Livagen vs Humanin
Side-by-side comparison of Livagen and Humanin: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Livagen
Humanin
Livagen
Livagen is a short synthetic peptide developed in Russia by Vladimir Khavinson and his collaborators at the St. Petersburg Institute of Bioregulation and Gerontology, positioned as a "liver bioregulator" intended to…
No vendor price on file.
Full Livagen profileHumanin
Humanin is a 24-amino-acid peptide (MAPRGFSCLLLLTSEIDLPVKRRA) encoded within the mitochondrial 16S ribosomal RNA gene and translated from a short open reading frame that was not recognized as biologically active until…
Lowest listed price: $85.60 across 2 listings
Full Humanin profileSide-by-side comparison
| Attribute | Livagen | Humanin |
|---|---|---|
| Category | Recovery | Recovery |
| Research Stage | Preclinical | Preclinical |
| Mechanism of Action | Mechanism of Action Livagen's proposed mechanism is the standard Khavinson short-peptide bioregulator model applied to hepatic tissue. The framework, developed at the St. Petersburg Institute of Bioregulation and Gerontology across roughly 35 years, proposes… | Humanin signals through a heterotrimeric cell-surface receptor complex consisting of ciliary neurotrophic factor receptor alpha (CNTFR-alpha), WSX-1 (also known as IL-27R-alpha), and glycoprotein 130 (gp130) ([Ying et al., 2004]; [Hashimoto et al., 2009]).… |
| Half-Life | — | Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist. |
| Typical Dose Range | 20 mg oral/sublingual capsule once daily for 10 consecutive days per cycle (or 2-5 mg subcutaneous daily using synthetic peptide); 60-90 day washout between cycles | Research compound — no established human doses |
| Dosing Frequency | — | Once daily subcutaneous in anecdotal use (some split twice daily for the short half-life); no validated human regimen |
| Administration | — | — |
| Side Effects | Side Effects and Safety Livagen has been administered to humans and rodents in Russian studies for roughly 25 years with a reassuringly sparse side-effect literature — but that literature is also extremely small, unblinded, and biased toward reporting positive… | The side effect profile of humanin in humans is not established because no properly designed clinical trials have been published. The preclinical safety profile in rodents is reassuring: across numerous studies using wild-type humanin and HNG at doses… |
| Molecular Weight | ~461.5 Da (C18H31N5O9) | 2687.26 Da |
| Common Vial Sizes | — | — |
Price History
2 data points- Disguised Alpha
- LB
Livagen: potential benefits
- Liver tissue repair and regeneration
- Enhanced detoxification capacity
- Hepatocyte function normalization
- Liver anti-aging support
Humanin: potential benefits
- Cytoprotective effects
- Anti-apoptotic properties
- Neuroprotective potential
- Cardioprotective effects
- Cellular stress resistance
Frequently asked
What's the difference between Livagen and Humanin?
Livagen is a recovery that mechanism of action livagen's proposed mechanism is the standard khavinson short-peptide bioregulator model applied to hepatic tissue. the framework, developed at the st.…. Humanin is a recovery that humanin signals through a heterotrimeric cell-surface receptor complex consisting of ciliary neurotrophic factor receptor alpha (cntfr-alpha), wsx-1 (also known as il-27r-alpha),…. The two differ in mechanism, half-life (not reported vs Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist.), and typical dose range.
Which has the longer half-life, Livagen or Humanin?
Livagen has a half-life of not reported. Humanin has a half-life of Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist.. Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Can you stack Livagen and Humanin?
Stacking depends on mechanism overlap, safety profile, and goals. Livagen and Humanin should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Related comparisons
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