--- title: "Research Compound Wiki: 273 Peptide & Nootropic Profiles" url: https://www.bodyhackguide.co/wiki description: "Evidence-based profiles for 273 research compounds: PubMed data, dosing ranges, half-lives, mechanisms, and vendor pricing." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Research Database # Research Compound Wiki Evidence-based profiles for **273** research compounds (peptides, nootropics, SARMs, and growth-hormone secretagogues) with PubMed citations, mechanisms of action, dosing ranges, half-lives, and vendor pricing. 273 Compounds 154,770 PubMed Results 65 Categories The BodyHackGuide wiki indexes research compounds across 65 major categories. Profiles show PubMed study counts, dosing data from published protocols, and prices from the vendors we track. Compounds are tagged by research stage (preclinical, Phase I-III, approved) and research field (longevity, metabolic, cognitive, recovery, etc.). Nothing here is medical advice. Everything is for research purposes only. ## Editor's Picks Compounds with the strongest clinical data, widest research coverage, or highest reader interest. ### Semaglutide Metabolic & Weight Loss FDA Approved Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) with a molecular weight of 4113.58 Da and CAS number 910463-68-2. It is a 31-amino-acid peptide analog of human GLP-1(7-37) with two key structural modifications: an alpha-aminoisobutyric acid (Aib) substitution at position 8 that confers resistance to dipeptidyl peptidase-4 (DPP-4) enzymatic degradation, and a C18 fatty diacid chain attached via a linker at position 26 (lysine) that enables non-covalent binding to serum albumin. ~7 days (168 hours), enabled by C18 fatty diacid albumin-binding modification Diabetes (Ozempic): 250-1000 mcg weekly; Weight management (Wegovy): 2400 mcg weekly (after 16-week titration); Oral (Rybelsus): 3-14 mg daily Subcutaneous (weekly) Oral (daily) 3273 studies View Profile https://www.bodyhackguide.co/compound/semaglutide ### TB-500 Injury, Repair & Recovery Phase 2 TB-500 is the name the market and the FDA use for a short synthetic fragment of thymosin beta-4: the seven-amino-acid, N-acetylated actin-binding sequence Ac-LKKTETQ (residues 17 to 23). Thymosin beta-4 itself is a 43-amino-acid peptide (about 4963 Da acetylated) and one of the most abundant intracellular actin-sequestering molecules in mammalian cells. Plasma half-life is short - full-length thymosin beta-4 clears on the order of hours, while the short LKKTETQ actin-binding fragment clears within minutes. Tissue-level regenerative effects persist substantially longer than plasma exposure. 2000-5000 mcg (2-5 mg) subcutaneous 2x weekly loading; 2000 mcg (2 mg) weekly maintenance Subcutaneous Intramuscular 1039 studies View Profile https://www.bodyhackguide.co/compound/tb-500 ### Tirzepatide Metabolic & Weight Loss FDA Approved Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist with a molecular weight of 4813.45 Da and CAS number 2023788-19-2. It is a 39-amino-acid synthetic peptide based on the native GIP sequence with modifications that confer activity at both GIP and GLP-1 receptors. ~5 days (approximately 120 hours), enabled by C20 fatty diacid albumin-binding modification 2500 mcg (2.5 mg) starting dose, titrated every 4 weeks through 5000, 7500, 10000, 12500, to 15000 mcg (15 mg) maximum weekly dose Subcutaneous (weekly) 626 studies View Profile https://www.bodyhackguide.co/compound/tirzepatide ### BPC-157 Injury, Repair & Recovery Preclinical BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a partial sequence of human gastric juice protein BPC. It has a molecular weight of 1419.53 Da and a CAS number of 137525-51-0. Short plasma half-life. The first formal preclinical ADME study reported an elimination half-life under ~30 minutes after IV/IM dosing in rats and dogs, with linear dose-proportional kinetics (PMID: 36588717); a 2026 biopharmaceutical review confirms this sub-30-minute plasma half-life and highlights a pharmacokinetic-pharmacodynamic disconnect, as biological effects persist for hours to days (PMID: 42198317). No full human pharmacokinetic study has been published; twice-daily dosing is empirical/community-standard rather than PK-derived. 200-500 mcg subcutaneous 1-2x daily (community protocols); 1-10 mcg/kg in animal studies Subcutaneous Oral 214 studies View Profile https://www.bodyhackguide.co/compound/bpc-157 ### Retatrutide Metabolic & Weight Loss Phase 3 Retatrutide (also coded LY3437943) is an investigational once-weekly triple-agonist at the GLP-1, GIP, and glucagon receptors. It is the third-generation incretin-based therapy developed by Eli Lilly. ~6 days (plasma, albumin-bound) 1,000–12,000 mcg (1–12 mg) per week subcutaneous 135 studies View Profile https://www.bodyhackguide.co/compound/retatrutide ### CJC-1295 (Mod GRF 1-29) Growth Hormone / IGF-1 Axis Preclinical CJC-1295 without DAC (also called Modified GRF 1-29 or MOD-GRF 1-29) is a 30-amino-acid analog of the first 29 residues of endogenous Growth Hormone Releasing Hormone (GHRH), with four strategic substitutions (D-Ala² for DPP-4 resistance, Gln⁸, Ala¹⁵, Leu²⁷) that extend its plasma half-life from <2 minutes (native GHRH) to ~30 minutes. It was developed by ConjuChem Biotechnologies as the non-albumin-binding companion to CJC-1295 with DAC. This is the physiologic version of CJC-1295. ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding) Without DAC: 100-300 mcg subcutaneous 1-3x daily (typically pre-bedtime); With DAC: 1000-2000 mcg subcutaneous once weekly Subcutaneous 29 studies View Profile https://www.bodyhackguide.co/compound/cjc-1295 ## Most-Studied Compounds Ranked by PubMed citation count: the compounds with the deepest peer-reviewed literature base. 1. 01 Probiotics Supplement 24,468 PubMed results https://www.bodyhackguide.co/compound/probiotics 2. 02 Melatonin Sleep & Circadian 12,556 PubMed results https://www.bodyhackguide.co/compound/melatonin 3. 03 Panax ginseng Adaptogen 6,421 PubMed results https://www.bodyhackguide.co/compound/panax-ginseng 4. 04 Vitamin E Vitamin 6,280 PubMed results https://www.bodyhackguide.co/compound/vitamin-e 5. 05 Silymarin Hepatoprotective Flavonolignan 5,824 PubMed results https://www.bodyhackguide.co/compound/silymarin 6. 06 Beta-Sitosterol Herbal 5,651 PubMed results https://www.bodyhackguide.co/compound/beta-sitosterol 7. 07 Vitamin A Vitamin 5,362 PubMed results https://www.bodyhackguide.co/compound/vitamin-a 8. 08 DHEA Hormone 4,979 PubMed results https://www.bodyhackguide.co/compound/dhea 9. 09 Astaxanthin Carotenoid 4,720 PubMed results https://www.bodyhackguide.co/compound/astaxanthin 10. 10 Caffeine Nootropic 4,235 PubMed results https://www.bodyhackguide.co/compound/caffeine Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) ## Adaptogen (17) Research compounds in the Adaptogen family, compiled from peer-reviewed literature and clinical trial registries. ### Panax ginseng Adaptogen Preclinical Panax ginseng is the canonical Asian adaptogen, the compound that gave "ginseng" its name in the global supplement lexicon, and the most extensively studied herbal medicine in the Asian pharmacopeia. 6,421 PubMed View Profile https://www.bodyhackguide.co/compound/panax-ginseng ### Dong Quai Adaptogen Preclinical Dong Quai (scientific name Angelica sinensis (Oliv.) Diels; also spelled Dang Gui, Tang Kuei, or Dong Kwai; Chinese σ╜ôσ╜Æ / τò╢µ¡╕) is a perennial herb of the family Apiaceae (the carrot, parsley, and celery family — notable for containing many fragrant, volatile-oil-rich medicinal plants) native to the cool, high-altitude regions of central and northwestern China, particularly Gansu Province (the Min County region is traditionally considered the premium cultivation area), Yunnan, Sichuan, Shaanxi, and Hubei provinces. 1,308 PubMed View Profile https://www.bodyhackguide.co/compound/dong-quai ### Fadogia Agrestis Adaptogen Preclinical Fadogia agrestis (also sometimes called "Black Aphrodisiac" or "West African Aphrodisiac" in English-language supplement marketing; bakin gagai in Hausa; and historically known by various regional names across its native range) is a flowering shrub of the family Rubiaceae (the coffee and cinchona family) native to the savanna regions of tropical West and Central Africa — with documented distribution across Nigeria, Sudan, Cameroon, Chad, Senegal, Burkina Faso, and surrounding countries. 1,140 PubMed View Profile https://www.bodyhackguide.co/compound/fadogia-agrestis ### Reishi Adaptogen Preclinical Reishi (scientific name Ganoderma lucidum, though the species most commonly cultivated and studied in East Asia is now properly recognized as Ganoderma lingzhi following a 2012 taxonomic revision) is a polypore mushroom known in Chinese as lingzhi (Θ¥êΦè¥, "spirit plant" or "mushroom of immortality"), in Japanese as reishi (Θ£èΦè¥) or mannentake ("10,000-year mushroom"), in Korean as yeongji (∞ÿü∞ºÇ), and in Vietnamese as linh chi. 951 PubMed View Profile https://www.bodyhackguide.co/compound/reishi ### Ashwagandha Adaptogen Preclinical Ashwagandha (Withania somnifera, also called "Indian ginseng" and "winter cherry") is the most studied and most clinically validated herbal adaptogen in the contemporary supplement market. 890 PubMed View Profile https://www.bodyhackguide.co/compound/ashwagandha ### Schisandra Adaptogen Preclinical Schisandra (scientific name Schisandra chinensis; called wu wei zi in Chinese, literally "five-flavor fruit" — referring to the berry's unique property of exhibiting all five basic tastes simultaneously: sweet, sour, salty, bitter, and pungent/spicy — omija in Korean, and gomishi in Japanese) is a deciduous woody vine native to the cold temperate forests of Northeast China, Korea, eastern Russia (particularly the Russian Far East, Primorsky region, and parts of Siberia), and Japan, producing distinctive bright-red berries in dense clusters during late summer and autumn. 794 PubMed View Profile https://www.bodyhackguide.co/compound/schisandra ## Anabolic Peptide (2) Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide. ### IGF-1 Des(1-3) Anabolic Peptide Preclinical / Research peptide IGF-1 Des(1-3) is a truncated variant of insulin-like growth factor-1 missing the first three N-terminal amino acids (Gly-Pro-Glu). t½ ~20-30 minutes serum 20-100 mcg 32 PubMed View Profile https://www.bodyhackguide.co/compound/igf-1-des ### MGF (Mechano Growth Factor) MGF (Mechano Growth Factor) is the local IGF-1Ec splice variant of insulin-like growth factor-1, expressed in skeletal muscle in response to mechanical loading. t½ Reported/estimated only; no published human PK data. Commonly cited community figures are ~5-7 minutes for native MGF and ~24-48 hours for PEGylated PEG-MGF; neither has been established in human pharmacokinetic studies. 100-300 mcg (PEG-MGF) 20 PubMed View Profile https://www.bodyhackguide.co/compound/mgf ## Antioxidants (2) Research compounds in the Antioxidants family, compiled from peer-reviewed literature and clinical trial registries. ### Curcumin Antioxidants Preclinical Curcumin is the principal bioactive polyphenol extracted from the rhizome of Curcuma longa (turmeric), constituting approximately 2-8% of dried turmeric root by weight along with two related curcuminoids (demethoxycurcumin and bisdemethoxycurcumin). 2 PubMed View Profile https://www.bodyhackguide.co/compound/curcumin ### NAC Antioxidants Preclinical N-acetylcysteine (NAC) is the acetylated form of the amino acid L-cysteine — a small thiol-containing molecule that serves as a rate-limiting precursor for glutathione (GSH) synthesis and, independently, as a direct antioxidant and mucolytic agent. Preclinical View Profile https://www.bodyhackguide.co/compound/nac ## Bioregulator Peptide (2) ### Epitalon Bioregulator Peptide Preclinical Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Vladimir Khavinson at the St. t½ ~30-60 minutes (peptide; biological effects extend long beyond plasma clearance) 47 PubMed View Profile https://www.bodyhackguide.co/compound/epitalon ### Pineleon Bioregulator Peptide Preclinical Pineleon is a multi-peptide bioregulator blend combining motifs from the Khavinson-school short peptides — typically Pinealon (Glu-Asp-Arg, a pineal-gland-derived tripeptide) along with epigenetic-tier short peptides like Epitalon and Cortexin-derived sequences. t½ ~variable (constituent peptides range 30 min to several hours) 2 PubMed View Profile https://www.bodyhackguide.co/compound/pineleon ## Carotenoid (5) Research compounds in the Carotenoid family, compiled from peer-reviewed literature and clinical trial registries. ### Astaxanthin Carotenoid Preclinical Astaxanthin is a red-orange keto-carotenoid xanthophyll, chemically classified as a 3,3''-dihydroxy-beta,beta-carotene-4,4''-dione. 4,720 PubMed View Profile https://www.bodyhackguide.co/compound/astaxanthin ### Lutein Carotenoid Preclinical Lutein is a dihydroxy-xanthophyll carotenoid that functions as the primary blue-light-absorbing, antioxidant macular pigment of the human retina, where along with its stereoisomers zeaxanthin and meso-zeaxanthin it concentrates selectively in the central macula at concentrations exceeding 1,000 times those found in any other body tissue. 2,075 PubMed View Profile https://www.bodyhackguide.co/compound/lutein ### Beta-carotene Carotenoid Preclinical Beta-carotene is the most prominent provitamin A carotenoid and one of the most-studied dietary pigments in human nutrition. Preclinical View Profile https://www.bodyhackguide.co/compound/beta-carotene ### Lycopene Carotenoid Preclinical Lycopene is a red pigment carotenoid belonging to the acyclic hydrocarbon carotene subfamily, chemically designated psi,psi-carotene. Preclinical View Profile https://www.bodyhackguide.co/compound/lycopene ### Zeaxanthin Carotenoid Preclinical Zeaxanthin is a xanthophyll carotenoid that functions alongside lutein and meso-zeaxanthin as one of the three pigments comprising the macula lutea — the yellow spot in the central retina responsible for high-acuity daytime vision. Preclinical View Profile https://www.bodyhackguide.co/compound/zeaxanthin ## Cofactor (1) Research compounds in the Cofactor family, compiled from peer-reviewed literature and clinical trial registries. ### PQQ (Pyrroloquinoline Quinone) Cofactor Preclinical Pyrroloquinoline quinone (PQQ, methoxatin) is a small tricyclic o-quinone originally discovered in 1964 as the prosthetic group of bacterial methanol dehydrogenase. 1,520 PubMed View Profile https://www.bodyhackguide.co/compound/pqq ## Cognition, Mood & Neuroprotection (1) Research compounds in the Cognition, Mood & Neuroprotection family, compiled from peer-reviewed literature and clinical trial registries. ### DSIP (Delta Sleep-Inducing Peptide) Cognition, Mood & Neuroprotection Preclinical Delta sleep-inducing peptide (DSIP) is a nonapeptide — a 9-amino-acid neuropeptide with sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE, 848 Da molecular weight) — first isolated in 1977 from the cerebral venous blood of rabbits subjected to electrical stimulation of the intralaminar thalamus, a brain region involved in sleep regulation. t½ ~7-15 minutes (IV; plasma clearance is rapid, though subjective sleep effects can outlast measurable blood levels) 100–300 mcg per injection 518 PubMed View Profile https://www.bodyhackguide.co/compound/dsip ## Cognitive (3) Research compounds in the Cognitive family, compiled from peer-reviewed literature and clinical trial registries. ### N-Acetyl-Selank Cognitive Preclinical (the N-acetyl analog has no dedicated studies); parent Selank has limited clinical use in Russia N-Acetyl-Selank is the N-terminally acetylated analog of Selank, a tuftsin-derived heptapeptide used intranasally for its reported anxiolytic and nootropic effects. t½ Not established for the N-acetyl analog. Parent Selank has a very short plasma half-life (on the order of minutes, as expected for a small peptide) but produces behavioral effects lasting hours, attributed to active fragments and downstream enkephalin/GABA modulation. N-acetylation is claimed to slow N-terminal degradation and extend duration, but this is unquantified in published literature. 100-900 mcg Preclinical View Profile https://www.bodyhackguide.co/compound/n-acetyl-selank ### N-Acetyl-Semax Cognitive Duplicate entry - see NA-Semax This is a duplicate/alias entry. Preclinical View Profile https://www.bodyhackguide.co/compound/n-acetyl-semax ### Noopept + Choline Chloride Blend Cognitive Blend has no clinical trials; component evidence ranges from preclinical (Noopept) to small human RCTs (choline sources). A community nootropic stack pairing Noopept, a potent racetam-family dipeptide, with a choline source (commonly alpha-GPC, CDP-choline/citicoline, or choline bitartrate). t½ Not a single-molecule value - this is a two-component stack. Noopept has a short plasma half-life, with central effects that outlast blood levels; the rise in brain choline from alpha-GPC or CDP-choline persists for several hours. Noopept 10-30 mg (10,000-30,000 mcg)/day; choline source 150-600 mg/day (alpha-GPC) or 250-500 mg/day (CDP-choline). The blend has no validated dosing - ranges are extrapolated from single-component use. Preclinical View Profile https://www.bodyhackguide.co/compound/noopept-choline-blend ## Controlled Substances (1) Research compounds in the Controlled Substances family, compiled from peer-reviewed literature and clinical trial registries. ### Clenbuterol Controlled Substances Preclinical Clenbuterol is a long-acting, selective beta-2 adrenergic receptor agonist originally developed in the late 1970s by Thomae GmbH (later Boehringer Ingelheim) as a bronchodilator for obstructive airway disease. Preclinical View Profile https://www.bodyhackguide.co/compound/clenbuterol ## Energy & Performance (1) Research compounds in the Energy & Performance family, compiled from peer-reviewed literature and clinical trial registries. ### DMHA Energy & Performance Historical pharmaceutical; no modern clinical trials DMHA (octodrine) - chemically 2-amino-6-methylheptane, also sold as 2-aminoisoheptane or 1,5-dimethylhexylamine - is an aliphatic-amine central nervous system stimulant and a close structural analog of DMAA (1,3-dimethylamylamine). t½ Not formally characterized in humans. After ingestion, octodrine is rapidly metabolized to heptaminol, which becomes the predominant compound detected in blood and urine within hours [PMID:39401652]. Users commonly report perceptible stimulant effects lasting roughly 3-6 hours, but this is anecdotal rather than measured pharmacokinetics. 75-200 mg per dose (anecdotal pre-workout range; ~75,000-200,000 mcg). Historical pharmaceutical unit dose was 8-33 mg. No approved or clinically validated dose exists. Preclinical View Profile https://www.bodyhackguide.co/compound/dmha ## Enzyme (1) Research compounds in the Enzyme family, compiled from peer-reviewed literature and clinical trial registries. ### Papain Enzyme Preclinical Papain is a proteolytic enzyme extracted from the milky latex of the unripe fruit of the papaya tree (Carica papaya), a tropical plant native to southern Mexico and Central America and now cultivated across the tropics. 41 PubMed View Profile https://www.bodyhackguide.co/compound/papain ## Essential Nutrient (1) Research compounds in the Essential Nutrient family, compiled from peer-reviewed literature and clinical trial registries. ### Choline Essential Nutrient Preclinical Choline is an essential nutrient that was classified as a B-vitamin in the 1990s (sometimes loosely called vitamin B4, though that designation is not official) after the Institute of Medicine formally designated it essential in 1998 and established adequate intake recommendations. Preclinical View Profile https://www.bodyhackguide.co/compound/choline ## Flavonoid (4) Research compounds in the Flavonoid family, compiled from peer-reviewed literature and clinical trial registries. ### Apigenin Flavonoid Preclinical Apigenin is a plant-derived flavone (4',5,7-trihydroxyflavone) that occurs widely in the plant kingdom as a constituent of leaves, flowers, and seeds. Preclinical View Profile https://www.bodyhackguide.co/compound/apigenin ### EGCG (Epigallocatechin Gallate) Flavonoid Preclinical Epigallocatechin gallate (EGCG) is the most abundant and biologically active catechin polyphenol in green tea (Camellia sinensis), typically constituting 50-80% of total catechins in dried green tea leaves. Preclinical View Profile https://www.bodyhackguide.co/compound/egcg ### Fisetin Flavonoid Preclinical Fisetin is a polyhydroxy flavonoid (3,3',4',7-tetrahydroxyflavone) that has emerged as one of the most extensively studied natural senolytic compounds and a candidate therapy for age-related disease. Preclinical View Profile https://www.bodyhackguide.co/compound/fisetin ### Quercetin Flavonoid Preclinical Quercetin is a polyhydroxylated flavonoid compound (chemically 3,3',4',5,7-pentahydroxyflavone) that occurs widely in edible plants as both the free aglycone and a family of glycosides including rutin (quercetin-3-O-rutinoside), isoquercitrin (quercetin-3-O-glucoside), quercitrin (quercetin-3-O-rhamnoside), and multiple related sugar-conjugated forms. Preclinical View Profile https://www.bodyhackguide.co/compound/quercetin ## Foundational (13) Research compounds in the Foundational family, compiled from peer-reviewed literature and clinical trial registries. ### Vitamin D Foundational Preclinical Vitamin D is a fat-soluble secosteroid hormone (functionally a hormone rather than a traditional vitamin) with profound and pleiotropic effects across virtually every major organ system. 