Cagrilintide vs 5-Amino-1MQ
Side-by-side comparison of Cagrilintide and 5-Amino-1MQ: mechanism, half-life, dose range, safety profile, and vendor pricing.
Price snapshot
Cagrilintide
5-Amino-1MQ
Cagrilintide
Cagrilintide (also known as AM833, development code NN9838) is a long-acting amylin analog developed by Novo Nordisk as a next-generation weight-management therapy, designed to be co-administered with the GLP-1 receptor…
Lowest listed price: $49.99 across 3 listings
Full Cagrilintide profile5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to…
Lowest listed price: $29.99 across 14 listings
Full 5-Amino-1MQ profileSide-by-side comparison
| Attribute | Cagrilintide | 5-Amino-1MQ |
|---|---|---|
| Category | Metabolic & Weight Loss | Weight Loss |
| Research Stage | Phase 3 | Preclinical |
| Mechanism of Action | Cagrilintide engages both amylin and calcitonin receptor signaling with careful receptor selectivity profiling. Native amylin binds primarily to amylin receptors - heterodimeric complexes of the calcitonin receptor (CTR) with one of three receptor… | 5-Amino-1MQ works by inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to the nitrogen of nicotinamide (vitamin B3 amide), producing 1-methylnicotinamide (1-MNA) and… |
| Half-Life | ~159 hours (approximately 7 days) | ~6–12 hours (oral) |
| Typical Dose Range | — | 50 mg - 150 mg daily (oral or injection) |
| Dosing Frequency | Once weekly | Once daily oral |
| Administration | — | Oral |
| Side Effects | Cagrilintide's side-effect profile is dominated by gastrointestinal effects similar to but distinct from GLP-1 agonists, with some amylin-specific considerations. Most Common Side Effects (from trials): Gastrointestinal (dose-dependent): - Nausea: in the Phase… | The side effect profile of 5-amino-1MQ in humans is not documented because there are no human clinical trials. Rodent studies report generally good tolerability at doses producing metabolic and muscle benefits, without obvious signs of hepatotoxicity,… |
| Molecular Weight | 4409 g/mol | 159.21 g/mol |
| Common Vial Sizes | — | 50mg capsules, 100mg capsules |
Price History
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Cagrilintide: potential benefits
- Weight loss
- Appetite suppression (via different pathway than GLP-1)
- Glucagon suppression
- Complementary to GLP-1 agonists
5-Amino-1MQ: potential benefits
- Enhanced fat metabolism and weight loss
- Increased NAD+ levels in adipose tissue
- Improved cellular energy production
- Anti-aging properties via sirtuin activation
Frequently asked
What's the difference between Cagrilintide and 5-Amino-1MQ?
Cagrilintide is a metabolic & weight loss that cagrilintide engages both amylin and calcitonin receptor signaling with careful receptor selectivity profiling. native amylin binds primarily to amylin receptors - heterodimeric…. 5-Amino-1MQ is a weight loss that 5-amino-1mq works by inhibiting nicotinamide n-methyltransferase (nnmt), an enzyme that catalyzes the transfer of a methyl group from s-adenosyl-l-methionine (sam) to the nitrogen…. The two differ in mechanism, half-life (~159 hours (approximately 7 days) vs ~6–12 hours (oral)), and typical dose range.
Which has the longer half-life, Cagrilintide or 5-Amino-1MQ?
Cagrilintide has a half-life of ~159 hours (approximately 7 days). 5-Amino-1MQ has a half-life of ~6–12 hours (oral). Longer half-lives generally mean less frequent dosing but slower on/off kinetics.
Which is cheaper, Cagrilintide or 5-Amino-1MQ?
Lowest listed price on BodyHackGuide: Cagrilintide from $49.99, 5-Amino-1MQ from $29.99. Prices are pulled from the vendor listings tracked on BHG and change frequently. See the compare tables on each compound page for the current set of offers.
Can you stack Cagrilintide and 5-Amino-1MQ?
Stacking depends on mechanism overlap, safety profile, and goals. Cagrilintide and 5-Amino-1MQ should only be stacked after reviewing each compound's individual protocol page, side effect profile, and any published interaction data. Use the BodyHackGuide stack builder for a structured review before combining research compounds.
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Related comparisons
Research use only. BodyHackGuide is a research and price-comparison reference. The compounds discussed on this page are not approved by the FDA for human consumption and are sold strictly for laboratory research. Prices shown are pulled from vendor listings tracked on BHG and are subject to change. Every vendor is ranked on the same public, reproducible methodology. See editorial standards and affiliate disclosure.