Tesofensine vs SLU-PP-332
Side-by-side comparison of Tesofensine and SLU-PP-332: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Tesofensine
SLU-PP-332
Tesofensine
Tesofensine (NS2330) is an orally-administered small-molecule triple monoamine reuptake inhibitor — it blocks the reuptake of noradrenaline, dopamine, and serotonin, placing it in the same broad pharmacologic class as…
Lowest listed price: $79.99 across 2 listings
Full Tesofensine profileSLU-PP-332
SLU-PP-332 is the first-generation synthetic pan-agonist of the estrogen-related receptors (ERRα, ERRβ, ERRγ) developed by the laboratory of Thomas Burris at Saint Louis University and reported in a landmark 2023…
Lowest listed price: $69.99 across 5 listings
Full SLU-PP-332 profileSide-by-side comparison
| Attribute | Tesofensine | SLU-PP-332 |
|---|---|---|
| Category | Weight Loss | Performance |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | Tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. By inhibiting the neurotransmitter transporters (NET, DAT, and SERT respectively), tesofensine raises synaptic… | SLU-PP-332 acts through pan-agonism of the three estrogen-related receptors (ERRα/NR3B1, ERRβ/NR3B2, ERRγ/NR3B3), a subfamily of orphan nuclear receptors that regulate oxidative metabolism, mitochondrial biogenesis, and exercise-responsive gene expression. The… |
| Half-Life | — | — |
| Typical Dose Range | 0.25 mg - 1 mg daily (oral) | Research compound — no established human doses. Animal studies: 10-50 mg/kg |
| Dosing Frequency | — | — |
| Administration | — | — |
| Side Effects | Tesofensine's side effect profile reflects its monoamine-enhancing mechanism. Most effects are predictable extensions of NE, DA, and 5-HT elevation. The cardiovascular profile is the dominant clinical concern and the primary reason regulators have not approved… | The side effect profile of SLU-PP-332 in humans is undocumented because no clinical trials have been conducted. Rodent studies report generally acceptable tolerability at doses producing exercise-mimetic metabolic effects, without overt signs of toxicity on… |
| Molecular Weight | 298.24 g/mol | 535.54 g/mol |
| Common Vial Sizes | — | — |
Price tracking
Price History
3 data points- Half Nattys
- Ion Peptide
- BHG Labs
Tesofensine: potential benefits
- Significant weight loss (10-15% body weight)
- Appetite suppression
- Increased metabolic rate
- Enhanced dopamine-driven motivation
SLU-PP-332: potential benefits
- Exercise mimicry without physical exertion
- Enhanced fat oxidation
- Increased mitochondrial biogenesis
- Improved endurance capacity
- Muscle fiber type conversion
- Metabolic health improvement
Frequently asked
What's the difference between Tesofensine and SLU-PP-332?
Tesofensine is a weight loss that tesofensine blocks the presynaptic reuptake of three monoamine neurotransmitters: noradrenaline (norepinephrine), dopamine, and serotonin. by inhibiting the neurotransmitter…. SLU-PP-332 is a performance that slu-pp-332 acts through pan-agonism of the three estrogen-related receptors (errα/nr3b1, errβ/nr3b2, errγ/nr3b3), a subfamily of orphan nuclear receptors that regulate oxidative…. The two differ in mechanism, half-life (not reported vs not reported), and typical dose range.
Which has the longer half-life, Tesofensine or SLU-PP-332?
Tesofensine has a half-life of not reported. SLU-PP-332 has a half-life of not reported. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, Tesofensine or SLU-PP-332?
Lowest listed price on BodyHackGuide: Tesofensine from $79.99, SLU-PP-332 from $69.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack Tesofensine and SLU-PP-332?
Stacking depends on mechanism overlap, safety profile, and goals. Tesofensine and SLU-PP-332 should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
See current vendor prices
Listings from the vendors we track. Prices change often, so check the vendor before you buy.
Before you buy Tesofensine or SLU-PP-332
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.