86 PubMed View Profile https://www.bodyhackguide.co/compound/vitamin-d ### Vitamin C Foundational Preclinical Vitamin C (L-ascorbic acid) is a water-soluble essential vitamin that humans, unlike most other mammals, cannot synthesize endogenously due to an inactivating mutation in the gulonolactone oxidase (GULO) gene acquired approximately 61 million years ago in a primate ancestor. 51 PubMed View Profile https://www.bodyhackguide.co/compound/vitamin-c ### Selenium Foundational Preclinical Selenium is an essential trace mineral first recognized as toxic in livestock grazing on seleniferous soils in the American West (reported by Kit Carson's expedition in the 1850s) and only later, in 1957, identified as essential for mammalian life when Klaus Schwarz discovered it prevented liver necrosis in rats deficient in the newly-described "Factor 3." The subsequent decades revealed that selenium's essentiality derives from its incorporation into approximately 25 distinct selenoproteins in humans, where it appears as the 21st genetically-encoded amino acid selenocysteine (Sec, U) at specific active sites. 20 PubMed View Profile https://www.bodyhackguide.co/compound/selenium ### Omega-3 Fatty Acids Foundational Preclinical Omega-3 fatty acids represent one of the most thoroughly researched nutritional interventions of the past half-century, with thousands of clinical trials, dozens of major meta-analyses, regulatory approvals for specific pharmaceutical preparations, and foundational status in cardiovascular medicine, cognitive health, and inflammatory conditions. 12 PubMed View Profile https://www.bodyhackguide.co/compound/omega-3-fatty-acids ### Vitamin K2 Foundational Preclinical Vitamin K2 refers to the menaquinone family of fat-soluble vitamins—structurally distinct from but functionally related to vitamin K1 (phylloquinone, found in leafy greens). 2 PubMed View Profile https://www.bodyhackguide.co/compound/vitamin-k2 ### Magnesium Foundational Preclinical Magnesium is the fourth most abundant cation in the human body and the second most abundant intracellular cation after potassium, with approximately 25 grams present in a typical adult—roughly 60% stored in bone, 27% in muscle, 6-7% in other soft tissues, and less than 1% in extracellular fluid including serum. 1 PubMed View Profile https://www.bodyhackguide.co/compound/magnesium ## GH Secretagogue (1) Research compounds in the GH Secretagogue family, compiled from peer-reviewed literature and clinical trial registries. ### CJC-1295 No-DAC (Mod GRF 1-29) GH Secretagogue Preclinical / Research peptide CJC-1295 No-DAC (also known as Mod GRF 1-29) is a 29-amino-acid synthetic peptide modeled on the active N-terminal fragment of human Growth Hormone Releasing Hormone (GHRH 1-29). t½ ~30 minutes (no DAC means no extended binding) 100 mcg per dose, 2-3x daily Preclinical View Profile https://www.bodyhackguide.co/compound/cjc-1295-no-dac ## GLP-1 / Glucagon Dual Agonist (1) Research compounds in the GLP-1 / Glucagon Dual Agonist family, compiled from peer-reviewed literature and clinical trial registries. ### Survodutide GLP-1 / Glucagon Dual Agonist Phase 3 (SYNCHRONIZE trials) Survodutide (BI 456906) is a once-weekly subcutaneous dual GLP-1 / glucagon receptor agonist developed by Boehringer Ingelheim and Zealand Pharma. t½ ~100 hours (about 4 days), supporting once-weekly dosing 600-6000 mcg (0.6-6 mg) weekly research dosing 61 PubMed View Profile https://www.bodyhackguide.co/compound/survodutide ## Growth Hormone (1) Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds. ### CJC-1295/Ipamorelin Blend Growth Hormone Preclinical / early-stage (no combination trials) Pre-mixed GHRH + GHRP blend for synergistic growth hormone release via dual-receptor stimulation.. t½ CJC-1295 as mod GRF 1-29 (no DAC): ~30 minutes. Ipamorelin: ~2 hours. The long-acting CJC-1295 with DAC is far longer - an estimated 5.8-8.1 days in its Phase I characterization [PMID:16352683] - but standard blends use the short-acting no-DAC form. Not human dosing guidance. Vendor blends are typically pre-mixed at a fixed ratio - commonly around 100 mcg CJC-1295 (mod GRF 1-29) to 100-200 mcg Ipamorelin per unit. Community-reported figures only; no clinically established dose exists. Preclinical View Profile https://www.bodyhackguide.co/compound/cjc-ipa-blend ## Growth Hormone / IGF-1 Axis (11) ### GHRP-2 Growth Hormone / IGF-1 Axis Phase 2 GHRP-2 (growth hormone-releasing peptide-2), also known as pralmorelin and KP-102, is a synthetic hexapeptide growth hormone secretagogue that was among the first GHRPs developed in the seminal research of Cyril Bowers and colleagues at Tulane University in the late 1980s and early 1990s. t½ ~15-30 minutes 100–300 mcg per injection 212 PubMed View Profile https://www.bodyhackguide.co/compound/ghrp-2 ### Sermorelin Growth Hormone / IGF-1 Axis FDA Approved Sermorelin acetate is a synthetic 29-amino-acid peptide corresponding to the biologically active N-terminal fragment of human growth hormone-releasing hormone (GHRH 1-29). t½ ~10-20 minutes (plasma; native GHRH 7 minutes) 198 PubMed View Profile https://www.bodyhackguide.co/compound/sermorelin ### GHRP-6 Growth Hormone / IGF-1 Axis Phase 2 GHRP-6 (growth hormone-releasing peptide-6) is a synthetic hexapeptide with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 that binds the ghrelin receptor (GHS-R1a) to stimulate endogenous growth hormone release. t½ ~20–30 minutes 100–300 mcg per injection 156 PubMed View Profile https://www.bodyhackguide.co/compound/ghrp-6 ### MK-677 (Ibutamoren) Growth Hormone / IGF-1 Axis Phase 2 MK-677 (also called Ibutamoren or Nutrobal) is an orally-active, non-peptide ghrelin receptor (GHS-R1a) agonist developed by Merck Research Laboratories in the 1990s. t½ ~24 hours (oral) 10,000–25,000 mcg (10–25 mg) oral daily 46 PubMed View Profile https://www.bodyhackguide.co/compound/mk-677 ### IGF-1 LR3 Growth Hormone / IGF-1 Axis Phase 2 IGF-1 LR3 (Long R3 IGF-1) is a synthetic analog of human insulin-like growth factor 1 modified at two positions to dramatically extend its serum half-life and amplify its tissue bioactivity compared to native IGF-1. t½ 20-30 hours (community/vendor estimate; no published human PK study of IGF-1 LR3) vs ~12 minutes for native IGF-1 20-80 mcg per day 40 PubMed View Profile https://www.bodyhackguide.co/compound/igf-1-lr3 ### CJC-1295 (Mod GRF 1-29) Growth Hormone / IGF-1 Axis Preclinical CJC-1295 without DAC (also called Modified GRF 1-29 or MOD-GRF 1-29) is a 30-amino-acid analog of the first 29 residues of endogenous Growth Hormone Releasing Hormone (GHRH), with four strategic substitutions (D-Ala² for DPP-4 resistance, Gln⁸, Ala¹⁵, Leu²⁷) that extend its plasma half-life from <2 minutes (native GHRH) to ~30 minutes. t½ ~30 minutes (without DAC / MOD-GRF 1-29); ~6-8 days (with DAC, due to covalent albumin binding) Without DAC: 100-300 mcg subcutaneous 1-3x daily (typically pre-bedtime); With DAC: 1000-2000 mcg subcutaneous once weekly 29 PubMed View Profile https://www.bodyhackguide.co/compound/cjc-1295 ## Hepatoprotective Flavonolignan (1) Research compounds in the Hepatoprotective Flavonolignan family, compiled from peer-reviewed literature and clinical trial registries. ### Silymarin Hepatoprotective Flavonolignan Preclinical Silymarin is the standardized flavonolignan complex extracted from the seeds (technically the fruit, or achenes) of milk thistle — Silybum marianum — a thistle native to the Mediterranean basin now naturalized across Europe, North Africa, North and South America, and Australia. 5,824 PubMed View Profile https://www.bodyhackguide.co/compound/silymarin ## Herbal (8) Research compounds in the Herbal family, compiled from peer-reviewed literature and clinical trial registries. ### Beta-Sitosterol Herbal Preclinical Beta-sitosterol (β-sitosterol) is the most abundant plant sterol in human diets and nature, structurally similar to cholesterol but with an ethyl group addition at C-24 position, making it a phytosterol rather than a zoosterol. 5,651 PubMed View Profile https://www.bodyhackguide.co/compound/beta-sitosterol ### Piperine Herbal Preclinical Piperine is the pungent alkaloid of black pepper (Piper nigrum) — the compound responsible for pepper's characteristic heat and aroma — and it has become one of the single most important adjuvants in the modern supplement industry not because of any direct clinical effect of its own, but because of its notable ability to increase the oral bioavailability of dozens of co-administered drugs, herbs, and nutrients. 2,234 PubMed View Profile https://www.bodyhackguide.co/compound/piperine ### Grape Seed Extract Herbal Preclinical Grape Seed Extract (GSE) — the lipid-soluble polyphenol-rich concentrate derived from the seeds of the common wine grape (Vitis vinifera, family Vitaceae) — is one of the most widely sold, most extensively researched, and most commercially heterogeneous botanical antioxidant products in the global supplement market. 908 PubMed View Profile https://www.bodyhackguide.co/compound/grape-seed-extract ### Saw Palmetto Herbal Preclinical Saw palmetto (Serenoa repens) is a small palm native to the southeastern United States whose berries have been used medicinally for over a century for urogenital conditions. 740 PubMed View Profile https://www.bodyhackguide.co/compound/saw-palmetto ### Maitake Herbal Preclinical Maitake (Grifola frondosa) is a large, fan-shaped polypore fungus native to the temperate hardwood forests of Japan, China, Korea, and parts of northeastern North America and Europe. 715 PubMed View Profile https://www.bodyhackguide.co/compound/maitake ### Boswellia Herbal Preclinical Boswellia — the aromatic gum resin of the tree Boswellia serrata, known in Ayurvedic tradition as Shallaki or Salai guggul and in English as Indian frankincense — is one of the best-characterized non-NSAID anti-inflammatory botanicals in the modern clinical literature, and one of the few whose mechanism is sufficiently well-understood at the molecular level to justify most of its clinical positioning. 200 PubMed View Profile https://www.bodyhackguide.co/compound/boswellia ## Hormonal (1) Research compounds in the Hormonal family, compiled from peer-reviewed literature and clinical trial registries. ### HCG Hormonal FDA-approved Human chorionic gonadotropin (hCG) is a 237-amino-acid glycoprotein hormone produced naturally during pregnancy by trophoblast cells of the developing embryo, beginning as early as 6-8 days after conception and peaking between weeks 8-11 of gestation at concentrations of 50,000-300,000 mIU/mL maternal serum. t½ Approximately 24-36 hours (terminal elimination). Clearance is biphasic: an initial distribution phase of roughly 6-11 hours followed by a terminal phase averaging ~33 hours. This is far longer than pituitary LH (~20-30 minutes), owing to the beta-subunit C-terminal peptide (CTP) and heavy sialylation. Peak plasma concentration occurs ~6-12 hours after SC or IM injection, and a single dose exerts biological effects for roughly 5-7 days. Elimination is primarily renal. Preclinical View Profile https://www.bodyhackguide.co/compound/hcg ## Hormone (1) ### DHEA Hormone Preclinical DHEA (dehydroepiandrosterone) is an endogenous steroid hormone synthesized primarily by the adrenal cortex (zona reticularis), with smaller amounts produced by the gonads and brain. 4,979 PubMed View Profile https://www.bodyhackguide.co/compound/dhea ## Hormone Support (2) ### Enclomiphene Hormone Support Phase III Enclomiphene citrate (ENC, Androxal, trans-clomiphene) is the pure trans-isomer of clomiphene citrate, a non-steroidal selective estrogen receptor modulator (SERM) developed originally by Repros Therapeutics for the treatment of secondary (hypogonadotropic) hypogonadism in men who want to preserve fertility. t½ ~10 hours 6,250–25,000 mcg (6.25–25 mg) oral daily 95 PubMed View Profile https://www.bodyhackguide.co/compound/enclomiphene ### T3/T4 Thyroid Blend Hormone Support Components are FDA-approved prescription drugs (levothyroxine and liothyronine); the fixed-ratio synthetic T3/T4 combination product is investigational/unapproved as sold and is framed here strictly for research use only (RUO). A T3/T4 blend pairs two real, FDA-approved thyroid hormones - levothyroxine (T4) and liothyronine (T3) - in a single product, intended to more closely mimic the thyroid gland's natural output than T4 alone. t½ T4 (levothyroxine): approximately 6-7 days in euthyroid adults (longer in hypothyroid, shorter in hyperthyroid states). T3 (liothyronine): approximately 1 day (~18-24 hours), which is why T3 is dosed multiple times daily or as a slow-release preparation. Component-split and physician-set, not a fixed self-dose: T4 (levothyroxine) approximately 75-150 mcg/day and T3 (liothyronine) approximately 5-20 mcg/day divided - both titrated to labs (TSH, free T4, free T3), individualized by weight, age and cardiac status. Not a self-dosing recommendation. Preclinical View Profile https://www.bodyhackguide.co/compound/t3-t4-blend ## Hormones & Endocrine (Non-GH) (4) ### Oxytocin Hormones & Endocrine (Non-GH) FDA Approved Oxytocin is a nine-amino-acid cyclic peptide hormone (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2) synthesized in magnocellular neurons of the hypothalamic paraventricular (PVN) and supraoptic nuclei (SON), then transported along axons to the posterior pituitary for release into systemic circulation. t½ ~1-6 minutes (plasma); central/behavioral effects outlast plasma clearance, typically ~30-120 minutes after intranasal dosing 602 PubMed View Profile https://www.bodyhackguide.co/compound/oxytocin ### Kisspeptin-10 Hormones & Endocrine (Non-GH) Phase 2 Kisspeptin-10 (KP-10, metastin 45-54) is the C-terminal decapeptide fragment of kisspeptin, a neuropeptide product of the KISS1 gene that has emerged over the past two decades as the master regulator of reproductive endocrinology in humans and all other vertebrates studied to date. t½ ~4 minutes (KP-10, plasma) - reflecting rapid peptidase degradation. The downstream LH/FSH response nonetheless persists ~1-2 hours after a dose. For comparison, kisspeptin-54 has a measured plasma half-life of ~27 minutes. 597 PubMed View Profile https://www.bodyhackguide.co/compound/kisspeptin-10 ### Gonadorelin Gonadorelin is the synthetic, pharmaceutically manufactured version of endogenous gonadotropin-releasing hormone (GnRH) — a ten-amino-acid decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) first isolated, sequenced, and synthesized by Andrew V. t½ ~2-10 minutes (plasma; rapid enzymatic degradation by peptidases) 100-300 mcg 473 PubMed View Profile https://www.bodyhackguide.co/compound/gonadorelin ### HMG (Human Menopausal Gonadotropin) HMG, or human menopausal gonadotropin, is not a synthetic research chemical. t½ Elimination half-life for follicle-stimulating hormone of 11 to 13 hours in the multiple-dose phase, similar for subcutaneous and intramuscular routes (Menopur US prescribing information) Preclinical View Profile https://www.bodyhackguide.co/compound/hmg ## Immune & Inflammation (3) Research compounds in the Immune & Inflammation family, compiled from peer-reviewed literature and clinical trial registries. ### LL-37 Immune & Inflammation Phase 2 LL-37 is the only human cathelicidin, a 37-amino-acid amphipathic alpha-helical peptide (LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES) cleaved from the C-terminus of the 170-amino-acid precursor hCAP-18 (human cationic antimicrobial protein, 18 kDa), which is encoded by the CAMP gene on chromosome 3p21.31. t½ ~30 minutes (free peptide; rapidly cleared by proteolysis). Human pharmacokinetics of exogenous LL-37 are not well characterized. 3,029 PubMed View Profile https://www.bodyhackguide.co/compound/ll-37 ### Thymosin Alpha-1 (TA1) Immune & Inflammation FDA Approved Thymosin alpha-1 (Tα1) is a 28-amino-acid N-acetylated peptide (N-Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn) isolated and characterized by Allan Goldstein's laboratory at George Washington University in the 1970s as the immunologically active cleavage product of a larger precursor (prothymosin alpha) found in thymic tissue. t½ ~2 hours 1,600 mcg (1.6 mg) per injection (standard clinical dose) 701 PubMed View Profile https://www.bodyhackguide.co/compound/thymosin-alpha-1 ### Larazotide (AT-1001) Immune & Inflammation Phase 3 Larazotide is an eight amino acid peptide with the sequence glycine-glycine-valine-leucine-valine-glutamine-proline-glycine, usually supplied as the acetate salt. t½ Not established as a systemic value. Larazotide is designed to act locally in the intestinal lumen and is given orally rather than for systemic exposure (PMID: 33881350); single-dose safety, tolerance and pharmacokinetics were assessed in a phase 1b study in celiac disease subjects (PMID: 17697209) Preclinical View Profile https://www.bodyhackguide.co/compound/larazotide ## Injury, Repair & Recovery (2) Research compounds in the Injury, Repair & Recovery family, compiled from peer-reviewed literature and clinical trial registries. ### TB-500 Injury, Repair & Recovery Phase 2 TB-500 is the name the market and the FDA use for a short synthetic fragment of thymosin beta-4: the seven-amino-acid, N-acetylated actin-binding sequence Ac-LKKTETQ (residues 17 to 23). t½ Plasma half-life is short - full-length thymosin beta-4 clears on the order of hours, while the short LKKTETQ actin-binding fragment clears within minutes. Tissue-level regenerative effects persist substantially longer than plasma exposure. 2000-5000 mcg (2-5 mg) subcutaneous 2x weekly loading; 2000 mcg (2 mg) weekly maintenance 1,039 PubMed View Profile https://www.bodyhackguide.co/compound/tb-500 ### BPC-157 Injury, Repair & Recovery Preclinical BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a partial sequence of human gastric juice protein BPC. t½ Short plasma half-life. The first formal preclinical ADME study reported an elimination half-life under ~30 minutes after IV/IM dosing in rats and dogs, with linear dose-proportional kinetics (PMID: 36588717); a 2026 biopharmaceutical review confirms this sub-30-minute plasma half-life and highlights a pharmacokinetic-pharmacodynamic disconnect, as biological effects persist for hours to days (PMID: 42198317). No full human pharmacokinetic study has been published; twice-daily dosing is empirical/community-standard rather than PK-derived. 