--- title: "Tissue Repair Bench: Research Bench — BodyHackGuide" description: "KLOW is sold as an 80 mg co-lyophilized multi-component vial, and the market calls it GHK-Cu, BPC-157, TB-500 and KPV. the listing names none of them. this" lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "WebPage", "name": "Tissue Repair Bench: research bench", "description": "KLOW is sold as an 80 mg co-lyophilized multi-component vial, and the market calls it GHK-Cu, BPC-157, TB-500 and KPV. the listing names none of them. this bench takes the four names apart, adds ARA-290 as the comparison, and says what a COA can and cannot settle.", "url": "https://www.bodyhackguide.co/stack/tissue-repair-bench", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/bhglogo.png" } } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is the Tissue Repair Bench?", "acceptedAnswer": { "@type": "Answer", "text": "KLOW is sold as an 80 mg co-lyophilized multi-component vial, and the market calls it GHK-Cu, BPC-157, TB-500 and KPV. the listing names none of them. this bench takes the four names apart, adds ARA-290 as the comparison, and says what a COA can and cannot settle. it covers 6 compounds: KLOW, BPC-157, TB-500, GHK-Cu, KPV, ARA-290. this is a reference page with no protocol on it." } }, { "@type": "Question", "name": "Is there human data behind the Tissue Repair Bench?", "acceptedAnswer": { "@type": "Answer", "text": "human data: small randomized trials for ARA-290; topical trials only for GHK-Cu; no controlled trial in print for BPC-157; none for the TB-500 fragment, KPV, or the blend. ARA-290: randomized trials with a surrogate-endpoint win and a pain miss. thymosin beta-4: published topical and ophthalmic trials, withdrawn RegeneRx systemic studies, one unpublished Chinese systemic program, terminated epidermolysis bullosa programs. GHK-Cu: one positive and two negative topical trials, nothing systemic. BPC-157: rat work and a null abstract, roughly 200 papers mostly from one group. KPV: mice and rats. the blend: nothing published." } }, { "@type": "Question", "name": "Why does this page not list doses?", "acceptedAnswer": { "@type": "Answer", "text": "the research compounds on this bench are sold for laboratory research, not as supplements. BodyHackGuide publishes roles, evidence, overlap and conflicts for them, never amounts or schedules." } }, { "@type": "Question", "name": "What conflicts with the Tissue Repair Bench?", "acceptedAnswer": { "@type": "Answer", "text": "zinc supplements with GHK-Cu: zinc and copper compete for gut absorption, which is why zinc treats Wilson disease; whether that matters for a copper peptide that does not go through the gut is untested. Wilson disease: a copper complex runs against the treatment by mechanism; no study has looked. cancer history: BPC-157 and thymosin beta-4 promote vessel growth in animal and cell work; no carcinogenicity study exists for BPC-157, the thymosin beta-4 signal is its expression in human tumors rather than a dosing study, and the ARA-290 phase 2b excluded recent malignancy. anticoagulants with BPC-157: rat data only, from one group, never tested in a person. erythropoiesis-stimulating agents or biologic anti-inflammatories with ARA-290: excluded from its phase 2b." } }, { "@type": "Question", "name": "Does BHG Labs sell these?", "acceptedAnswer": { "@type": "Answer", "text": "BHG Labs carries KLOW 80mg, ARA-290 10mg as research-use-only products with a third-party COA on every lot. BPC-157, TB-500, GHK-Cu and KPV are not sold on their own at BHG Labs. BHG Labs and BodyHackGuide are commonly owned." } }, { "@type": "Question", "name": "Who is the Tissue Repair Bench for?", "acceptedAnswer": { "@type": "Answer", "text": "people who have been sold a four-name vial and want to know which names have human data, which have rat data, and which have a COA problem" } } ] }, { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co" }, { "@type": "ListItem", "position": 2, "name": "Stacks", "item": "https://www.bodyhackguide.co/tools/nootropic-stack-builder" }, { "@type": "ListItem", "position": 3, "name": "Tissue Repair Bench", "item": "https://www.bodyhackguide.co/stack/tissue-repair-bench" } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fstack%2Ftissue-repair-bench) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) [Home](/)[Stack Builder](/tools/nootropic-stack-builder)Tissue Repair Bench Research bench · research use only # Tissue Repair Bench KLOW and ARA-290, one name at a time no dosing on this page human data on 2 of 6 the sarcoidosis ARA-290 trials ran four weeks; no other name on this bench