Mod GRF 1-29) (1 listing). The lowest listed price BodyHackGuide has recorded for CJC-1295 No-DAC (Mod GRF 1-29) is $79.99. No CJC-1295 No-DAC (Mod GRF 1-29) listing recorded as in stock carries a milligram count, so BodyHackGuide states no price per milligram for CJC-1295 No-DAC (Mod GRF 1-29).
Which vendors have third-party COAs for CJC-1295 No-DAC (Mod GRF 1-29) on file at BodyHackGuide?
BodyHackGuide holds 65 third-party certificate records for CJC-1295 No-DAC (Mod GRF 1-29), from Half Nattys. No editor has read any of BodyHackGuide's 65 certificate records for CJC-1295 No-DAC (Mod GRF 1-29). The laboratory named on BodyHackGuide's CJC-1295 No-DAC (Mod GRF 1-29) certificate records is Freedom Diagnostics Testing, and the newest test date on them is 17 September 2026. Each vendor page on BodyHackGuide shows how many certificate records BodyHackGuide holds for that vendor and links to each record that has its own page.
Research Tools
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