200-500 mcg subcutaneous 1-2x daily (community protocols); 1-10 mcg/kg in animal studies 214 PubMed View Profile https://www.bodyhackguide.co/compound/bpc-157 ## Isothiocyanate (1) Research compounds in the Isothiocyanate family, compiled from peer-reviewed literature and clinical trial registries. ### Sulforaphane Isothiocyanate Preclinical Sulforaphane is an organosulfur compound belonging to the isothiocyanate family, found predominantly in cruciferous vegetables (Brassicaceae family) including broccoli, broccoli sprouts, Brussels sprouts, cabbage, cauliflower, kale, bok choy, and collard greens. Preclinical View Profile https://www.bodyhackguide.co/compound/sulforaphane ## Liver Support (1) Research compounds in the Liver Support family, compiled from peer-reviewed literature and clinical trial registries. ### TUDCA Liver Support Preclinical TUDCA (tauroursodeoxycholic acid) is a hydrophilic bile acid formed by taurine conjugation of ursodeoxycholic acid (UDCA, the active ingredient in the widely-prescribed cholestasis medication Ursodiol). Preclinical View Profile https://www.bodyhackguide.co/compound/tudca ## Liver/Digestive (1) Research compounds in the Liver/Digestive family, compiled from peer-reviewed literature and clinical trial registries. ### Ovagen Liver/Digestive Preclinical Ovagen is a short synthetic peptide developed in Russia by Vladimir Khavinson and collaborators at the St. t½ Not established - no human or animal pharmacokinetic data have been published. As a small, unprotected tripeptide, EDL is expected to be hydrolysed by peptidases within minutes in the circulation. No validated human dose. Khavinson cytomax convention for oral short peptides is about 10 mg once daily in 10-day courses; research suppliers of the lyophilised synthetic EDL tripeptide list roughly 1-2 mg subcutaneously daily. These are conventions, not trial-derived figures. 19 PubMed View Profile https://www.bodyhackguide.co/compound/ovagen ## Longevity (4) Research compounds in the Longevity family, compiled from peer-reviewed literature and clinical trial registries. ### NAD+ Longevity Phase II NAD+ (nicotinamide adenine dinucleotide, oxidized form) is a pyridine dinucleotide coenzyme essential to energy metabolism, DNA repair via PARP enzymes, sirtuin-mediated gene regulation, and calcium signaling via CD38. t½ Varies by form: NR ~8 hours plasma; NMN ~1-2 hours plasma; IV NAD+ infusion dose-dependent Oral precursors: NR 300-2,000 mg/day, NMN 250-900 mg/day, NAM 500-1,500 mg/day; IV NAD+ 500-1,500 mg per session. 3,197 PubMed View Profile https://www.bodyhackguide.co/compound/nad ### Cortagen Longevity Preclinical Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) from the Khavinson bioregulator family developed at the St. t½ Unknown (tetrapeptide; estimated <4 hours) Preclinical View Profile https://www.bodyhackguide.co/compound/cortagen ### NMN Longevity Preclinical Nicotinamide mononucleotide (NMN) is a naturally occurring nucleotide derived from ribose and nicotinamide, serving as the direct biosynthetic precursor to nicotinamide adenine dinucleotide (NAD+) via a single enzymatic step catalyzed by nicotinamide mononucleotide adenylyltransferase (NMNAT). Preclinical View Profile https://www.bodyhackguide.co/compound/nmn ### Rapamycin Longevity Preclinical Rapamycin is a macrocyclic lactone antibiotic discovered in 1972 in soil samples from Rapa Nui (Easter Island) by a bacteriology survey team investigating indigenous Streptomyces species. Preclinical View Profile https://www.bodyhackguide.co/compound/rapamycin ## Longevity & Cellular Health (2) Research compounds in the Longevity & Cellular Health family, compiled from peer-reviewed literature and clinical trial registries. ### MOTS-c Longevity & Cellular Health Preclinical MOTS-c (Mitochondrial ORF of the Twelve S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide — a member of a recently discovered class of small peptides encoded in mitochondrial DNA rather than nuclear DNA. t½ ~4–6 hours 5,000–10,000 mcg (5–10 mg) per injection 167 PubMed View Profile https://www.bodyhackguide.co/compound/mots-c ### Epithalon Longevity & Cellular Health Preclinical Epithalon (also spelled Epitalon, sequence Ala-Glu-Asp-Gly / AEDG) is a synthetic tetrapeptide designed by Prof. t½ Not well characterized in humans. As a small tetrapeptide, AEDG is expected to have a very short plasma half-life (on the order of minutes), while downstream gene-expression and circadian effects are thought to persist considerably longer. Any specific half-life figure should be treated as an unvalidated estimate. 5000-10000 mcg (5-10 mg) subcutaneous daily for 10-20 day cycles; typically repeated 1-2 times per year in anti-aging protocols 1 PubMed View Profile https://www.bodyhackguide.co/compound/epithalon ## Metabolic (9) Research compounds in the Metabolic family, compiled from peer-reviewed literature and clinical trial registries. ### Tadalafil Metabolic Preclinical Tadalafil is a selective inhibitor of phosphodiesterase type 5 (PDE5), an enzyme that hydrolyzes cyclic guanosine monophosphate (cGMP) into non-cyclic 5'-GMP. 1 PubMed View Profile https://www.bodyhackguide.co/compound/tadalafil ### AICAR (acadesine) Metabolic Phase 3 AICAR is a nucleoside analog of adenosine. t½ Intact acadesine was measurable in plasma for only about 2 hours after a short intravenous infusion in four healthy men, with total plasma clearance of 2.2 L/h/kg and negligible protein binding; radiolabeled drug-derived material had an apparent terminal half-life of about one week, reflecting metabolites rather than parent compound (PMID: 8227467) Preclinical View Profile https://www.bodyhackguide.co/compound/aicar ### Amlexanox Metabolic FDA Approved Amlexanox is an old anti-inflammatory drug with a second life. t½ Not established in published human pharmacokinetic studies for the oral capsule form; a validated plasma assay has been used for preclinical pharmacokinetics in rats (PMID: 34842293) Preclinical View Profile https://www.bodyhackguide.co/compound/amlexanox ### Berberine Metabolic Preclinical Berberine is an isoquinoline alkaloid — a naturally occurring plant secondary metabolite with a characteristic yellow color — extracted from the roots, rhizomes, stems, and bark of several plant genera including Berberis (barberry, Oregon grape), Coptis (goldthread), Hydrastis (goldenseal), Phellodendron (Amur cork tree), and Tinospora (guduchi). Preclinical View Profile https://www.bodyhackguide.co/compound/berberine ### Cardarine (GW501516) Metabolic Discontinued Cardarine is the market name for GW501516, a synthetic agonist of the nuclear receptor PPAR-delta developed by GlaxoSmithKline as a treatment for low HDL cholesterol and the lipid problems that travel with metabolic syndrome. t½ Not reported in the published human trials; the phase 1 and phase 2 studies described lipid outcomes over two to twelve weeks of oral dosing without publishing a terminal half-life (PMID: 17110604; PMID: 22814748) Preclinical View Profile https://www.bodyhackguide.co/compound/cardarine ### Metformin Metabolic Preclinical Metformin is a biguanide-class oral antihyperglycemic medication that has been in continuous clinical use since 1957 (in France under the brand name Glucophage) and is now the most-prescribed diabetes medication worldwide with over 150 million prescriptions annually. Preclinical View Profile https://www.bodyhackguide.co/compound/metformin ## Metabolic & Weight Loss (7) Research compounds in the Metabolic & Weight Loss family, compiled from peer-reviewed literature and clinical trial registries. ### Semaglutide Metabolic & Weight Loss FDA Approved Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) with a molecular weight of 4113.58 Da and CAS number 910463-68-2. t½ ~7 days (168 hours), enabled by C18 fatty diacid albumin-binding modification Diabetes (Ozempic): 250-1000 mcg weekly; Weight management (Wegovy): 2400 mcg weekly (after 16-week titration); Oral (Rybelsus): 3-14 mg daily 3,273 PubMed View Profile https://www.bodyhackguide.co/compound/semaglutide ### Tirzepatide Metabolic & Weight Loss FDA Approved Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist with a molecular weight of 4813.45 Da and CAS number 2023788-19-2. t½ ~5 days (approximately 120 hours), enabled by C20 fatty diacid albumin-binding modification 2500 mcg (2.5 mg) starting dose, titrated every 4 weeks through 5000, 7500, 10000, 12500, to 15000 mcg (15 mg) maximum weekly dose 626 PubMed View Profile https://www.bodyhackguide.co/compound/tirzepatide ### Retatrutide Metabolic & Weight Loss Phase 3 Retatrutide (also coded LY3437943) is an investigational once-weekly triple-agonist at the GLP-1, GIP, and glucagon receptors. t½ ~6 days (plasma, albumin-bound) 1,000–12,000 mcg (1–12 mg) per week 135 PubMed View Profile https://www.bodyhackguide.co/compound/retatrutide ### Cagrilintide Metabolic & Weight Loss Phase 3 Cagrilintide (also known as AM833, development code NN9838) is a long-acting amylin analog developed by Novo Nordisk as a next-generation weight-management therapy, designed to be co-administered with the GLP-1 receptor agonist semaglutide in a fixed-ratio combination known as CagriSema. t½ ~159 hours (approximately 7 days) 46 PubMed View Profile https://www.bodyhackguide.co/compound/cagrilintide ### HGH Fragment 176-191 Metabolic & Weight Loss Phase 2 HGH Fragment 176-191 (also written HGH Frag 176-191, hGH Fragment 176-191, and frequently appearing in clinical literature as AOD-9604 — "Anti-Obesity Drug 9604") is a synthetic peptide corresponding to the C-terminal 15-amino-acid region of the 191-amino-acid human growth hormone (hGH) molecule, with an additional N-terminal tyrosine residue added for stability and biological activity. t½ ~30 minutes (short plasma half-life) 250-500 mcg 2 PubMed View Profile https://www.bodyhackguide.co/compound/hgh-frag-176-191 ### AOD-9604 Metabolic & Weight Loss Phase 3 AOD-9604 (Anti-Obesity Drug 9604) is a synthetic 16-amino-acid peptide fragment of human growth hormone (hGH) corresponding to residues 177-191 of the hGH molecule plus a tyrosine addition at the N-terminus (sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe). t½ ~30–60 minutes 250–600 mcg per injection 1 PubMed View Profile https://www.bodyhackguide.co/compound/aod-9604 ## Mineral (8) Research compounds in the Mineral family, compiled from peer-reviewed literature and clinical trial registries. ### Chromium Mineral Preclinical Chromium is a transition metal that occupies one of the more peculiar positions in human nutrition: long marketed as essential for carbohydrate metabolism and insulin sensitization, the evidence for chromium essentiality has progressively softened over the past two decades, and both the European Food Safety Authority (EFSA 2014) and multiple independent reviews have concluded that chromium III is not definitively essential for humans. 1,578 PubMed View Profile https://www.bodyhackguide.co/compound/chromium ### Manganese Mineral Preclinical Manganese is an essential trace mineral and redox-active transition metal occupying a peculiar place in human nutrition: absolutely required at milligram doses for mitochondrial antioxidant defense, gluconeogenesis, urea cycle function, and connective tissue synthesis — yet potently neurotoxic at the hundredfold-higher doses encountered occupationally (welders, miners, battery workers) and in patients on long-term parenteral nutrition with inadequately controlled trace mineral content. 1,523 PubMed View Profile https://www.bodyhackguide.co/compound/manganese ### Calcium Mineral Preclinical Calcium is the most abundant mineral in the human body — roughly 1,000 to 1,500 grams in a 70 kg adult, with 99% sequestered in the skeleton and teeth as crystalline hydroxyapatite [Ca10(PO4)6(OH)2], and the remaining 1% distributed across extracellular fluid, intracellular cytoplasm, mitochondria, and the endoplasmic/sarcoplasmic reticulum. 1,288 PubMed View Profile https://www.bodyhackguide.co/compound/calcium ### Molybdenum Mineral Preclinical Molybdenum is an essential trace mineral that functions as the catalytic metal center of a small but critical set of mammalian enzymes — xanthine oxidase/dehydrogenase, aldehyde oxidase, sulfite oxidase, and mitochondrial amidoxime reducing component (mARC) — all of which carry a shared prosthetic group called the molybdenum cofactor (moco, molybdopterin-Mo complex). 948 PubMed View Profile https://www.bodyhackguide.co/compound/molybdenum ### Boron Mineral Preclinical Boron is an ultra-trace element whose nutritional status in humans sits in a distinctive regulatory gray zone: the Institute of Medicine (US) has not established a recommended dietary allowance (RDA) or estimated average requirement (EAR) for boron because the evidence for essentiality in humans does not meet the strict criteria applied to calcium, iron, or zinc, yet the IOM, the European Food Safety Authority (EFSA), and the World Health Organization (WHO) all set tolerable upper intake levels (ULs) — implicitly acknowledging that boron has biological activity and dose-response safety concerns. 322 PubMed View Profile https://www.bodyhackguide.co/compound/boron ### Copper Mineral Preclinical Copper is an essential trace mineral that most adults get in adequate amounts from a varied omnivorous diet — but that routinely drops into functional insufficiency when people take long-term high-dose zinc supplements, consume highly processed diets, undergo bariatric surgery, or use copper-chelating therapies. Preclinical View Profile https://www.bodyhackguide.co/compound/copper ## Mitochondrial Peptides (1) ### SS-31 Mitochondrial Peptides Clinical/Approved SS-31 (elamipretide; MTP-131; formerly Bendavia; chemical sequence D-Arg-Dmt-Lys-Phe-NH2 with dimethyltyrosine at position 2) is a first-in-class aromatic-cationic tetrapeptide designed to selectively target the inner mitochondrial membrane and bind cardiolipin, the signature mitochondrial phospholipid essential for cristae architecture, electron transport chain organization, and respiratory function. t½ ~2-4 hours (plasma, after subcutaneous injection); tissue residence is longer due to cardiolipin binding 20-60 mg 4 PubMed View Profile https://www.bodyhackguide.co/compound/ss-31 ## Mitochondrial Support (1) Research compounds in the Mitochondrial Support family, compiled from peer-reviewed literature and clinical trial registries. ### Urolithin A Mitochondrial Support Preclinical Urolithin A (3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one; trade name Mitopure from Timeline Nutrition, formerly Amazentis) is a gut-microbiome-derived metabolite of dietary ellagitannins — polyphenolic compounds found in pomegranates, walnuts, strawberries, raspberries, and several other berries. 7 PubMed View Profile https://www.bodyhackguide.co/compound/urolithin-a ## Myostatin Inhibitor (1) Research compounds in the Myostatin Inhibitor family, compiled from peer-reviewed literature and clinical trial registries. ### Follistatin-344 Myostatin Inhibitor Preclinical / Research peptide Follistatin-344 is a 344-amino-acid glycoprotein that binds and neutralizes myostatin (GDF-8) - the primary negative regulator of skeletal muscle growth. t½ Short; native follistatin protein is cleared rapidly (minutes to a few hours in vivo). No formal pharmacokinetic data exist for injected Follistatin-344 (FST-344). 50-100 mcg 445 PubMed View Profile https://www.bodyhackguide.co/compound/follistatin-344 ## Nootropic (7) Cognitive-enhancing compounds studied for memory, focus, learning, and neuroprotection. Includes racetams, cholinergics like Alpha-GPC, amino-acid derivatives like L-Theanine, and plant adaptogens like Bacopa Monnieri. ### Caffeine Nootropic Preclinical Caffeine (1,3,7-trimethylxanthine) is a natural methylxanthine alkaloid found in the seeds, fruits, leaves, and bark of over 60 plant species — most notably Coffea (coffee), Camellia sinensis (tea), Theobroma cacao (cacao), Paullinia cupana (guaraná), Ilex paraguariensis (yerba mate), and Cola acuminata (kola nut). 4,235 PubMed View Profile https://www.bodyhackguide.co/compound/caffeine ### Inositol Nootropic Preclinical Inositol is a naturally-occurring cyclic sugar alcohol (cyclohexanehexol) that functions as a critical structural component of cell membranes and a second-messenger precursor in intracellular signaling. 3,870 PubMed View Profile https://www.bodyhackguide.co/compound/inositol ### L-Tryptophan Nootropic Preclinical L-Tryptophan is one of the nine essential amino acids — meaning the human body cannot synthesize it and must obtain it from dietary protein — and is the direct metabolic precursor to serotonin, melatonin, and (via a separate route) the vitamin niacin (nicotinamide / NAD+). 3,217 PubMed View Profile https://www.bodyhackguide.co/compound/l-tryptophan ### Magnesium L-Threonate Nootropic Preclinical Magnesium L-Threonate is a proprietary chelated form of magnesium in which the magnesium cation is bound to L-threonic acid — a metabolite of ascorbic acid (vitamin C) — forming the salt commonly marketed under the brand name Magtein. 207 PubMed View Profile https://www.bodyhackguide.co/compound/magnesium-l-threonate ### CDP-Choline Nootropic Phase 4 CDP-choline (cytidine 5'-diphosphocholine, pharmaceutical name citicoline) is a naturally occurring intracellular intermediate in the Kennedy pathway for phosphatidylcholine synthesis — the primary biochemical route by which all nucleated cells produce the dominant membrane phospholipid. 56 PubMed View Profile https://www.bodyhackguide.co/compound/cdp-choline ### Alpha-GPC Nootropic Phase 4 Alpha-GPC (chemical name L-alpha-glycerylphosphorylcholine; pharmaceutical name choline alfoscerate) is a naturally occurring cholinergic compound that serves as a highly bioavailable precursor to both acetylcholine (the primary neurotransmitter of the cholinergic system, central to learning, memory, attention, and neuromuscular function) and phosphatidylcholine (the principal phospholipid building block of neuronal cell membranes). 9 PubMed View Profile https://www.bodyhackguide.co/compound/alpha-gpc ## Nootropic Adaptogen (1) ### Bacopa monnieri Nootropic Adaptogen Preclinical Bacopa monnieri is a creeping, succulent-leaved aquatic perennial that grows in wetlands, bogs, and rice paddies across the Indian subcontinent, Southeast Asia, northern Australia, and the southern United States. 400 PubMed View Profile https://www.bodyhackguide.co/compound/bacopa-monnieri ## Nootropic Lipid (1) ### Oleamide Nootropic Lipid Preclinical Oleamide is a fatty acid primary amide that your brain naturally produces during sleep deprivation — your body's endogenous sleep-promoting lipid signal. t½ ~30-60 minutes (rapidly metabolized by FAAH) 62 PubMed View Profile https://www.bodyhackguide.co/compound/oleamide ## Nootropic Peptide (9) ### Cerebrolysin Nootropic Peptide Clinical Cerebrolysin is a porcine brain-derived peptide complex developed by EVER Neuro Pharma (Austria) — a low-molecular-weight neurotrophic preparation containing a mixture of free amino acids and bioactive peptides extracted from purified pig brain proteins. t½ ~2-4 hours (multi-component peptide mix) 85 PubMed View Profile https://www.bodyhackguide.co/compound/cerebrolysin ### Cortexin Nootropic Peptide Marketed in Russia/CIS (Geropharm); human clinical use with limited-quality evidence (small, mostly Russian-language studies; no Western RCT; not FDA/EMA approved) Cortexin is a purified peptide preparation extracted from cattle and pig cerebral cortex tissue — a low-molecular-weight neuropeptide complex used clinically in Russia and Eastern Europe for cognitive impairment, post-stroke recovery, encephalopathy, attention disorders, and pediatric developmental conditions. Like Cerebrolysin, Cortexin is positioned as a broad-spectrum neurotrophic preparation supplying bioactive peptides that mimic endogenous neurotrophic factors. t½ ~2-3 hours (estimated from analog peptide preparations) 18 PubMed View Profile https://www.bodyhackguide.co/compound/cortexin ### P-21 Nootropic Peptide Preclinical P-21 is a synthetic cyclic dipeptide — Cyclo(L-prolyl-glycine) — derived from the Selank/Semax C-terminal Pro-Gly-Pro motif. t½ Not formally characterized in published work. P021 has only been studied in rodents (oral/dietary and subcutaneous dosing); no human pharmacokinetic data exist. 4 PubMed View Profile https://www.bodyhackguide.co/compound/p21 ### NA-Semax Nootropic Peptide Preclinical NA-Semax is the N-acetyl-l-aspartyl variant of Semax — the original ACTH(4-7) Pro-Gly-Pro analog developed at the Russian Academy of Sciences in the 1990s. t½ ~20-30 minutes (intranasal, estimated from analog data) 3 PubMed View Profile https://www.bodyhackguide.co/compound/na-semax ### NA-Semax Amidate Nootropic Peptide Preclinical NA-Semax Amidate is the C-terminally amidated NA-Semax — the carboxylic acid at the peptide's C-terminus is replaced with an amide group (-NH2), which is reported to further extend metabolic half-life by resisting carboxypeptidase cleavage in addition to the aminopeptidase resistance the N-acetyl group already provides. The practical effect is a peptide with dosing-frequency use: where standard Semax often requires 3-4 daily doses to maintain effect, NA-Semax Amidate is reported (in vendor monographs and community usage) to maintain subjective effects on a 1-2x daily schedule. t½ ~30-45 minutes (estimated, longer than standard Semax) 2 PubMed View Profile https://www.bodyhackguide.co/compound/na-semax-amidate ### P-21 Amidate Nootropic Peptide Preclinical P-21 Amidate is the amide-modified variant of P-21, the cyclic dipeptide derived from Selank. t½ No established human PK - unknown. P-21 (P021) is a preclinical compound; rodent studies used chronic oral or subcutaneous dosing and demonstrated oral bioavailability and blood-brain-barrier penetration, but no validated human half-life data exist. 