has a human timeline for the molecule as sold advanced ## Overview KLOW is sold as an 80 mg co-lyophilized multi-component vial, and the market calls it GHK-Cu, BPC-157, TB-500 and KPV. the listing names none of them. this bench takes the four names apart, adds ARA-290 as the comparison, and says what a COA can and cannot settle. ### Read this first the two products on this page are research use only; the other four names are discussed, not sold. the only document that says what a KLOW vial holds is the certificate for that lot. nothing here is an amount, a schedule, or a route. ## The bench: 6 compounds roles and evidence, not amounts. this page does not publish doses or schedules for research compounds. 1 KLOWno data as a blend the vial as sold: 80 mg total, co-lyophilized, multi-component. BHG Labs states no components and no per-component amounts on the listing; both are deferred to the lot COA. the four-peptide identity below comes from the market name, not from the vendor. evidence: no study of a four-way GHK-Cu, BPC-157, TB-500 and KPV preparation has been published in any species. the closest pairing is BPC-157 with the TB-500 fragment in a rat Achilles tendon model, eight rats per group. watch for: a certificate that gives one purity number and no per-component quantitation does not describe a blend. ask whether it names each component, gives an amount for each, and reports sequence or exact mass for each. copper(II) catalyzes oxidation of neighboring peptide residues (shown for glucagon); whether GHK-Cu degrades its vial-mates has never been tested. 2 BPC-157no peer-reviewed human trial [read the guide](/compound/bpc-157) the 15-amino-acid sequence derived from a gastric-juice protein, with no identified molecular target and roughly 200 PubMed papers, most of them from the Sikiric group. evidence: no randomized human trial published as a full paper. the ulcerative colitis 'phase 2' is a 2005 meeting abstract the FDA reads as null. the rest is a retrospective knee-pain chart review, an interstitial cystitis pilot, and an intravenous safety pilot in two people. a 2025 systematic review counted 35 preclinical studies to one clinical and found no clinical safety data. watch for: FDA put it in 503A category 2 in September 2023 for immunogenicity risk, impurity and characterization complexity, and 'no, or only limited' safety information; it left that list in April 2026 only because the nominators withdrew, which is not a safety clearance. WADA S0, prohibited at all times. angiogenesis through VEGFR2 is shown in chick membrane, rat and cell work, and no carcinogenicity study of any kind exists. 3 TB-500no human trials of the fragment [read the guide](/compound/tb-500) a seven-amino-acid acetylated fragment (Ac-LKKTETQ) of thymosin beta-4, which is a 43-amino-acid peptide. the two are not the same molecule, and the market ships at least three different things under the TB-500 name. evidence: for the fragment itself: nothing in people, and the one registry entry that looks like a trial (NCT07487363) describes itself as a fictional example record. for the full-length peptide, the published trials are topical or ophthalmic: two dry-eye phase 2 studies and a venous ulcer phase 2; a pressure ulcer phase 2 is complete. the three ARISE dry-eye trials are complete, without a paper i could find. the RegeneRx injectable studies were withdrawn before enrolling anyone, a separate Chinese recombinant program has finished two phase 1 studies and is in phase 2 for heart attack with nothing published, and the epidermolysis bullosa programs were terminated. watch for: WADA S2.3, prohibited at all times, with TB-500 named. FDA's concern is immunogenicity from aggregation and impurities plus a total absence of human exposure data. the cancer signal in the literature is on the endogenous peptide's expression in tumors, not on an injected fragment. 4 GHK-Cutopical human trials only [read the guide](/compound/ghk-cu) the copper-binding tripeptide. the positive human data is topical: a randomized diabetic-ulcer trial. the negative human data is topical too: it did not beat placebo on venous ulcers where silver sulfadiazine did, and a laser-resurfacing trial found no objective skin improvement. evidence: no controlled human trial of injected or systemic GHK-Cu has been published. the 'gene expression reset' story is a Broad Institute connectivity-map hit in lung-tissue signatures plus fibroblast culture, generalized by review articles. watch for: how much copper a vial delivers is unpublished. FDA lists injectable GHK-Cu with 'limited data in humans'. 