1 PubMed View Profile https://www.bodyhackguide.co/compound/p21-amidate ## Nootropics (39) ### Methylene Blue Nootropics Preclinical Methylene blue (methylthioninium chloride) is a phenothiazine dye with a 150-year pharmacology record. 0.5 mg - 4 mg/kg daily (oral) 2,367 PubMed View Profile https://www.bodyhackguide.co/compound/methylene-blue ### L-Theanine Nootropics FDA Approved L-Theanine is a non-proteinogenic amino acid found almost exclusively in tea (Camellia sinensis) and a handful of edible mushrooms, and it has become the single most widely-used calm-focus nootropic in the modern supplement market — both on its own at 100-400mg doses and, even more prominently, as the classic 1:1 or 2:1 pair with caffeine that defines the "calm-focus" experiential signature of green tea and of virtually every serious nootropic stack. t½ 1-3 hours (plasma); central CNS effect 3-5 hours 1,226 PubMed View Profile https://www.bodyhackguide.co/compound/l-theanine ### Uridine Monophosphate (UMP) Nootropics Preclinical Uridine monophosphate (UMP, also written 5'-UMP or uridine-5'-monophosphate) is the nucleotide form of uridine, consisting of the pyrimidine base uracil linked to a ribose sugar phosphorylated at the 5' position. 920 PubMed View Profile https://www.bodyhackguide.co/compound/uridine-monophosphate ### Lion's Mane Mushroom Nootropics Phase 2 Lion's Mane (scientific name Hericium erinaceus; also known as yamabushitake in Japanese, houtou in Chinese, bearded tooth fungus, monkey head mushroom, and pom pom mushroom) is a white-to-cream coloured edible and medicinal mushroom in the tooth fungus family (Hericiaceae), characterised by its distinctive cascading spines that resemble a lion's mane or white cascading icicles. 554 PubMed View Profile https://www.bodyhackguide.co/compound/lions-mane ### Semax Nootropics Approved (Russia, since mid-1990s for stroke and cognitive disorders) Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro, MEHFPGP, 813 Da molecular weight) developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the 1980s. t½ ~2-3 minutes plasma half-life (functional neurological effects persist 12-24 hours due to BDNF/NGF gene expression changes) 100-900 mcg intranasal daily (0.1% solution: 2-3 drops per nostril 2-3x daily); 1% solution used for acute stroke in Russian clinical protocols 205 PubMed View Profile https://www.bodyhackguide.co/compound/semax ### Noopept Nootropics Russia Approved Noopept is the common brand and research name for N-phenylacetyl-L-prolylglycine ethyl ester (GVS-111; INN omberacetam), a small dipeptide nootropic developed in the 1990s at the Russian Academy of Medical Sciences' Institute of Pharmacology under Tatiana Voronina and Rita Ostrovskaya. 106 PubMed View Profile https://www.bodyhackguide.co/compound/noopept ## Other (10) Specialty research compounds spanning lipid modulators, longevity molecules, mitochondrial cofactors, and emerging translational targets. ### B7-33 Other Preclinical B7-33 is a single-chain, 26-amino-acid peptide engineered as a functionally selective agonist of the relaxin family peptide receptor 1 (RXFP1), designed to recapitulate the therapeutic activity of human H2 relaxin — the endogenous peptide hormone that is naturally elevated during pregnancy and has broad cardioprotective, vasodilatory, and anti-fibrotic effects. t½ In vitro serum-stability half-life is approximately 6 minutes; B7-33 is rapidly degraded (a lipidated analog extended this to ~60 minutes in the same assay). Human in vivo pharmacokinetics are unpublished, and rapid clearance is expected for a small linear peptide (Praveen et al. 2023, PMID 37047588). 500-4000 mcg subcutaneous per injection (community/self-report research doses; most commonly ~1000 mcg / 1 mg once daily). No validated human dose exists - all figures are empirical extrapolations from rodent pharmacology. 11 PubMed View Profile https://www.bodyhackguide.co/compound/b7-33 ### RU-58841 Other Preclinical RU-58841 (also known as PSK-3841 or HMR-3841, and commonly written simply as RU in hair-loss forums) is a non-steroidal androgen receptor antagonist originally developed by Roussel Uclaf (later absorbed into Sanofi) in the late 1980s and early 1990s. 25 mg - 50 mg topical daily (dissolved in vehicle) 11 PubMed View Profile https://www.bodyhackguide.co/compound/ru-58841 ### Aminotadalafil Other Preclinical Aminotadalafil is an unapproved research analog of tadalafil, the PDE5 inhibitor marketed under the brand name Cialis for erectile dysfunction and under Adcirca for pulmonary arterial hypertension. 2.5 mg - 20 mg (oral) 9 PubMed View Profile https://www.bodyhackguide.co/compound/aminotadalafil ### Prostamax Other Preclinical Prostamax is a short synthetic peptide developed in Russia by Vladimir Khavinson and collaborators at the St. t½ Not characterized in published pharmacokinetic literature 10 mg oral capsule, 1-2 daily for 10-30 days 6 PubMed View Profile https://www.bodyhackguide.co/compound/prostamax ### Testagen Other Preclinical Testagen is a short peptide bioregulator developed inside Vladimir Khavinson's laboratory at the Saint Petersburg Institute of Bioregulation and Gerontology and marketed in Russia as an oral capsule intended to support the male reproductive system — principally the testes, spermatogenesis, and the hypothalamic-pituitary-gonadal (HPG) axis. 20 mg oral capsule, 1-2 daily for 10 days per cycle 2 PubMed View Profile https://www.bodyhackguide.co/compound/testagen ### Diisopropylamine dichloroacetate (DADA) Other Approved (Japan) DADA is the abbreviation the research chemical market uses for diisopropylamine dichloroacetate, the diisopropylamine salt of dichloroacetic acid, CAS 660-27-5. Preclinical View Profile https://www.bodyhackguide.co/compound/dada ## Peptides (1) ### Thymalin Peptides Clinical (Russia-registered; not FDA-approved) Thymalin is a thymus-derived peptide complex developed in the 1970s by Vladimir Khavinson and the Leningrad (now St. t½ Short for the individual peptides in the mixture (on the order of minutes to a few hours). Biological effects persist for weeks to months after a 10-day course, which is why Thymalin is given in discrete courses rather than continuously. 5-15 mg 2 PubMed View Profile https://www.bodyhackguide.co/compound/thymalin ## Performance (7) Research compounds in the Performance family, compiled from peer-reviewed literature and clinical trial registries. ### ITPP Performance Preclinical ITPP (myo-inositol trispyrophosphate, sometimes written myo-inositol tripyrophosphate or OXY111A in NormOxys trial documents) is a small-molecule allosteric effector of hemoglobin designed to increase the amount of oxygen red blood cells release to tissues. Research compound — IV infusion in studies, no established oral doses 36 PubMed View Profile https://www.bodyhackguide.co/compound/itpp ### SLU-PP-332 Performance Preclinical SLU-PP-332 is the first-generation synthetic pan-agonist of the estrogen-related receptors (ERRα, ERRβ, ERRγ) developed by the laboratory of Thomas Burris at Saint Louis University and reported in a landmark 2023 publication that established ERR pan-agonism as a pharmacologically tractable exercise-mimetic drug mechanism. Research compound — no established human doses. Animal studies: 10-50 mg/kg 8 PubMed View Profile https://www.bodyhackguide.co/compound/slu-pp-332 ### LGD-4033 (Ligandrol) Performance Phase 2 LGD-4033, usually sold as ligandrol, is a nonsteroidal selective androgen receptor modulator that Viking Therapeutics took into clinical development under the code VK5211 (NCT02578095). t½ Long elimination half-life in humans with dose-proportional accumulation over 21 days of daily dosing in healthy young men; the report describes the profile without giving a single value in its summary (PMID: 22459616) Preclinical View Profile https://www.bodyhackguide.co/compound/lgd-4033 ### Ostarine (Enobosarm, MK-2866) Performance Phase 3 Ostarine is the market name for enobosarm, a nonsteroidal selective androgen receptor modulator first developed by GTx Inc under the codes GTx-024, MK-2866 and S-22. t½ Not established from a retrieved human report; in rats the mean elimination half-life of radiolabeled GTx-024 was 0.6 h in males and 16.4 h in females (PMID: 24074268). Human plasma pharmacokinetics were characterized in phase 1 drug-interaction studies (PMID: 27105861) Preclinical View Profile https://www.bodyhackguide.co/compound/ostarine ### PEG-MGF Performance Preclinical PEG-MGF (Pegylated Mechano Growth Factor) is a synthetic, PEGylated form of Mechano Growth Factor (MGF) — an alternatively spliced variant of IGF-1 produced locally in muscle and other tissues in response to mechanical loading or damage. t½ Native MGF: very short (minutes) due to rapid proteolysis. PEG-MGF: PEGylation is intended to extend this substantially (community estimates up to roughly 1 day), but there are no published human pharmacokinetic data to confirm a specific value. 200 mcg Preclinical View Profile https://www.bodyhackguide.co/compound/peg-mgf ### RAD-140 (Testolone) Performance Phase 1 RAD-140, sold as testolone and given the international nonproprietary name vosilasarm, is a nonsteroidal selective androgen receptor modulator developed at Radius Health, whose scientists reported the first-in-human trial (PMID: 34565686), and first described in the medicinal chemistry literature as a compound with an oxadiazole core designed for oral androgen receptor activity with tissue selectivity (PMID: 24900290). t½ Terminal half-life 44.7 hours in humans, measured in a first-in-human phase 1 study in postmenopausal women with metastatic breast cancer (PMID: 34565686) Preclinical View Profile https://www.bodyhackguide.co/compound/rad-140 ## Performance & Recovery (1) Research compounds in the Performance & Recovery family, compiled from peer-reviewed literature and clinical trial registries. ### Vasodrive Amino Blend Performance & Recovery No clinical trials (as a blend); individual components have human RCTs Injectable amino-acid blend formulated for vasodilation and increased blood flow. t½ Not meaningful as a single value for a multi-amino-acid blend. For reference, plasma arginine rises after oral L-citrulline and peaks around 1 hour, and free amino acids are generally cleared over a few hours. Not applicable in micrograms - this blend is dosed in GRAMS. Typical oral ranges: L-citrulline 3-8 g, L-arginine 3-6 g, L-ornithine 2-6 g, L-glutamine ~5 g per day. See the dosing summary for the component breakdown. Preclinical View Profile https://www.bodyhackguide.co/compound/vasodrive-blend ## Pharmaceutical (6) Research compounds in the Pharmaceutical family, compiled from peer-reviewed literature and clinical trial registries. ### Clascoterone Pharmaceutical Preclinical Clascoterone (brand name Winlevi; development codes CB-03-01 and, for the alopecia formulation, Breezula) is a first-in-class topical androgen receptor (AR) antagonist approved by the U.S. 1,188 PubMed View Profile https://www.bodyhackguide.co/compound/clascoterone ### Albuterol (salbutamol) Pharmaceutical FDA Approved Albuterol, called salbutamol outside the United States, is a beta-2 adrenergic agonist and a standard asthma medicine worldwide. t½ Mean terminal half-life 3.8 hours after intravenous administration in 16 healthy adult men, with absolute oral bioavailability of 44 percent and plasma peaks one to three hours after oral administration (PMID: 3653233) Preclinical View Profile https://www.bodyhackguide.co/compound/albuterol ### Finasteride Pharmaceutical Preclinical Finasteride is an orally-active selective type II 5α-reductase inhibitor that blocks the conversion of testosterone to dihydrotestosterone (DHT), the primary androgenic driver of both benign prostatic hyperplasia (BPH) and androgenetic alopecia (male-pattern hair loss). Preclinical View Profile https://www.bodyhackguide.co/compound/finasteride ### Meldonium Pharmaceutical Approved (Latvia) Meldonium, sold as Mildronate, was developed at the Latvian Institute of Organic Synthesis (PMID: 12242052) and is a licensed cardiovascular medicine in Latvia and a number of eastern European and post-Soviet countries. t½ Not a single simple value: in 32 healthy athlete volunteers taking oral meldonium for three weeks, plasma took several days to reach steady state and urinary elimination continued for several months after the last dose, because tissue clearance depends on slow diffusion rather than transport (PMID: 30328291) Preclinical View Profile https://www.bodyhackguide.co/compound/meldonium ### Mirabegron Pharmaceutical FDA Approved Mirabegron is an approved prescription drug, not a research chemical. t½ Terminal half-life about 32 hours in one phase 1 multiple-dose study and about 60 hours in a second, with plasma peaks at three to five hours and steady state within seven days in healthy young and elderly adults (PMID: 23063375) Preclinical View Profile https://www.bodyhackguide.co/compound/mirabegron ### Tropisetron Pharmaceutical Approved (Japan) Tropisetron, coded ICS 205-930 during development and marketed as Navoban, is a serotonin 5-HT3 receptor antagonist approved as an antiemetic in Japan and in many other countries outside the United States, with ATC code A04AA03 (KEGG DRUG D02041, D02130). t½ About 5.7 h after a single 5 mg oral capsule and 5.6 h after 2 mg intravenously in 18 healthy volunteers; oral bioavailability averaged 0.60 with a range of 0.27 to 0.99 and was inversely related to CYP2D6 activity (PMID: 11736884) Preclinical View Profile https://www.bodyhackguide.co/compound/tropisetron ## Polyamine (1) Research compounds in the Polyamine family, compiled from peer-reviewed literature and clinical trial registries. ### Spermidine Polyamine Preclinical Spermidine is a naturally-occurring polyamine essential for cellular growth, division, and differentiation in all living organisms. Preclinical View Profile https://www.bodyhackguide.co/compound/spermidine ## Polyphenol (4) Research compounds in the Polyphenol family, compiled from peer-reviewed literature and clinical trial registries. ### Oleuropein Polyphenol Preclinical Oleuropein is the signature secoiridoid glycoside of Olea europaea — the olive tree — and it is the single most important polyphenol responsible for the cardiovascular, anti-inflammatory, and metabolic benefits long associated with extra-virgin olive oil and with the broader Mediterranean diet. 3,658 PubMed View Profile https://www.bodyhackguide.co/compound/oleuropein ### Hydroxytyrosol Polyphenol Preclinical Hydroxytyrosol (3,4-dihydroxyphenylethanol, abbreviated HT or 3,4-DHPEA) is the smallest of the natural phenolic compounds produced by the olive tree and — pharmacologically — the single most important molecule in the olive polyphenol family. 2,277 PubMed View Profile https://www.bodyhackguide.co/compound/hydroxytyrosol ### Oleocanthal Polyphenol Preclinical Oleocanthal — more precisely (-)-oleocanthal, or p-HPEA-EDA (para-hydroxyphenylethanol elenolic acid dialdehyde) — is the pungent phenolic secoiridoid that gives fresh, high-polyphenol extra-virgin olive oil its characteristic throat-biting, pepper-like sensation when swallowed. 1,156 PubMed View Profile https://www.bodyhackguide.co/compound/oleocanthal ### Hesperidin Polyphenol Preclinical Hesperidin is the signature flavanone glycoside of citrus fruit — specifically the 7-O-rutinoside of hesperetin — and it is the single most abundant flavonoid in the white pith and peel of sweet oranges, lemons, tangerines, and grapefruit. 450 PubMed View Profile https://www.bodyhackguide.co/compound/hesperidin ## Protein (1) Research compounds in the Protein family, compiled from peer-reviewed literature and clinical trial registries. ### Collagen Peptides Protein Preclinical Collagen peptides — also sold as hydrolyzed collagen, collagen hydrolysate, or simply "collagen powder" — are low-molecular-weight protein fragments (typically 2-10 kilodaltons, averaging around 3-6 kDa for most commercial products) produced by enzymatic hydrolysis of animal collagen. 922 PubMed View Profile https://www.bodyhackguide.co/compound/collagen ## Recovery (17) Research compounds in the Recovery family, compiled from peer-reviewed literature and clinical trial registries. ### Glutathione Recovery Clinical Glutathione is the body's most abundant intracellular antioxidant — a three-amino-acid peptide made of glutamate, cysteine, and glycine (Glu-Cys-Gly), present in millimolar concentrations inside every cell of your body. t½ Short: on the order of minutes for intravenous glutathione (intact GSH is cleared rapidly from plasma and cellular uptake of intact GSH is limited). Oral bioavailability is low, so tissue glutathione levels depend mainly on endogenous synthesis from cysteine, glycine, and glutamate rather than on the half-life of administered GSH. 250 mg - 1000 mg daily (oral, IV, or nebulized) 1,971 PubMed View Profile https://www.bodyhackguide.co/compound/glutathione ### Humanin Recovery Preclinical Humanin is a 24-amino-acid peptide (MAPRGFSCLLLLTSEIDLPVKRRA) encoded within the mitochondrial 16S ribosomal RNA gene and translated from a short open reading frame that was not recognized as biologically active until 2001, when Hashimoto and colleagues identified it in a screen for factors that protect neurons from Alzheimer's disease-associated toxicity ([Hashimoto et al., 2001]). t½ Short - on the order of minutes. Wild-type 24-amino-acid humanin is rapidly cleared from plasma (rodent data); the S14G analog (HNG) is more metabolically stable. No human pharmacokinetic data exist. Research compound — no established human doses 257 PubMed View Profile https://www.bodyhackguide.co/compound/humanin ### Thymogen Recovery Approved in Russia / not Western-validated Thymogen (also transliterated Timogen or ╨ó╨╕╨╝╨╛╨│╨╡╨╜) is a synthetic dipeptide — glutamyl-tryptophan (Glu-Trp, or EW) — developed by the St Petersburg Institute of Bioregulation and Gerontology under Professor Vladimir Khavinson. t½ short; not well characterized 50-100 mcg intranasal per nostril 1-2x/day, or 100 mcg SC once daily; 10-day courses, 2-4x/year 91 PubMed View Profile https://www.bodyhackguide.co/compound/thymogen ### Vilon Recovery Preclinical Vilon is the simplest member of Vladimir Khavinson's short-peptide bioregulator catalog — a dipeptide of lysine and glutamic acid (H-Lys-Glu-OH, abbreviated KE). t½ Not established in humans; as a dipeptide (Lys-Glu) it is expected to be cleared from plasma within minutes, with proposed effects attributed to transient gene-expression modulation rather than sustained blood levels. 20 mg oral capsule (~2-4 mg Lys-Glu peptide), 1-2 capsules daily for 10 consecutive days per cycle 74 PubMed View Profile https://www.bodyhackguide.co/compound/vilon ### ARA-290 Recovery Phase 2 ARA-290, also known as Cibinetide or pHBSP (Helix B Surface Peptide), is an 11-amino-acid peptide — QEQLERALNSS — designed to mimic a specific region of the tissue-protective surface of erythropoietin (EPO) without activating the classical hematopoietic EPO receptor that drives red blood cell production. t½ ~2 minutes (plasma half-life; downstream tissue-protective effects persist hours to days) 1 mg - 4 mg subcutaneous daily 52 PubMed View Profile https://www.bodyhackguide.co/compound/ara-290 ### KPV Recovery Preclinical KPV is a three-amino-acid peptide — Lysine-Proline-Valine — that makes up the C-terminal tail of alpha-MSH (alpha-melanocyte-stimulating hormone). t½ ~15–30 minutes (short-lived but downstream anti-inflammatory effects persist) 500 mcg-2 mg per dose (standard); up to 5 mg daily in advanced protocols 33 PubMed View Profile https://www.bodyhackguide.co/compound/kpv ## Reproductive Hormone (1) ### Kisspeptin-10 Reproductive Hormone Phase 1-2 (fertility applications) Kisspeptin-10 is a 10-amino-acid C-terminal fragment of the KISS1 gene product. t½ Very short: approximately 4 minutes in human plasma due to rapid enzymatic degradation. Note: the ~28-minute half-life frequently cited for 'kisspeptin' actually belongs to the longer kisspeptin-54, not kisspeptin-10. Because kisspeptin-10 clears within minutes, a single injection produces only a brief gonadotropin (LH/FSH) pulse, and sustained stimulation of the reproductive axis in research required continuous IV infusion or repeated pulsatile dosing rather than once- or twice-weekly single boluses. 50-200 mcg single bolus; or 100 mcg every 90 min for pulsatile protocols 998 PubMed View Profile https://www.bodyhackguide.co/compound/kisspeptin ## Senolytics (1) Research compounds in the Senolytics family, compiled from peer-reviewed literature and clinical trial registries. ### Dasatinib Senolytics Preclinical Dasatinib (SPRYCEL) is a second-generation oral tyrosine kinase inhibitor (TKI) with FDA approvals for chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Preclinical View Profile https://www.bodyhackguide.co/compound/dasatinib ## Skin & Hair (6) Research compounds in the Skin & Hair family, compiled from peer-reviewed literature and clinical trial registries. ### Acetyl Hexapeptide-8 Skin & Hair Marketed topical cosmetic ingredient (INCI: Acetyl Hexapeptide-8 / Argireline). Supported by small human anti-wrinkle studies, including one randomized, placebo-controlled trial; no systemic or injectable clinical development. Not an FDA-approved drug. Acetyl Hexapeptide-8 (INCI: Acetyl Hexapeptide-3 in older nomenclature, commercially known as Argireline) is a synthetic hexapeptide designed as a competitive inhibitor of the SNARE complex at the neuromuscular junction. t½ Short (topical application, no systemic absorption at cosmetic doses) Preclinical View Profile https://www.bodyhackguide.co/compound/acetyl-hexapeptide-8 ### AHK-Cu Skin & Hair Preclinical AHK-Cu (Ala-His-Lys-Copper) is a copper chelating tripeptide related to but distinct from GHK-Cu (Gly-His-Lys-Copper). t½ Unknown (topical half-life, follicular retention not well characterized) Preclinical View Profile https://www.bodyhackguide.co/compound/ahk-cu ### Melanotan 2 Skin & Hair Discontinued (early clinical) A synthetic melanocortin receptor agonist studied for skin tanning, sexual function, and appetite suppression.. t½ ~1–2 hours 100-1,000 mcg per injection Preclinical View Profile https://www.bodyhackguide.co/compound/melanotan-2 ### Minoxidil Skin & Hair FDA-Approved Minoxidil is an FDA-approved treatment for pattern hair loss. t½ Oral minoxidil plasma half-life is approximately 3-4 hours; the hair-growth (pharmacodynamic) effect is independent of plasma level and depends on ongoing daily use. Oral low-dose minoxidil (off-label): 625-5000 mcg/day (0.625-5 mg). Topical minoxidil is dosed by concentration (2% or 5%), not by mcg -- roughly 10-20 mg of minoxidil is delivered per topical application, with only ~1.4% absorbed systemically. Preclinical View Profile https://www.bodyhackguide.co/compound/minoxidil ### PDRN Skin & Hair Phase 4 PDRN (Polydeoxyribonucleotide) is a biotechnological compound derived from salmon sperm DNA (Oncorhynchus mykiss) through extraction, purification, and fractionation. t½ Short (oligonucleotides degraded rapidly; tissue effects persist longer) Preclinical View Profile https://www.bodyhackguide.co/compound/pdrn ### Snap-8 Skin & Hair Preclinical Snap-8 (INCI: Acetyl Glutamyl Heptapeptide-1) is a synthetic octapeptide designed as an analog of the N-terminal fragment of synaptosomal-associated protein of 25 kDa (SNAP-25), which is the molecular target of botulinum toxin A (Botox). t½ Not characterized (topical peptide) Preclinical View Profile https://www.bodyhackguide.co/compound/snap-8 ## Skin / Cosmetic (1) Research compounds in the Skin / Cosmetic family, compiled from peer-reviewed literature and clinical trial registries. ### Melanotan II Skin / Cosmetic Duplicate entry - see Melanotan II This is a duplicate/alias entry. Preclinical View Profile https://www.bodyhackguide.co/compound/mt-ii ## Skin, Hair & Aesthetics (3) Research compounds in the Skin, Hair & Aesthetics family, compiled from peer-reviewed literature and clinical trial registries. ### PT-141 (Bremelanotide) Skin, Hair & Aesthetics FDA Approved PT-141 (bremelanotide) is a cyclic 7-amino-acid synthetic melanocortin receptor agonist that acts centrally in the brain — not peripherally on genital tissue — to improve sexual desire, arousal, and responsiveness. t½ ~2.7 hours 500–2,000 mcg (0.5–2 mg) per dose 40 PubMed View Profile https://www.bodyhackguide.co/compound/pt-141 ### Melanotan II Skin, Hair & Aesthetics Preclinical Melanotan-II (MT-II) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) engineered in the late 1980s by researchers at the University of Arizona, most prominently Mac Hadley and Victor Hruby, who were searching for a way to stimulate skin pigmentation pharmacologically as a potential skin-cancer prophylactic. t½ Approximately 30-60 minutes (subcutaneous; limited published human pharmacokinetic data). Peak plasma levels occur ~1-2 hours after injection, and subjective effects typically persist 4-8 hours. 17 PubMed View Profile https://www.bodyhackguide.co/compound/melanotan-ii ### GHK-Cu Skin, Hair & Aesthetics N/A for injectable (no Phase 1/2/3 injectable trials). One Phase 2 TOPICAL gel wound-healing trial is recruiting (NCT07437586); topical cosmetic use otherwise has small human studies with no drug-phase designation. GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a molecule Pickart and Thaler first pulled out of human plasma in 1973. t½ ~30-60 min (plasma; approximate legacy figure, no robust modern human PK study) 200-500 mcg SC daily (community/RUO; no clinically established injectable dose) 6 PubMed View Profile https://www.bodyhackguide.co/compound/ghk-cu ## Sleep (1) Research compounds in the Sleep family, compiled from peer-reviewed literature and clinical trial registries. ### Dream Spray Sleep Duplicate entry - see DSIP (Delta Sleep-Inducing Peptide) This is a duplicate/alias entry. Preclinical View Profile https://www.bodyhackguide.co/compound/dream-spray ## Sleep & Circadian (2) Research compounds in the Sleep & Circadian family, compiled from peer-reviewed literature and clinical trial registries. ### Melatonin Sleep & Circadian Preclinical Melatonin (chemical name N-acetyl-5-methoxytryptamine) is an endogenous neurohormone synthesized primarily by the pineal gland and, in smaller quantities, by the retina, gut, skin, bone marrow, lymphocytes, and mitochondria across most tissues. 12,556 PubMed View Profile https://www.bodyhackguide.co/compound/melatonin ### Sleep Research Blend Sleep & Circadian No trials of the blend; component-level preclinical and limited early-human research only (RUO) Sleep Research Blend is a proprietary, multi-component research preparation that BHG Labs lists as BHG-SR Research Blend, an atomized (intranasal) solution cataloged for laboratory sleep-architecture and circadian research. Composition-dependent, read the COA. Community intranasal archetype: ~100-300 mcg DSIP-equivalent and ~50-100 mcg epitalon-equivalent per evening administration. Preclinical View Profile https://www.bodyhackguide.co/compound/sleep-research-blend ## Stilbene Polyphenol (1) Research compounds in the Stilbene Polyphenol family, compiled from peer-reviewed literature and clinical trial registries. ### Pterostilbene Stilbene Polyphenol Preclinical Pterostilbene is a naturally-occurring stilbene polyphenol (trans-3,5-dimethoxy-4'-hydroxystilbene) that is structurally and functionally related to resveratrol but has substantially superior pharmacokinetic properties. Preclinical View Profile https://www.bodyhackguide.co/compound/pterostilbene ## Supplement (1) Research compounds in the Supplement family, compiled from peer-reviewed literature and clinical trial registries. ### Probiotics Supplement Preclinical Probiotics — defined by the joint FAO/WHO 2001 consensus as "live microorganisms which, when administered in adequate amounts, confer a health benefit on the host" — are the most widely sold and most widely misunderstood category of dietary supplement. 24,468 PubMed View Profile https://www.bodyhackguide.co/compound/probiotics ## Supplies (1) Research compounds in the Supplies family, compiled from peer-reviewed literature and clinical trial registries. ### BAC Water Supplies Not applicable - established pharmaceutical diluent (reconstitution supply), not a research-stage compound. Bacteriostatic water (BAC water) is Sterile Water for Injection preserved with 0.9% benzyl alcohol, used to reconstitute lyophilized (freeze-dried) research peptides into an injectable solution. t½ Not applicable - reconstitution diluent, not a dosed compound. N/A - BAC water is a reconstitution diluent, not a dosed compound. Typical amount mixed per peptide vial is ~1-3 mL, chosen by concentration math rather than by dose. Preclinical View Profile https://www.bodyhackguide.co/compound/bac-water ## Tanning Peptide (1) ### Melanotan-1 Tanning Peptide FDA-approved for EPP (Scenesse, 2019) Melanotan-1 (afamelanotide, brand name Scenesse) is a synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH). t½ ~30 minutes serum (subcutaneous absorption is the rate-limiter for clinical use) 500-1000 mcg loading; 500 mcg maintenance 4 PubMed View Profile https://www.bodyhackguide.co/compound/melanotan-1 ## Vitamin (9) Research compounds in the Vitamin family, compiled from peer-reviewed literature and clinical trial registries. ### Vitamin E Vitamin Preclinical Vitamin E is the collective name for eight naturally occurring fat-soluble molecules — four tocopherols (α, β, γ, δ) and four tocotrienols (α, β, γ, δ) — sharing a chromanol head group and a 16-carbon isoprenoid side chain. 6,280 PubMed View Profile https://www.bodyhackguide.co/compound/vitamin-e ### Vitamin A Vitamin Preclinical Vitamin A is the fat-soluble vitamin family encompassing three interconvertible oxidation states — retinol (the alcohol form, the primary transport and storage species), retinal (the aldehyde, the vision-critical form), and retinoic acid (the carboxylic acid, the nuclear receptor ligand) — along with the provitamin A carotenoids, chiefly β-carotene, that plants use to provide animals a dietary precursor. 5,362 PubMed View Profile https://www.bodyhackguide.co/compound/vitamin-a ### Pantothenic Acid Vitamin Preclinical Pantothenic acid is the water-soluble B-complex vitamin — officially vitamin B5 — that every aerobic cell on the planet converts into Coenzyme A (CoA) and the 4'-phosphopantetheine prosthetic arm of acyl carrier protein (ACP). 4,023 PubMed View Profile https://www.bodyhackguide.co/compound/pantothenic-acid ### Biotin Vitamin Preclinical Biotin (vitamin B7, also called vitamin H from the German Haut for "skin" and historically named coenzyme R, factor W, factor R, factor X, vitamin Bw, or Bios II in various discovery-era nomenclatures) is a water-soluble vitamin that serves as the covalently-attached prosthetic group for five carboxylase enzymes in human metabolism: pyruvate carboxylase, acetyl-CoA carboxylase 1, acetyl-CoA carboxylase 2, propionyl-CoA carboxylase, and 3-methylcrotonyl-CoA carboxylase. Preclinical View Profile https://www.bodyhackguide.co/compound/biotin ### Folate Vitamin Preclinical Folate is the generic term for a family of water-soluble B-vitamin compounds that share a pteridine-para-aminobenzoic-acid-glutamate backbone and serve as single-carbon transfer cofactors in nucleotide synthesis, amino acid metabolism, and methylation. Preclinical View Profile https://www.bodyhackguide.co/compound/folate ### Niacin Vitamin Preclinical Niacin (vitamin B3) is an umbrella name for a family of closely related vitamers that share the same ultimate metabolic fate — conversion to the pyridine nucleotide coenzymes NAD+ (nicotinamide adenine dinucleotide) and NADP+ (nicotinamide adenine dinucleotide phosphate) that serve as the central electron carriers of intermediary metabolism and as substrates for an expanding family of NAD-consuming enzymes (sirtuins, PARPs, CD38, SARM1). Preclinical View Profile https://www.bodyhackguide.co/compound/niacin ## Weight Loss (10) Research compounds in the Weight Loss family, compiled from peer-reviewed literature and clinical trial registries. ### L-Carnitine Weight Loss Preclinical L-Carnitine is a naturally occurring quaternary ammonium compound synthesized in the body from the amino acids lysine and methionine, with essential cofactor roles in fatty acid metabolism, energy production, and cellular health. 500 mg - 2000 mg daily (oral or injection) 4,002 PubMed View Profile https://www.bodyhackguide.co/compound/l-carnitine ### BAM15 Weight Loss Preclinical BAM15 is a small-molecule mitochondrial protonophore uncoupler that was first described in 2014 as a tool compound for dissipating proton motive force selectively across the inner mitochondrial membrane without collapsing the plasma membrane electrochemical gradient ([Kenwood et al., 2014]). Research compound — no established human doses. Animal studies use 10-100 mg/kg 58 PubMed View Profile https://www.bodyhackguide.co/compound/bam15 ### Tesofensine Weight Loss Preclinical Tesofensine (NS2330) is an orally-administered small-molecule triple monoamine reuptake inhibitor — it blocks the reuptake of noradrenaline, dopamine, and serotonin, placing it in the same broad pharmacologic class as sibutramine (withdrawn 2010 for cardiovascular risk) but with a different receptor-affinity profile and markedly longer half-life. 0.25 mg - 1 mg daily (oral) 55 PubMed View Profile https://www.bodyhackguide.co/compound/tesofensine ### Mazdutide Weight Loss Approved (China, NMPA 2025); investigational in US/EU Mazdutide (also known as IBI362, Lilly compound LY3305677) is a dual glucagon-like peptide-1 (GLP-1) and glucagon receptor agonist originally discovered by Eli Lilly and exclusively licensed to Innovent Biologics in 2019 for development and commercialization in Mainland China, Hong Kong, Macau, and Taiwan. Research doses — clinical trial protocols vary 39 PubMed View Profile https://www.bodyhackguide.co/compound/mazdutide ### 5-Amino-1MQ Weight Loss Preclinical 5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide to form 1-methylnicotinamide (1-MNA) and S-adenosyl-L-homocysteine (SAH). t½ ~6–12 hours (oral) 50 mg - 150 mg daily (oral or injection) Preclinical View Profile https://www.bodyhackguide.co/compound/5-amino-1mq ### Eloralintide (LY3841136) Weight Loss Phase 3 Eloralintide is an amylin analog developed by Eli Lilly and Company for weight management, given as a once-weekly subcutaneous injection. t½ Terminal geometric mean half-life 310 to 366 hours, that is 12.9 to 15.3 days, across the doses tested in the phase 1 single-ascending-dose study in humans (PMID: 41109426) Preclinical View Profile https://www.bodyhackguide.co/compound/eloralintide ## herb (4) Research compounds in the herb family, compiled from peer-reviewed literature and clinical trial registries. ### Gotu Kola herb Preclinical Gotu Kola (Centella asiatica) is one of the oldest and most extensively studied rasayana herbs in Ayurveda — a classical medhya (mind-nourishing) plant that has been used for more than 3,000 years across India, Sri Lanka, China, Indonesia, Thailand, Malaysia, and Madagascar for three main purposes: sharpening cognition and memory, healing wounds and damaged connective tissue, and restoring venous and microvascular circulation. Preclinical View Profile https://www.bodyhackguide.co/compound/gotu-kola ### Hawthorn herb Preclinical Hawthorn (Crataegus species — principally Crataegus monogyna, C. Preclinical View Profile https://www.bodyhackguide.co/compound/hawthorn ### Horny Goat Weed herb Preclinical Horny Goat Weed — also called Epimedium, Yin Yang Huo (µ╖½τ╛èΦù┐) in Traditional Chinese Medicine, and barrenwort or bishop's hat in Western botanical nomenclature — is a genus of flowering plants in the Berberidaceae family, with roughly 60 species concentrated in China, Korea, and Japan, of which Epimedium sagittatum, E. Preclinical View Profile https://www.bodyhackguide.co/compound/horny-goat-weed ### Mucuna Pruriens herb Preclinical Mucuna pruriens — known as velvet bean in English, Kapikacchu (αñòαñ¬αñ┐αñòαñÜαÑìαñ¢αÑé) or Atmagupta in Sanskrit, Kauchni or Kaunch in Hindi, and cowitch or cowhage in older Western materia medica — is one of the most pharmacologically unusual legumes on earth and one of the very few medicinal plants whose primary active constituent is a well-characterized pharmaceutical drug rather than a complex phytochemical mixture. Preclinical View Profile https://www.bodyhackguide.co/compound/mucuna-pruriens ## Browse Full Database Filter by category, research phase, and research field, or use the search bar at the top of the page. Sort Category Phase Field 273 compounds in database ### Probiotics Supplement Preclinical ### Melatonin Sleep & Circadian Preclinical ### Panax ginseng Adaptogen Preclinical ### Vitamin E Vitamin Preclinical ### Silymarin ### Beta-Sitosterol Herbal Preclinical ### Vitamin A Vitamin Preclinical ### DHEA Hormone Preclinical ### Astaxanthin Carotenoid Preclinical ### Caffeine Nootropic Preclinical ### Pantothenic Acid Vitamin Preclinical ### L-Carnitine Weight Loss Preclinical ### Inositol Nootropic Preclinical ### Oleuropein Polyphenol Preclinical ### Semaglutide Metabolic & Weight Loss FDA Approved ### L-Tryptophan Nootropic Preclinical ### NAD+ Longevity Phase II ### LL-37 Immune & Inflammation Phase 2 ### Methylene Blue Nootropics Preclinical 0.5 mg - 4 mg/kg daily (oral) ### Hydroxytyrosol Polyphenol Preclinical ### Piperine Herbal Preclinical ### Lutein Carotenoid Preclinical ### Glutathione Recovery Clinical ### Chromium Mineral Preclinical ### Manganese Mineral Preclinical ### PQQ (Pyrroloquinoline Quinone) Cofactor Preclinical ### Dong Quai Adaptogen Preclinical ### Calcium Mineral Preclinical ### L-Theanine Nootropics FDA Approved ### Clascoterone Pharmaceutical Preclinical ### Oleocanthal Polyphenol Preclinical ### Fadogia Agrestis Adaptogen Preclinical ### TB-500 Injury, Repair & Recovery Phase 2 ### Kisspeptin-10 ### Reishi Adaptogen Preclinical ### Molybdenum Mineral Preclinical ### Collagen Peptides Protein Preclinical ### Uridine Monophosphate (UMP) Nootropics Preclinical ### Grape Seed Extract Herbal Preclinical ### Ashwagandha Adaptogen Preclinical ### Schisandra Adaptogen Preclinical ### Cordyceps Adaptogen Preclinical Cordyceps is a genus of parasitic fungi (order Hypocreales, family Cordycipitaceae) historically prized in traditional Tibetan, Chinese, and Bhutanese medicine for their purported abilities to restore vitality, improve athletic performance, support respiratory and kidney function, and promote longevity. 776 PubMed View Profile https://www.bodyhackguide.co/compound/cordyceps ### Saw Palmetto Herbal Preclinical ### Maitake Herbal Preclinical ### Thymosin Alpha-1 (TA1) Immune & Inflammation FDA Approved ### Rhodiola rosea Adaptogen Preclinical Rhodiola rosea is a succulent perennial plant that grows in cold, high-altitude regions of the Arctic, Siberia, Scandinavia, Iceland, the Alps, the Pyrenees, and the Carpathian Mountains. 695 PubMed View Profile https://www.bodyhackguide.co/compound/rhodiola-rosea ### Tirzepatide Metabolic & Weight Loss FDA Approved ### Oxytocin ### Kisspeptin-10 Hormones & Endocrine (Non-GH) Phase 2 ### Tribulus Terrestris Adaptogen Preclinical Tribulus terrestris (scientific name Tribulus terrestris L.; also called puncture vine, caltrop, goat's head, devil's thorn, bindii in Australia, gokshura or gokhru in Sanskrit and Ayurveda, and ci ji li (σê║ΦÆ║Φù£) in Traditional Chinese Medicine) is a low-growing annual herb of the family Zygophyllaceae with a remarkably cosmopolitan distribution — native to warm temperate and tropical regions of Europe, Asia, Africa, and Australia, and introduced as an invasive weed across the Americas. 581 PubMed View Profile https://www.bodyhackguide.co/compound/tribulus-terrestris ### Lion's Mane Mushroom Nootropics Phase 2 ### DSIP (Delta Sleep-Inducing Peptide) ### Astragalus (Huang Qi) Adaptogen Preclinical Astragalus (scientific name Astragalus membranaceus, also classified as Astragalus mongholicus or Astragalus propinquus; called Huang Qi / Θ╗äΦè¬ in Mandarin Chinese — literally "yellow leader" referring to the yellow interior of the root; known in Western herbalism as milk vetch root or simply astragalus root; Radix Astragali in pharmacopeial Latin) is a perennial legume in the Fabaceae family (pea family), native to northern and northeastern China, Mongolia, Korea, and Siberia. 497 PubMed View Profile https://www.bodyhackguide.co/compound/astragalus ### Gonadorelin ### Hesperidin Polyphenol Preclinical ### Follistatin-344 ### Bacopa monnieri Nootropic Adaptogen Preclinical ### Boron Mineral Preclinical ### Tulsi (Holy Basil) Adaptogen Preclinical Tulsi (scientific name Ocimum tenuiflorum, formerly classified as Ocimum sanctum; called tulasi in Sanskrit and most Indian languages, holy basil or sacred basil in Western herbalism, and kala tulsi or manjari for specific varieties) is a perennial aromatic herb in the Lamiaceae family (mint family), native to the Indian subcontinent but now cultivated throughout tropical and subtropical regions worldwide. 292 PubMed View Profile https://www.bodyhackguide.co/compound/tulsi ### Eleuthero Adaptogen Preclinical Eleuthero (scientific name Eleutherococcus senticosus, formerly classified as Acanthopanax senticosus; called ci wu jia in Chinese, siberian ginseng in Western herbalism — though this common name is problematic and technically inaccurate as eleuthero is NOT in the Panax genus of true ginsengs — devil's shrub or touch-me-not in some English sources, and russian root reflecting its extensive Russian use) is a deciduous shrub in the Araliaceae family (ivy family), growing 2-3 meters tall with spiny stems, native to the cold temperate forests of the Russian Far East (Primorsky and Khabarovsk regions, Amur and Ussuri river basins), Northeast China, Korea, and Hokkaido Japan. 277 PubMed View Profile https://www.bodyhackguide.co/compound/eleuthero ### Humanin Recovery Preclinical ### American Ginseng Adaptogen Preclinical American ginseng (Panax quinquefolius) is the North American cousin of Asian ginseng (Panax ginseng), native to the cool, shaded hardwood forests of the eastern United States and southeastern Canada. 252 PubMed View Profile https://www.bodyhackguide.co/compound/american-ginseng ### BPC-157 Injury, Repair & Recovery Preclinical ### GHRP-2 Growth Hormone / IGF-1 Axis Phase 2 ### Magnesium L-Threonate Nootropic Preclinical ### Semax ### Boswellia Herbal Preclinical ### Sermorelin ### MOTS-c Longevity & Cellular Health Preclinical ### GHRP-6 Growth Hormone / IGF-1 Axis Phase 2 ### Retatrutide Metabolic & Weight Loss Phase 3 ### Tongkat Ali Adaptogen Preclinical Tongkat Ali (scientific name Eurycoma longifolia; also called Longjack, Malaysian ginseng, pasak bumi in Indonesian/Malay, tung saw in Thai, and literally "Ali's walking stick" in Malay — a reference to the remarkably long, straight, single taproot that can grow 10-15 feet deep into Southeast Asian rainforest soil) is a slender understory tree of the family Simaroubaceae native to the tropical rainforests of peninsular Malaysia, Indonesia, Thailand, Vietnam, Myanmar, Laos, and the Philippines. 107 PubMed View Profile https://www.bodyhackguide.co/compound/tongkat-ali ### Noopept Nootropics Russia Approved ### P-21 Nootropics Preclinical P-21 (also written P021, or Peptide 021) is a synthetic peptidergic compound derived from the neurotrophic region of ciliary neurotrophic factor (CNTF), designed to activate neurogenic and BDNF-producing pathways in the adult brain without triggering the activation of the CNTF receptor that causes the undesirable side effects (cachexia, muscle wasting) that limited CNTF itself as a therapeutic. 500-2000 mcg (0.5-2 mg) daily, most commonly 500-1000 mcg (community/self-experimentation range; no clinical validation) 98 PubMed View Profile https://www.bodyhackguide.co/compound/p-21 ### Enclomiphene Hormone Support Phase III ### Thymogen ### Selank Nootropics Approved (Russia, as anxiolytic and nootropic medication) Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro, 750 Da molecular weight) developed in the 1990s at the Institute of Molecular Genetics of the Russian Academy of Sciences as a synthetic analog of tuftsin — an immunomodulatory tetrapeptide (Thr-Lys-Pro-Arg) that is naturally cleaved from the Fc region of immunoglobulin G. t½ ~2-3 minutes plasma half-life (functional anxiolytic and nootropic effects persist 12-24 hours due to gene expression and neurotransmitter modulation) 250-750 mcg intranasal daily (0.15% solution: 2-3 drops per nostril 2-3x daily); typical course is 14-21 days 88 PubMed View Profile https://www.bodyhackguide.co/compound/selank ### Vitamin D Foundational Preclinical ### Cerebrolysin Nootropic Peptide Clinical ### Theacrine Nootropics Dietary Supplement (Food Ingredient) Theacrine (1,3,7,9-tetramethyluric acid) is a purine alkaloid structurally related to caffeine, found naturally in Camellia assamica var. t½ 16-20 hours (plasma); Tmax 60-90 minutes 80 PubMed View Profile https://www.bodyhackguide.co/compound/theacrine ### Vilon Recovery Preclinical ### Maca (Lepidium meyenii) Adaptogen Preclinical Maca (scientific name Lepidium meyenii; called maca in Spanish and Quechua; historically ayak chichira or ayuk willku in pre-Columbian Andean languages; marketed as Peruvian Ginseng in some Western commerce — though it is botanically unrelated to true ginseng from the Araliaceae family) is an annual herbaceous plant in the Brassicaceae (mustard/cabbage) family. 63 PubMed View Profile https://www.bodyhackguide.co/compound/maca ### Oleamide Nootropic Lipid Preclinical ### Survodutide ### BAM15 Weight Loss Preclinical ### CDP-Choline Nootropic Phase 4 ### Tesofensine Weight Loss Preclinical 0.25 mg - 1 mg daily (oral) ### Pygeum Herbal Preclinical Pygeum (Prunus africana, formerly classified as Pygeum africanum) is a lipophilic bark extract derived from the African cherry tree — a large, slow-growing evergreen hardwood species native to the mountainous forests of sub-Saharan Africa, from Cameroon and Kenya through Uganda, Tanzania, Ethiopia, Madagascar, and south to South Africa. 54 PubMed View Profile https://www.bodyhackguide.co/compound/pygeum ### ARA-290 Recovery Phase 2 ### Vitamin C Foundational Preclinical ### Epitalon Bioregulator Peptide Preclinical ### Cagrilintide Metabolic & Weight Loss Phase 3 t½ ~159 hours (approximately 7 days) ### MK-677 (Ibutamoren) Growth Hormone / IGF-1 Axis Phase 2 ### Papain Enzyme Preclinical ### Sulbutiamine Nootropics Phase 4 Sulbutiamine (chemical name: isobutyryl thiamine disulfide; trade names include Arcalion, Enerion, Bisibutiamine) is a lipophilic synthetic derivative of vitamin B1 (thiamine), developed in Japan in the 1960s by Sankyo Company chemists who were seeking thiamine analogs with enhanced absorption and tissue penetration — particularly brain penetration. 41 PubMed View Profile https://www.bodyhackguide.co/compound/sulbutiamine ### IGF-1 LR3 Growth Hormone / IGF-1 Axis Phase 2 ### PT-141 (Bremelanotide) Skin, Hair & Aesthetics FDA Approved ### Mazdutide ### ITPP Performance Preclinical ### Bromantane Nootropics Russia Approved Bromantane is an atypical psychostimulant and anxiolytic developed in the 1980s at the Zakusov Institute of Pharmacology of the Russian Academy of Medical Sciences, originally created as an adaptogen for Soviet military and elite athletic use and later approved in Russia for the treatment of neurasthenic and asthenic disorders under the trade name Ladasten. 34 PubMed View Profile https://www.bodyhackguide.co/compound/bromantane ### KPV Recovery Preclinical ### IGF-1 Des(1-3) t½ ~20-30 minutes serum 20-100 mcg ### CJC-1295 (Mod GRF 1-29) Growth Hormone / IGF-1 Axis Preclinical ### Vesugen Recovery Preclinical Vesugen is a short synthetic peptide developed within Vladimir Khavinson's laboratory at the Saint Petersburg Institute of Bioregulation and Gerontology and marketed in Russia as an oral capsule for vascular and endothelial system support. t½ Not established in humans. As a short tripeptide, KED is expected to be rapidly hydrolyzed in plasma, with an anticipated half-life on the order of minutes; no formal pharmacokinetic study of Vesugen has been published. 20 mg oral capsule 1-2 daily for 10-day cycles (60-90 day washout) 27 PubMed View Profile https://www.bodyhackguide.co/compound/vesugen ### Piracetam Nootropics Preclinical Piracetam is the prototypical nootropic — the compound that inaugurated an entire class of cognitive enhancement drugs and gave the category its name. 23 PubMed View Profile https://www.bodyhackguide.co/compound/piracetam ### Pinealon Nootropics Preclinical Pinealon is a synthetic tripeptide — glutamyl-aspartyl-arginine (Glu-Asp-Arg, or EDR) — developed by the St Petersburg Institute of Bioregulation and Gerontology (IBG) under the leadership of Professor Vladimir Khavinson, the dominant figure in what is collectively known as the "Russian short-peptide bioregulator" school of research. t½ Not formally characterized in humans. Short regulatory peptides of this class are cleared from plasma within minutes; the Khavinson framework proposes durable downstream gene-expression effects that outlast the brief dosing window, which is the stated rationale for pulsed cycling rather than continuous dosing. Subcutaneous (primary route): 2-10 mg/day, typically 3-5 mg, in pulsed 10-20 day cycles, 2-4 cycles/year. Intranasal: 150-800 mcg per nostril daily. Research use only; oral dosing is not recommended because the peptide is largely degraded by GI proteases. 21 PubMed View Profile https://www.bodyhackguide.co/compound/pinealon ### MGF (Mechano Growth Factor) ### Selenium Foundational Preclinical ### Ovagen Liver/Digestive Preclinical ### Cortexin ### Livagen Recovery Preclinical Livagen is a short synthetic peptide developed in Russia by Vladimir Khavinson and his collaborators at the St. 20 mg oral/sublingual capsule once daily for 10 consecutive days per cycle (or 2-5 mg subcutaneous daily using synthetic peptide); 60-90 day washout between cycles 17 PubMed View Profile https://www.bodyhackguide.co/compound/livagen ### Melanotan II Skin, Hair & Aesthetics Preclinical ### Hexarelin Growth Hormone / IGF-1 Axis Phase 2 Hexarelin (also called examorelin) is a potent synthetic hexapeptide growth hormone secretagogue with the sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2. t½ ~55 minutes (IV, per Imbimbo 1994) 100–200 mcg per injection 14 PubMed View Profile https://www.bodyhackguide.co/compound/hexarelin ### Omega-3 Fatty Acids Foundational Preclinical ### B7-33 Other Preclinical ### Ipamorelin Growth Hormone / IGF-1 Axis Preclinical Ipamorelin is a selective pentapeptide ghrelin receptor (GHS-R1a) agonist — one of the most studied growth hormone secretagogues (GHS) in the biohacking community and the modern companion to CJC-1295 / MOD-GRF 1-29. t½ ~2 hours (plasma) 100-300 mcg subcutaneous 1-3x daily (most commonly 200-300 mcg pre-bedtime); often combined with CJC-1295 without DAC at 100-300 mcg 11 PubMed View Profile https://www.bodyhackguide.co/compound/ipamorelin ### RU-58841 Other Preclinical ### Alpha-GPC Nootropic Phase 4 ### Aminotadalafil Other Preclinical 2.5 mg - 20 mg (oral) ### Cardiogen Recovery Preclinical Cardiogen is a short synthetic peptide developed in Russia by Vladimir Khavinson and his collaborators at the St. t½ Not characterized in humans. As a short linear tetrapeptide (Ala-Glu-Asp-Arg), Cardiogen is expected to undergo rapid enzymatic hydrolysis to its constituent amino acids; no validated modern pharmacokinetic half-life has been published. 20 mg oral once daily x10 days, or 2-5 mg SC daily x10 days; 60-90 day washout 9 PubMed View Profile https://www.bodyhackguide.co/compound/cardiogen ### FOXO4-DRI Recovery Preclinical FOXO4-DRI is a synthetic 34-amino-acid D-retro-inverso peptide designed to disrupt the interaction between the FOXO4 transcription factor and p53, with the specific goal of inducing apoptosis selectively in senescent cells. t½ Not established in humans; no published human pharmacokinetic data. The D-retro-inverso construction confers resistance to human proteases, which in preclinical models extends the in vivo half-life from minutes (typical for comparable L-amino-acid peptides) to hours ([Baar et al., 2017](https://pubmed.ncbi.nlm.nih.gov/28340339/)). No validated human dose. Self-report: 2-15 mg SC per dose (typically 5 mg), pulsed 3-7 days every 2-6 months; no human PK data. The 5 mg/kg figure seen in some sources is a mouse research dose (Baar 2017), not a human dose. 8 PubMed View Profile https://www.bodyhackguide.co/compound/foxo4-dri ### L-Tyrosine Nootropics Preclinical L-Tyrosine is a non-essential aromatic amino acid and the direct biosynthetic precursor to the catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine. 8 PubMed View Profile https://www.bodyhackguide.co/compound/l-tyrosine ### SLU-PP-332 Performance Preclinical ### Tesamorelin Tesamorelin is a stabilized synthetic analog of human growth hormone-releasing hormone (GHRH) — specifically the full 44-amino-acid GHRH sequence with a single N-terminal trans-3-hexenoyl fatty-acid modification. t½ 30-50 minutes (plasma) 1,000–2,000 mcg (1–2 mg) daily 8 PubMed View Profile https://www.bodyhackguide.co/compound/tesamorelin ### Bronchogen Recovery Preclinical Bronchogen is a short synthetic peptide developed in Russia by Vladimir Khavinson and his collaborators at the St. t½ Not established (no published human pharmacokinetic data; rapid enzymatic hydrolysis within minutes is expected for a tetrapeptide of this class) 20 mg oral capsule once daily, 10-day cycles 7 PubMed View Profile https://www.bodyhackguide.co/compound/bronchogen ### Urolithin A Mitochondrial Support Preclinical ### 9-Me-BC (9-Methyl-β-carboline) Nootropics Preclinical 9-Methyl--carboline (9-Me-BC) is a synthetic -carboline alkaloid that has drawn nootropic-community interest for a preclinical property that is genuinely unusual among -carbolines: in rodent and cell-culture studies it appears to stimulate the dopaminergic phenotype - raising tyrosine hydroxylase, the number of differentiated dopamine neurons and dopamine content - while also showing neuroprotective, neurorestorative and anti-inflammatory effects, plus in-vitro MAO-A/MAO-B inhibition [PMID:17913302, PMID:20374418, PMID:32285253]. t½ Not characterized in humans (no pharmacokinetic data). Community/anecdotal only: ~5-25 mg per day, oral. No validated or approved human dose exists. 6 PubMed View Profile https://www.bodyhackguide.co/compound/9-mbc ### Cartalax Recovery Preclinical Cartalax is a short synthetic peptide developed in Russia by Vladimir Khavinson and colleagues at the St. t½ No published human or animal pharmacokinetic data for Cartalax. As a small (~446.5 Da) tetrapeptide, rapid plasma hydrolysis (on the order of minutes) is expected, consistent with other Khavinson short peptides, but this has not been directly measured. 20 mg oral/sublingual once daily for 10 days; 60-90 day washout 6 PubMed View Profile https://www.bodyhackguide.co/compound/cartalax ### Chaga Adaptogen Preclinical Chaga (Inonotus obliquus) is a parasitic fungus that grows almost exclusively on birch trees (primarily Betula pendula and Betula pubescens) across the cold-temperate and subarctic forests of Siberia, Northern Russia, Scandinavia, the Baltic states, Canada, Alaska, and the northern tier of the continental United States. 6 PubMed View Profile https://www.bodyhackguide.co/compound/chaga ### GHK-Cu ### Prostamax Other Preclinical ### Comfrey Herbal Preclinical Comfrey (Symphytum officinale) is one of the most mechanistically interesting — and simultaneously one of the most legally and toxicologically constrained — herbs in traditional European medicine. 5 PubMed View Profile https://www.bodyhackguide.co/compound/comfrey ### Melanotan-1 ### P-21 Nootropic Peptide Preclinical ### SS-31 ### Modafinil Nootropics Preclinical Modafinil is a prescription wakefulness-promoting agent approved by the US Food and Drug Administration in December 1998 under the brand name Provigil (Cephalon, now Teva) for the treatment of excessive daytime sleepiness associated with narcolepsy, shift work sleep disorder, and as an adjunct to continuous positive airway pressure therapy in obstructive sleep apnea. 3 PubMed View Profile https://www.bodyhackguide.co/compound/modafinil ### NA-Semax Nootropic Peptide Preclinical ### NSI-189 Nootropics Phase 2 NSI-189 is a novel synthetic compound developed by Neuralstem Inc. 3 PubMed View Profile https://www.bodyhackguide.co/compound/nsi-189 ### Curcumin Antioxidants Preclinical ### HGH Fragment 176-191 Metabolic & Weight Loss Phase 2 ### NA-Semax Amidate Nootropic Peptide Preclinical ### Pineleon Bioregulator Peptide Preclinical ### Testagen Other Preclinical ### Thymalin ### Vitamin K2 Foundational Preclinical ### AOD-9604 Metabolic & Weight Loss Phase 3 ### Chonluten Recovery Preclinical Chonluten is a bioregulator preparation originating from Vladimir Khavinson's St. t½ Not characterized in humans; no modern pharmacokinetic data exist. Short Khavinson peptides of this class are presumed to undergo rapid plasma hydrolysis (order of minutes). 20 mg oral once daily for 10 days; 60-day washout 1 PubMed View Profile https://www.bodyhackguide.co/compound/chonluten ### Dihexa Nootropics Preclinical Dihexa is a synthetic peptide analogue of the angiotensin IV metabolite LVV-hemorphin-7, developed at Washington State University. t½ Not characterized in humans. Dihexa was engineered for metabolic stability (resistant to plasma and enzymatic degradation) and blood-brain-barrier penetration; in preclinical work its central procognitive effects appear to outlast its plasma presence. 5 to 40 mg oral per day (anecdotal range; no established human dose) 1 PubMed View Profile https://www.bodyhackguide.co/compound/dihexa ### Epithalon Longevity & Cellular Health Preclinical ### Magnesium Foundational Preclinical ### P-21 Amidate Nootropic Peptide Preclinical ### PE-22-28 Nootropics Preclinical PE-22-28 is a synthetic seven-amino-acid peptide (sequence PAGASRLLLLTGEIDLP derivative, commonly truncated to PE-22-28 as shorthand for "position 22-28" within the parent humanin-family sequence) that was designed as an analog of Humanin with specific interest in activity at glutamate transporter regulation and cytoprotective signaling relevant to depression and neuroprotection. t½ Not characterized in humans. As a small 7-amino-acid peptide a short plasma half-life is expected; in mice the parent peptide spadin lost antidepressant activity by about 7 hours after a single dose, while modified analogs (e.g., G/A-PE 22-28) extended the behavioral effect to roughly 21-23 hours [PMID:28955242]. 250-2000 mcg subcutaneous per dose (empirical research-chemical community range; no clinically validated human dose exists; effective preclinical rodent doses were far lower, ~3 mcg/kg). 1 PubMed View Profile https://www.bodyhackguide.co/compound/pe-22-28 ### Phenylpiracetam Nootropics Russia Approved Phenylpiracetam is a Russian-developed phenyl derivative of piracetam with a dramatically higher potency and stimulant profile. 1 PubMed View Profile https://www.bodyhackguide.co/compound/phenylpiracetam ### Semax P-21 Nootropic Peptide Preclinical Semax P-21 is a hybrid synthetic peptide combining structural motifs from Semax and P-21 into a single molecule. t½ No combined-product pharmacokinetics exist. Semax (intranasal): the intact peptide is rapidly metabolized (on the order of minutes), though downstream BDNF/neurotrophic effects outlast the peptide itself. P-21 / P021: a small molecule with pharmacokinetics suitable for oral dosing in animal studies; no human PK data. 1 PubMed View Profile https://www.bodyhackguide.co/compound/semax-p21 ### Tadalafil Metabolic Preclinical ### 5-Amino-1MQ Weight Loss Preclinical ### Acetyl Hexapeptide-8 ### Adalank Nootropic Peptide Preclinical / Research compound Adalank is a hybrid research peptide combining structural elements of Adamax (the adamantyl-modified Semax analog) and Selank (the anxiolytic Pro-Gly-Pro tuftsin analog). t½ The commonly cited ~72-hour "functional duration" is an unverified community/vendor claim, not a measured value - no pharmacokinetic study of Adalank has ever been run. The figure is extrapolated from parent Adamax marketing claims. Actual serum half-life is unknown; there is no published PK data. 200-1200 mcg per dose (intranasal or subcutaneous), 1-2x daily Preclinical View Profile https://www.bodyhackguide.co/compound/adalank ### Adamax Adamax is a synthetic nonapeptide (Ac-MEHFPGPAG-NH2) classified as a designer analog of Semax. t½ No pharmacokinetic data. Community reports describe a subjectively long duration of effect (~2-3 days), supporting every-other-day or 3x/week dosing; serum half-life not characterized. 500-2000 mcg subcutaneous (community research dosing) Preclinical View Profile https://www.bodyhackguide.co/compound/adamax ### AHK-Cu Skin & Hair Preclinical ### AICAR (acadesine) Metabolic Phase 3 ### Albuterol (salbutamol) Pharmaceutical FDA Approved ### Alpha-Lipoic Acid Foundational Preclinical Alpha-lipoic acid (ALA), also known as thioctic acid or 1,2-dithiolane-3-pentanoic acid, is a sulfur-containing eight-carbon fatty acid derivative synthesized endogenously in mitochondria by lipoic acid synthase (LIAS). Preclinical View Profile https://www.bodyhackguide.co/compound/alpha-lipoic-acid ### Amlexanox Metabolic FDA Approved ### Aniracetam Nootropics Approved (Italy) Aniracetam is a pyrrolidinone in the racetam family, developed by Hoffmann-La Roche under the code Ro 13-5057. t½ About half an hour for the parent drug in humans. Plasma elimination half-life was 0.47 to 0.49 hours after a single 400 mg oral dose in 20 healthy male volunteers (PMID: 19025058). Aniracetam is extensively metabolized to N-anisoyl-GABA and anisic acid; in six elderly hospitalized patients with cerebrovascular disease and reduced creatinine clearance, metabolite half-life was 4 to 7 times longer than in young volunteers (PMID: 9062694). Preclinical View Profile https://www.bodyhackguide.co/compound/aniracetam ### Apigenin Flavonoid Preclinical ### ATX-304 Metabolic & Weight Loss Phase IIa Clinical Trials ATX-304 (also known as O-304) is an orally bioavailable, first-in-class pan-AMPK activator with a mild mitochondrial-uncoupling effect. Preclinical View Profile https://www.bodyhackguide.co/compound/atx-304 ### BAC Water ### Bemethyl (bemitil) Nootropics Approved (Russia) Bemethyl, known in the Russian literature as bemitil and sold in the region under names including Metaprot, Bemactor and Antihot, is 2-ethylthiobenzimidazole, normally handled as the hydrobromide salt. t½ Not established in humans; in healthy volunteers given a single 250 mg oral dose of the Metaprot capsule form, peak serum ethylthiobenzimidazole averaged 0.91 microg/mL at about 1.06 h, and no terminal half-life was reported (PMID: 21870773) Preclinical View Profile https://www.bodyhackguide.co/compound/bemethyl ### Berberine Metabolic Preclinical ### Beta-carotene Carotenoid Preclinical ### Biotin Vitamin Preclinical ### BPC-157/TB-500 Blend Recovery Preclinical Combined healing peptide blend. t½ BPC-157: short - under ~30 min in animal PK studies (rats/dogs); no human PK data. TB-500 (thymosin beta-4): active fragment ~30 min, though tissue effects are prolonged. Dosed per component (a fixed daily blend over-doses TB-500 - see notes). BPC-157: 250-500 mcg once daily SUBQ. TB-500 (thymosin beta-4): 2-2.5 mg twice weekly during a 4-6 week loading phase, then 2-2.5 mg once weekly for maintenance (~5 mg/week during loading). If a pre-blended fixed-ratio daily vial is used, its TB-500 fraction should be ~250-350 mcg per injection so the weekly TB-500 total stays near ~5 mg. Preclinical View Profile https://www.bodyhackguide.co/compound/bpc-tb-blend ### CAG Recovery Not a defined single compound CAG is not a standardized research-peptide designation. t½ Unknown Preclinical View Profile https://www.bodyhackguide.co/compound/cag ### Cardarine (GW501516) Metabolic Discontinued ### Choline Essential Nutrient Preclinical ### CJC-1295 No-DAC (Mod GRF 1-29) ### CJC-1295 with DAC Growth Hormone / IGF-1 Axis Preclinical / Research peptide CJC-1295 with DAC is the long-acting variant of CJC-1295. t½ ~6-8 days (DAC-bound albumin depot) 1000-2000 mcg (1-2 mg) per week Preclinical View Profile https://www.bodyhackguide.co/compound/cjc-1295-with-dac ### CJC-1295 with DAC Growth Hormone / IGF-1 Axis Phase 2 CJC-1295 with DAC (Drug Affinity Complex) is a modified form of CJC-1295 that incorporates a maleimidopropionic acid (MPA) reactive group at the C-terminus. t½ 6–8 days (due to albumin binding via DAC) 1,000–2,000 mcg (1–2 mg) per injection Preclinical View Profile https://www.bodyhackguide.co/compound/cjc-1295-dac ### CJC-1295/Ipamorelin Blend ### Clenbuterol Controlled Substances Preclinical ### Coenzyme Q10 Foundational Preclinical Coenzyme Q10 (CoQ10), also known as ubiquinone-10, ubidecarenone, or simply "coenzyme Q," is a lipid-soluble benzoquinone compound with a 50-carbon isoprenoid side chain (decaprenyl tail) that anchors it within the inner mitochondrial membrane. Preclinical View Profile https://www.bodyhackguide.co/compound/coq10 ### Copper Mineral Preclinical ### Cortagen Longevity Preclinical ### Creatine Foundational Preclinical Creatine is the most-researched nutritional supplement in sports science and has emerged over the past decade as a cornerstone compound in the broader longevity conversation, extending beyond its traditional ergogenic applications into cognitive performance, brain health in aging, sarcopenia prevention, bone health, and recovery from traumatic brain injury. Preclinical View Profile https://www.bodyhackguide.co/compound/creatine ### Cyclazodone Nootropics Preclinical Cyclazodone is the N-cyclopropyl derivative of pemoline, a 4-oxazolidinone stimulant. Preclinical View Profile https://www.bodyhackguide.co/compound/cyclazodone ### Dasatinib Senolytics Preclinical Other Approved (Japan) ### DMHA ### Dream Spray This is a duplicate/alias entry. ### EGCG (Epigallocatechin Gallate) Flavonoid Preclinical ### Eloralintide (LY3841136) Weight Loss Phase 3 ### Exenatide Weight Loss FDA-approved Exenatide (Byetta, Bydureon) is a synthetic exendin-4 GLP-1 receptor agonist, FDA-approved for type 2 diabetes, that lowers blood glucose and curbs appetite. t½ Immediate-release (Byetta): terminal half-life about 2.4 hours, cleared mainly by the kidneys. Extended-release (Bydureon): the same peptide is released slowly from biodegradable microspheres over roughly 10 weeks, reaching steady-state plasma levels by about 6 to 7 weeks. 5 to 10 mcg twice daily (Byetta, immediate-release) or 2000 mcg (2 mg) once weekly (Bydureon, extended-release) Preclinical View Profile https://www.bodyhackguide.co/compound/exenatide ### Fasoracetam (NS-105) Nootropics Phase 2 Fasoracetam is a racetam developed by Nippon Shinyaku in Japan under the code NS-105 and taken into clinical development for vascular dementia. t½ Mean terminal half-life 4.82 hours, range 4.06 to 6.99 hours, after single oral doses in adolescents aged 12 to 17, with the drug excreted for the most part unchanged through the kidneys (PMID: 29339723). After intravenous dosing in animals, elimination half-life was 0.67 hours in rats, 2.1 hours in dogs and 1.3 hours in monkeys, with high systemic availability after oral dosing in all three species (PMID: 10604039). Preclinical View Profile https://www.bodyhackguide.co/compound/fasoracetam ### Finasteride Pharmaceutical Preclinical ### Fisetin Flavonoid Preclinical ### Fladrafinil (CRL-40,941) Nootropics Preclinical Fladrafinil, coded CRL-40,941, is the N-hydroxy analog of flmodafinil and the difluorinated counterpart of adrafinil. t½ Not established in humans; after a single 20 mg oral dose in six volunteers, urinary fladrafinil peaked at 2 to 4 h and stayed detectable for up to 12 h, while the metabolite flmodafinil was detectable for about 8 days and the acid and sulfone metabolites for about two weeks (PMID: 42210629) Preclinical View Profile https://www.bodyhackguide.co/compound/fladrafinil ### Folate Vitamin Preclinical ### GB-115 Nootropics Approved (Russia) GB-115 is a synthetic dipeptide, N-(6-phenylhexanoyl)glycyl-L-tryptophan amide, designed at the Zakusov Research Institute of Pharmacology in Moscow. t½ Not established in humans; the published rat pharmacokinetic work reported an absolute oral bioavailability of 4.65 percent for the crystalline substance and did not report a terminal half-life (PMID: 18457023) Preclinical View Profile https://www.bodyhackguide.co/compound/gb-115 ### Glow Blend Recovery Preclinical GHK-Cu + BPC-157 + TB-500 blend for skin and recovery. t½ Varies by component - the blend has no single half-life. BPC-157 and the TB-500 (thymosin beta-4) fragment are small peptides cleared over hours; GHK-Cu is a short-lived tripeptide-copper complex. Community dosing frequency is driven by empirical practice, not by measured pharmacokinetics of the blend. Blend - stated per component: GHK-Cu 1000-2000 mcg/day; BPC-157 250-500 mcg/dose; TB-500 2000-2500 mcg/dose. No validated dose exists for the combination (Research Use Only). Preclinical View Profile https://www.bodyhackguide.co/compound/glow-blend ### Glycine Foundational Preclinical Glycine is the simplest amino acid—a single hydrogen atom replacing the typical side chain found in other proteinogenic amino acids—yet it performs an wide range of biological functions. Preclinical View Profile https://www.bodyhackguide.co/compound/glycine ### Gotu Kola herb Preclinical ### Hawthorn herb Preclinical ### HCG Hormonal FDA-approved ### HMG (Human Menopausal Gonadotropin) ### Horny Goat Weed herb Preclinical ### Indole-3-propionamide (IPAM) Other Preclinical IPAM is the market abbreviation for indole-3-propionamide, the amide of indole-3-propionic acid and a close structural relative of melatonin. t½ Not established in humans; after intraperitoneal administration of 0.5 mg/kg to one-month-old male Sprague-Dawley rats, brain concentrations were 691 pg indole per mg protein at 2 h, 562 at 4 h and 361 at 8 h, which the authors described as a long half-life relative to melatonin (PMID: 20421998) Preclinical View Profile https://www.bodyhackguide.co/compound/indole-3-propionamide ### Iodine Mineral Preclinical Iodine is a halogen trace mineral and an obligate substrate for thyroid hormone synthesis — the single biochemical fact that dominates all clinical thinking about iodine. Preclinical View Profile https://www.bodyhackguide.co/compound/iodine ### Iron Mineral Preclinical Iron is a trace mineral with a biochemistry dominated by a single chemical property — the reversible one-electron redox between Fe²⁺ (ferrous) and Fe³⁺ (ferric) — that makes it indispensable for oxygen transport, electron transfer, and hundreds of enzymatic reactions, and simultaneously dangerous when unchaperoned in cells. Preclinical View Profile https://www.bodyhackguide.co/compound/iron ### J147 Nootropics Phase 2 J147 is a synthetic phenyl hydrazide derived from curcumin, made at the Salk Institute for Biological Studies. t½ Not established in humans; the phase 1 study measured terminal half-life but has not reported results (NCT03838185). After oral dosing in mice, half-life was about 1.5 hours in plasma and 2.5 hours in brain, with oral bioavailability calculated at 28 percent and a brain to blood ratio of about 0.5 (PMID: 23673233). Preclinical View Profile https://www.bodyhackguide.co/compound/j-147 ### Kavain Nootropics Preclinical for isolated kavain (in-vitro and animal mechanistic data). Human randomized controlled trials exist for the parent standardized kava extract, of which kavain is the principal kavalactone; the single molecule itself has not been trialed alone. Kavain (kawain) is the principal kavalactone in kava (Piper methysticum) and the main compound behind kava's calming, anxiolytic effect. t½ Not firmly established for isolated kavain in humans. Kavalactones are lipophilic and rapidly absorbed, with subjective effects generally lasting a few hours. Limited pharmacokinetic data preclude a precise elimination half-life. 50-250 mg Preclinical View Profile https://www.bodyhackguide.co/compound/kavain ### Kisspeptin-10 (KSPTN) Other Clinical (investigational) KSPTN is the vendor shorthand for kisspeptin, a naturally occurring peptide encoded by the KISS1 gene and the master upstream regulator of the reproductive (hypothalamic-pituitary-gonadal) hormone axis. t½ Kisspeptin-10: very short, reported on the order of ~4 minutes (rapid plasma clearance). Kisspeptin-54 is longer-acting (tens of minutes). The brief half-life is why human studies dose it intravenously by bolus or continuous infusion. 20-100 mcg Preclinical View Profile https://www.bodyhackguide.co/compound/ksptn ### KLOW Blend Recovery Preclinical GHK-Cu + BPC-157 + TB-500 + KPV blend. Per manufacturer protocol Preclinical View Profile https://www.bodyhackguide.co/compound/klow-blend ### KW-6356 Nootropics Phase 2b (program discontinued) KW-6356 is a selective adenosine A2A receptor antagonist/inverse agonist developed by Kyowa Kirin and studied for Parkinson's disease, both as monotherapy and as an add-on to levodopa. Preclinical View Profile https://www.bodyhackguide.co/compound/kw-6356 ### Larazotide (AT-1001) Immune & Inflammation Phase 3 ### Levo-tetrahydropalmatine (l-THP) Nootropics Approved (China) Levo-tetrahydropalmatine, usually written l-THP, is an isoquinoline alkaloid found in plants of the Corydalis and Stephania genera. t½ Not established in the sources retrieved; a randomized, double-blind, placebo-controlled human study collected full plasma pharmacokinetic profiles in 19 cocaine users receiving l-THP 30 mg twice daily for 4 days but did not report a terminal half-life (PMID: 27363313) Preclinical View Profile https://www.bodyhackguide.co/compound/l-thp ### LGD-4033 (Ligandrol) Performance Phase 2 ### Lipo-C Weight Loss No clinical trials of the blend (marketed compounded injection) Lipo-C (also sold as a MIC or "lipotropic" injection) is a compounded blend of methionine, inositol, and choline, usually with vitamin B12 and sometimes L-carnitine, marketed by medspas and weight-loss clinics to support fat metabolism and energy. t½ Not applicable to the blend; the water-soluble components (choline, inositol, B-vitamins, carnitine) are cleared over hours to a few days, and excess is largely excreted. 1 mL of a compounded MIC blend intramuscularly, 1 to 2x per week. No standardized dose exists; concentrations vary by compounding pharmacy. Preclinical View Profile https://www.bodyhackguide.co/compound/lipo-c ### Lycopene Carotenoid Preclinical ### Melanotan 2 ### Melanotan I Other FDA Approved Melanotan I (afamelanotide) is a linear synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) with the substitution of norleucine at position 4 and D-phenylalanine at position 7. t½ Controlled-release subcutaneous implant (Scenesse): high inter-subject variability; median Tmax ~36 h, mean Cmax ~3.7 ng/mL, apparent terminal half-life ~15 h, with plasma levels measurable to ~96 h post-dose (FDA pharmacokinetics, n=12). Injected/bolus free peptide: peak plasma at ~1-2 h with an elimination half-life of ~30 minutes; the Nle4/D-Phe7 modifications prolong biological (melanogenic) activity well beyond plasma clearance. 16 mg Preclinical View Profile https://www.bodyhackguide.co/compound/melanotan-i ### Melanotan II This is a duplicate/alias entry. ### Meldonium Pharmaceutical Approved (Latvia) ### Metformin Metabolic Preclinical ### Minoxidil Skin & Hair FDA-Approved ### Mirabegron Pharmaceutical FDA Approved ### Mucuna Pruriens herb Preclinical ### N-Acetyl-Selank ### N-Acetyl-Semax This is a duplicate/alias entry. ### NAC Antioxidants Preclinical ### NAD+ Carnitine Blend Weight Loss Individual components clinically studied (mostly oral); the injectable blend itself has no clinical trials. NAD+ and carnitine amino blend for energy and metabolism. NAD+ 50-250 mg plus L-carnitine 250-1000 mg per session (community / IV-clinic practice; not trial-validated). Start at the low end of both. Preclinical View Profile https://www.bodyhackguide.co/compound/nad-carnitine-blend ### Neboglamine (CR 2249) Nootropics Phase 2 Neboglamine, originally coded CR 2249 and given the international non-proprietary name nebostinel, is a glutamic acid derivative developed by Rotta Research Laboratorium in Monza, Italy, and later carried by Rottapharm. t½ Not established. No human or animal pharmacokinetic study for neboglamine has been published, and no phase 1 data are available. Preclinical View Profile https://www.bodyhackguide.co/compound/neboglamine ### Nefiracetam Nootropics Clinical (marketed in Japan; research-use in US) Nefiracetam (DM-9384) is a fat-soluble pyrrolidone (racetam-class) nootropic research compound developed in Japan and studied for cognitive impairment in cerebrovascular and Alzheimer-type dementia. t½ Approx. 3-8 hours (reported) Preclinical View Profile https://www.bodyhackguide.co/compound/nefiracetam ### Niacin Vitamin Preclinical ### NMN Longevity Preclinical ### Noopept + Choline Chloride Blend ### Orforglipron Weight Loss FDA Approved Orforglipron (also known as LY3502970) is Eli Lilly's oral, non-peptide, small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist, approved in the US for weight management and submitted to the FDA for type 2 diabetes. t½ ~29-49 hours (supports once-daily oral dosing) Preclinical View Profile https://www.bodyhackguide.co/compound/orforglipron ### Ostarine (Enobosarm, MK-2866) Performance Phase 3 ### Oxiracetam Nootropics Approved (Italy) Oxiracetam is a hydroxylated analog of piracetam, developed in Italy in the early 1980s under the code ISF 2522 and also known as CGP 21690E. t½ About 8 hours in healthy adults. Mean terminal half-life was 7.7 hours in healthy non-geriatric subjects and 12.3 hours in elderly patients after oral dosing (PMID: 2253653), and 10.6 to 68.1 hours in patients with renal impairment, correlating with creatinine clearance (PMID: 2253654). More than 90 percent of an intravenous dose is recovered unchanged in urine within 48 hours, and absolute oral bioavailability was 75 percent in healthy volunteers (PMID: 6519128). Preclinical View Profile https://www.bodyhackguide.co/compound/oxiracetam ### PDRN Skin & Hair Phase 4 ### PEG-MGF Performance Preclinical ### Phenibut Nootropics Prescription Medicine (Russia/CIS) / Unregulated Elsewhere Phenibut is the common Western name for β-phenyl-γ-aminobutyric acid (beta-phenyl-GABA; Russian trade names Phenibut/Фенибут, Noofen, Anvifen), a Soviet-era anxiolytic and nootropic developed in the 1960s at the Herzen State Pedagogical Institute in Leningrad under Vsevolod Vasilievich Perekalin. t½ 5-8 hours (plasma); central CNS effect 10-16 hours Preclinical View Profile https://www.bodyhackguide.co/compound/phenibut ### PNC-27 Other Preclinical PNC-27 is a p53-derived peptide that selectively induces membranolysis in cancer cells. t½ Unknown (no published PK data) Preclinical View Profile https://www.bodyhackguide.co/compound/pnc-27 ### PRL-8-53 Nootropics Discontinued PRL-8-53 is a benzoic acid ester with a benzylmethylamino side chain, first described by N. t½ Not established. No pharmacokinetic study in humans or in any animal species has been published for PRL-8-53. Preclinical View Profile https://www.bodyhackguide.co/compound/prl-8-53 ### Pterostilbene Stilbene Polyphenol Preclinical ### Quercetin Flavonoid Preclinical ### RAD-140 (Testolone) Performance Phase 1 ### Rapamycin Longevity Preclinical ### Riboflavin Vitamin Preclinical Riboflavin (vitamin B2) is a water-soluble vitamin that serves as the precursor to two universal flavoprotein cofactors — flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) — which together serve as electron-carrying prosthetic groups in more than 90 human enzymes including Complex I and Complex II of the mitochondrial electron transport chain, the acyl-CoA dehydrogenases of fatty acid β-oxidation, glutathione reductase (the enzyme that regenerates reduced glutathione for antioxidant defense), methylenetetrahydrofolate reductase (MTHFR, the critical folate cycle enzyme), pyridoxine-5-phosphate oxidase (PNPO, which converts dietary B6 vitamers to active PLP), and kynurenine monooxygenase in the tryptophan-to-NAD+ pathway. Preclinical View Profile https://www.bodyhackguide.co/compound/riboflavin ### Sabroxy (Oroxylin A) Nootropics Preclinical, with one supporting human RCT Sabroxy is a standardized Oroxylum indicum (Indian trumpet tree) bark extract - typically 10% oroxylin A - sold as a nootropic supplement ingredient. 500-1,000 mg Preclinical View Profile https://www.bodyhackguide.co/compound/sabroxy ### Semax/Selank Blend Nootropics Preclinical (no trials on the blend; components studied separately, mostly in Russia) Combined nootropic and anxiolytic peptide blend. t½ Both component peptides have short plasma half-lives (on the order of minutes) but a prolonged duration of central action, attributed to the protective C-terminal Pro-Gly-Pro sequence they share. Blend-specific pharmacokinetics have not been characterized. Semax ~250-600 mcg + Selank ~250-300 mcg per day, intranasal (community-reported; no established blend dose) Preclinical View Profile https://www.bodyhackguide.co/compound/semax-selank-blend ### Shilajit Adaptogen Preclinical Shilajit (Sanskrit: shilajatu, αñ╢αñ┐αñ▓αñ╛αñ£αññαÑü, literally "rock-conqueror" or "rock-invincible"; Hindi/Urdu: shilajit; Persian and Central Asian: mumijo, moomiyo, mumiyo; Pashto/Afghan: salajeet; Latin pharmacopeial: Asphaltum Punjabinum) is a blackish-brown, sticky, resin-like mineral-organic exudate that oozes from cracks in rock formations in high-altitude mountain ranges, most famously the Himalayas and Karakoram but also the Altai, Tien Shan, Caucasus, and Hindu Kush ranges. Preclinical View Profile https://www.bodyhackguide.co/compound/shilajit ### Sleep Research Blend ### SLU-PP-915 Metabolic Preclinical SLU-PP-915 is an experimental agonist of the estrogen-related receptors, a family of three orphan nuclear receptors called ERR-alpha, ERR-beta and ERR-gamma that control genes for mitochondrial biogenesis, oxidative phosphorylation, fatty acid oxidation and the Krebs cycle. t½ Not established in humans; in mice it is orally bioavailable and active by both oral and intraperitoneal routes, unlike its predecessor SLU-PP-332 (PMID: 41421047) Preclinical View Profile https://www.bodyhackguide.co/compound/slu-pp-915 ### Snap-8 Skin & Hair Preclinical t½ Not characterized (topical peptide) ### Sobetirome (GC-1) Metabolic Discontinued Sobetirome, also called GC-1 and later QRX-431, is a synthetic analog of thyroid hormone made in Thomas Scanlan laboratory and first described in 1998 as a high-affinity, subtype-selective agonist for the thyroid hormone receptor (PMID: 9653548). t½ Not established in humans; no peer-reviewed human pharmacokinetic study has been published, and the phase 1 program results were not reported in the peer-reviewed literature (PMID: 19002578) Preclinical View Profile https://www.bodyhackguide.co/compound/sobetirome ### Spermidine Polyamine Preclinical ### SR-9009 (stenabolic) Metabolic Preclinical SR-9009, sold as stenabolic, is a synthetic agonist of the nuclear receptors REV-ERB-alpha and REV-ERB-beta. t½ Not established in humans; no human pharmacokinetic study has been published. In the mouse experiments that produced the metabolic findings the compound was given by intraperitoneal injection rather than orally (PMID: 22460951) Preclinical View Profile https://www.bodyhackguide.co/compound/sr-9009 ### Sulforaphane Isothiocyanate Preclinical ### Sunifiram (DM-235) Nootropics Preclinical Sunifiram, also called DM-235, is a piperazine that came out of an academic medicinal chemistry program at the University of Florence, not out of a pharmaceutical company. t½ Not established. No pharmacokinetic study in humans or animals has been published, and the group that discovered the compound stated that its long-term toxicity was unknown (PMID: 25831025). Preclinical View Profile https://www.bodyhackguide.co/compound/sunifiram ### T3/T4 Thyroid Blend ### TAK-653 Nootropics Phase II Clinical Trials TAK-653 is a novel positive allosteric modulator (PAM) of AMPA-type glutamate receptors developed by Takeda Pharmaceuticals. t½ 6-10 hours (estimated) 0.1 mg - 6 mg Preclinical View Profile https://www.bodyhackguide.co/compound/tak-653 ### Taurine Foundational Preclinical Taurine is a sulfonic acid (not technically an amino acid, though often classified as one) that ranks among the most abundant free amino acid-like molecules in human tissues. Preclinical View Profile https://www.bodyhackguide.co/compound/taurine ### Thiamine Vitamin Preclinical Thiamine (vitamin B1) is the original vitamin — the deficiency syndrome beriberi was the clinical problem that gave rise to the entire vitamin concept, and the compound isolated from rice polishings by Jansen and Donath in 1926 and synthesized by Robert Williams in 1936 was literally the first "vital amine" (Casimir Funk coined the term vitamine in 1912 after investigating the anti-beriberi factor). Preclinical View Profile https://www.bodyhackguide.co/compound/thiamine ### Tropisetron Pharmaceutical Approved (Japan) ### TUDCA Liver Support Preclinical ### Vasodrive Amino Blend ### VIP Nootropic Clinical VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide and hormone that is widely expressed throughout the central and peripheral nervous systems, gastrointestinal tract, and immune system. t½ ~1-2 minutes (plasma). VIP is very rapidly degraded by circulating peptidases, so systemic exposure is extremely short-lived regardless of administration route. Subcutaneous or intranasal absorption may modestly prolong the apparent duration of local/systemic effect, but this has not been well characterized in humans. 50 mcg Preclinical View Profile https://www.bodyhackguide.co/compound/vip ### Vitamin B12 Foundational Preclinical Vitamin B12 (cobalamin) is a water-soluble cobalt-containing vitamin that serves as a coenzyme for two critical enzymes in human metabolism: methionine synthase (cytoplasmic) and L-methylmalonyl-CoA mutase (mitochondrial). Preclinical View Profile https://www.bodyhackguide.co/compound/vitamin-b12 ### Vitamin B6 Vitamin Preclinical Vitamin B6 is a water-soluble B-vitamin family comprising six interconvertible vitamers — pyridoxine, pyridoxal, pyridoxamine, and their phosphorylated forms — that converge on the single active coenzyme pyridoxal 5-phosphate (PLP, also written P5P). Preclinical View Profile https://www.bodyhackguide.co/compound/vitamin-b6 ### YK-11 Performance Preclinical YK-11 is a synthetic steroid, not a nonsteroidal SARM, despite being sold alongside them. t½ Not established. In a human elimination study using deuterium-labeled YK-11, no intact parent compound was seen in urine; unconjugated metabolites disappeared within 24 hours and glucuronidated and sulfated metabolites remained traceable beyond 48 hours (PMID: 30379415) Preclinical View Profile https://www.bodyhackguide.co/compound/yk-11 ### Zeaxanthin Carotenoid Preclinical ### Zinc Foundational Preclinical Zinc is an essential trace mineral — the second most abundant metal ion in the human body after iron — and one of the most biologically versatile elements in all of physiology. Preclinical View Profile https://www.bodyhackguide.co/compound/zinc Last updated: October 3, 2026 Research drops ## Get the research before it hits Reddit. New compound profiles, dosing guides and the studies worth reading. Sent on no set schedule. Unsubscribe anytime. We never share your email. #### Product - Nootropics: https://www.bodyhackguide.co/nootropics - Wiki: https://www.bodyhackguide.co/wiki - Tools: https://www.bodyhackguide.co/tools - Compare: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors #### Learn - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides - Brain Health: https://www.bodyhackguide.co/brain-health - Cheat Sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download - Glossary: https://www.bodyhackguide.co/glossary #### Company - About: https://www.bodyhackguide.co/about - Editorial: https://www.bodyhackguide.co/editorial-standards - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Affiliate Disclosure: https://www.bodyhackguide.co/affiliate-disclosure © 2026 BodyHackGuide · Research purposes only. Discord: https://discord.gg/Mhq5UdRYBA Reddit: https://reddit.com/r/BodyHackGuide Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) Shop BHG Labs 20% off your first order, code BHG20: https://bhglabs.co/shop/?ref=zmgqyxku&coupon=BHG20 ## Structured data ```json [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Wiki" } ] }, { "@context": "https://schema.org", "@type": "CollectionPage", "name": "Research Compound Wiki: 273 Peptide, Nootropic & Research Molecule Profiles", "description": "Evidence-based profiles for 273 research compounds across 65 categories. PubMed-backed data, dosing ranges, half-lives, mechanisms of action, and vendor pricing.", "url": "https://www.bodyhackguide.co/wiki", "numberOfItems": 273, "dateModified": "2026-10-03", "isPartOf": { "@type": "WebSite", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, { "@context": "https://schema.org", "@type": "ItemList", "name": "Most-Studied Research Compounds", "description": "The 20 most-studied compounds in the BodyHackGuide wiki, ranked by PubMed citation count.", "itemListOrder": "https://schema.org/ItemListOrderDescending", "numberOfItems": 20, "itemListElement": [ { "@type": "ListItem", "position": 1, "url": "https://www.bodyhackguide.co/compound/probiotics", "name": "Probiotics" }, { "@type": "ListItem", "position": 2, "url": "https://www.bodyhackguide.co/compound/melatonin", "name": "Melatonin" }, { "@type": "ListItem", "position": 3, "url": "https://www.bodyhackguide.co/compound/panax-ginseng", "name": "Panax ginseng" }, { "@type": "ListItem", "position": 4, "url": "https://www.bodyhackguide.co/compound/vitamin-e", "name": "Vitamin E" }, { "@type": "ListItem", "position": 5, "url": "https://www.bodyhackguide.co/compound/silymarin", "name": "Silymarin" }, { "@type": "ListItem", "position": 6, "url": "https://www.bodyhackguide.co/compound/beta-sitosterol", "name": "Beta-Sitosterol" }, { "@type": "ListItem", "position": 7, "url": "https://www.bodyhackguide.co/compound/vitamin-a", "name": "Vitamin A" }, { "@type": "ListItem", "position": 8, "url": "https://www.bodyhackguide.co/compound/dhea", "name": "DHEA" }, { "@type": "ListItem", "position": 9, "url": "https://www.bodyhackguide.co/compound/astaxanthin", "name": "Astaxanthin" }, { "@type": "ListItem", "position": 10, "url": "https://www.bodyhackguide.co/compound/caffeine", "name": "Caffeine" }, { "@type": "ListItem", "position": 11, "url": "https://www.bodyhackguide.co/compound/pantothenic-acid", "name": "Pantothenic Acid" }, { "@type": "ListItem", "position": 12, "url": "https://www.bodyhackguide.co/compound/l-carnitine", "name": "L-Carnitine" }, { "@type": "ListItem", "position": 13, "url": "https://www.bodyhackguide.co/compound/inositol", "name": "Inositol" }, { "@type": "ListItem", "position": 14, "url": "https://www.bodyhackguide.co/compound/oleuropein", "name": "Oleuropein" }, { "@type": "ListItem", "position": 15, "url": "https://www.bodyhackguide.co/compound/semaglutide", "name": "Semaglutide" }, { "@type": "ListItem", "position": 16, "url": "https://www.bodyhackguide.co/compound/l-tryptophan", "name": "L-Tryptophan" }, { "@type": "ListItem", "position": 17, "url": "https://www.bodyhackguide.co/compound/nad", "name": "NAD+" }, { "@type": "ListItem", "position": 18, "url": "https://www.bodyhackguide.co/compound/ll-37", "name": "LL-37" }, { "@type": "ListItem", "position": 19, "url": "https://www.bodyhackguide.co/compound/methylene-blue", "name": "Methylene Blue" }, { "@type": "ListItem", "position": 20, "url": "https://www.bodyhackguide.co/compound/hydroxytyrosol", "name": "Hydroxytyrosol" } ] }, { "@context": "https://schema.org", "@type": "DefinedTermSet", "name": "Research Compound Categories", "hasDefinedTerm": [ { "@type": "DefinedTerm", "name": "Adaptogen", "description": "Research compounds in the Adaptogen family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Anabolic Peptide", "description": "Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Antioxidants", "description": "Research compounds in the Antioxidants family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Bioregulator Peptide", "description": "Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Carotenoid", "description": "Research compounds in the Carotenoid family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Cofactor", "description": "Research compounds in the Cofactor family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Cognition, Mood & Neuroprotection", "description": "Research compounds in the Cognition, Mood & Neuroprotection family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Cognitive", "description": "Research compounds in the Cognitive family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Controlled Substances", "description": "Research compounds in the Controlled Substances family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Energy & Performance", "description": "Research compounds in the Energy & Performance family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Enzyme", "description": "Research compounds in the Enzyme family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Essential Nutrient", "description": "Research compounds in the Essential Nutrient family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Flavonoid", "description": "Research compounds in the Flavonoid family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Foundational", "description": "Research compounds in the Foundational family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "GH Secretagogue", "description": "Research compounds in the GH Secretagogue family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "GLP-1 / Glucagon Dual Agonist", "description": "Research compounds in the GLP-1 / Glucagon Dual Agonist family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Growth Hormone", "description": "Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Growth Hormone / IGF-1 Axis", "description": "Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Hepatoprotective Flavonolignan", "description": "Research compounds in the Hepatoprotective Flavonolignan family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Herbal", "description": "Research compounds in the Herbal family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Hormonal", "description": "Research compounds in the Hormonal family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Hormone", "description": "Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Hormone Support", "description": "Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Hormones & Endocrine (Non-GH)", "description": "Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Immune & Inflammation", "description": "Research compounds in the Immune & Inflammation family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Injury, Repair & Recovery", "description": "Research compounds in the Injury, Repair & Recovery family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Isothiocyanate", "description": "Research compounds in the Isothiocyanate family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Liver Support", "description": "Research compounds in the Liver Support family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Liver/Digestive", "description": "Research compounds in the Liver/Digestive family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Longevity", "description": "Research compounds in the Longevity family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Longevity & Cellular Health", "description": "Research compounds in the Longevity & Cellular Health family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Metabolic", "description": "Research compounds in the Metabolic family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Metabolic & Weight Loss", "description": "Research compounds in the Metabolic & Weight Loss family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Mineral", "description": "Research compounds in the Mineral family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Mitochondrial Peptides", "description": "Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Mitochondrial Support", "description": "Research compounds in the Mitochondrial Support family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Myostatin Inhibitor", "description": "Research compounds in the Myostatin Inhibitor family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Nootropic", "description": "Cognitive-enhancing compounds studied for memory, focus, learning, and neuroprotection. Includes racetams, cholinergics like Alpha-GPC, amino-acid derivatives like L-Theanine, and plant adaptogens like Bacopa Monnieri.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Nootropic Adaptogen", "description": "Cognitive-enhancing compounds studied for memory, focus, learning, and neuroprotection. Includes racetams, cholinergics like Alpha-GPC, amino-acid derivatives like L-Theanine, and plant adaptogens like Bacopa Monnieri.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Nootropic Lipid", "description": "Cognitive-enhancing compounds studied for memory, focus, learning, and neuroprotection. Includes racetams, cholinergics like Alpha-GPC, amino-acid derivatives like L-Theanine, and plant adaptogens like Bacopa Monnieri.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Nootropic Peptide", "description": "Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Nootropics", "description": "Cognitive-enhancing compounds studied for memory, focus, learning, and neuroprotection. Includes racetams, cholinergics like Alpha-GPC, amino-acid derivatives like L-Theanine, and plant adaptogens like Bacopa Monnieri.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Other", "description": "Specialty research compounds spanning lipid modulators, longevity molecules, mitochondrial cofactors, and emerging translational targets.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Peptides", "description": "Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Performance", "description": "Research compounds in the Performance family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Performance & Recovery", "description": "Research compounds in the Performance & Recovery family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Pharmaceutical", "description": "Research compounds in the Pharmaceutical family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Polyamine", "description": "Research compounds in the Polyamine family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Polyphenol", "description": "Research compounds in the Polyphenol family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Protein", "description": "Research compounds in the Protein family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Recovery", "description": "Research compounds in the Recovery family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Reproductive Hormone", "description": "Endocrine signaling molecules and analogues studied across metabolic, reproductive, and performance contexts. Includes thyroid analogues, insulin sensitizers, and HPTA-restoring compounds.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Senolytics", "description": "Research compounds in the Senolytics family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Skin & Hair", "description": "Research compounds in the Skin & Hair family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Skin / Cosmetic", "description": "Research compounds in the Skin / Cosmetic family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Skin, Hair & Aesthetics", "description": "Research compounds in the Skin, Hair & Aesthetics family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Sleep", "description": "Research compounds in the Sleep family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Sleep & Circadian", "description": "Research compounds in the Sleep & Circadian family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Stilbene Polyphenol", "description": "Research compounds in the Stilbene Polyphenol family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Supplement", "description": "Research compounds in the Supplement family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Supplies", "description": "Research compounds in the Supplies family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Tanning Peptide", "description": "Short chains of amino acids that signal specific receptors. Research peptides range from healing compounds like BPC-157 and TB-500 to growth-hormone secretagogues like Ipamorelin and Tesamorelin, and GLP-1 agonists like Semaglutide and Retatrutide.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Vitamin", "description": "Research compounds in the Vitamin family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "Weight Loss", "description": "Research compounds in the Weight Loss family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" }, { "@type": "DefinedTerm", "name": "herb", "description": "Research compounds in the herb family, compiled from peer-reviewed literature and clinical trial registries.", "inDefinedTermSet": "https://www.bodyhackguide.co/wiki" } ] } ] ```