5 KPVanimal and cell only [read the guide](/compound/kpv) the C-terminal tripeptide of alpha-MSH. in cell lines it dampens NF-kB signaling; in mice it eased chemical colitis, mostly when wrapped in nanoparticles or hydrogels, because free KPV is unstable. evidence: no human exposure data by any route, in the FDA's words. no registered trial. watch for: after the first paper, every efficacy study had to protect the peptide to get it anywhere. a lyophilized vial does none of that. 6 ARA-290small human trials [read the guide](/compound/ara-290) the one compound here with a randomized human record beyond topical wound trials. an 11-amino-acid piece of erythropoietin's helix B, built to keep the tissue-protective signal and drop the red-cell one. evidence: sarcoidosis small-fiber neuropathy: a 22-patient pilot reported symptom improvement and a 28-day subcutaneous study added corneal nerve density gains; the 64-patient phase 2b hit its corneal nerve fiber endpoint only in the middle arm and missed on pain. a diabetic neuropathy phase 2 and a 36-volunteer healthy study exist. not approved by FDA or EMA, no completed phase 3, and the sponsor has ceased operations. watch for: non-erythropoietic by design and in animals, with no hematologic signal in the small trials; no trial reported hematocrit as an outcome. WADA S0. Form lyophilized vials, as sold Human data small randomized trials for ARA-290; topical trials only for GHK-Cu; no controlled trial in print for BPC-157; none for the TB-500 fragment, KPV, or the blend BHG Labs carries 2 of 6 Level advanced ### Why these together the four names get bundled because each carries a repair story: BPC-157 for tendon and gut in rats, thymosin beta-4 for wounds and eyes in people, GHK-Cu for skin, KPV for gut lining in mice. ARA-290 sits beside them as the comparison, the one with a randomized program past topical gels. side by side, the evidence shapes do not match. ### Overlap BPC-157 and thymosin beta-4 both promote new vessels and both dampen inflammatory signaling in rodent models; that is where the overlap ends. thymosin beta-4 binds actin, BPC-157 has no identified target. the pair has been used together in one uncontrolled knee series (full-length thymosin beta-4) and one rat tendon study (the TB-500 fragment). GHK-Cu and KPV overlap with nothing here except the word repair. ### Conflicts zinc supplements with GHK-Cu: zinc and copper compete for gut absorption, which is why zinc treats Wilson disease; whether that matters for a copper peptide that does not go through the gut is untested. Wilson disease: a copper complex runs against the treatment by mechanism; no study has looked. cancer history: BPC-157 and thymosin beta-4 promote vessel growth in animal and cell work; no carcinogenicity study exists for BPC-157, the thymosin beta-4 signal is its expression in human tumors rather than a dosing study, and the ARA-290 phase 2b excluded recent malignancy. anticoagulants with BPC-157: rat data only, from one group, never tested in a person. erythropoiesis-stimulating agents or biologic anti-inflammatories with ARA-290: excluded from its phase 2b. ### What the evidence actually is ARA-290: randomized trials with a surrogate-endpoint win and a pain miss. thymosin beta-4: published topical and ophthalmic trials, withdrawn RegeneRx systemic studies, one unpublished Chinese systemic program, terminated epidermolysis bullosa programs. GHK-Cu: one positive and two negative topical trials, nothing systemic. BPC-157: rat work and a null abstract, roughly 200 papers mostly from one group. KPV: mice and rats. the blend: nothing published. ### What people report the market's promise is faster recovery. no controlled human study has measured recovery for any of the four names outside topical wound care; the self-reports STAT collected for BPC-157 were itch, anxiety and anhedonia; and the one blend harm report in the FDA file, causality not established, involved a BPC-157 plus TB-500 research vial. ### Who It's For people who have been sold a four-name vial and want to know which names have human data, which have rat data, and which have a COA problem ### What to Track any local reaction, the COA fields on the lot you received, any itch, anxiety or mood change ## Sourced at BHG Labs Ownership disclosure: BHG Labs and BodyHackGuide are commonly owned. When you buy from BHG Labs, the team behind this site benefits, so read the evidence sections above with that in mind. Third-party COA on every lot. Research use only. Code BHG20 takes 20% off at checkout, and the store links below apply it for you. [ KLOW 80mg $119.99 · lot-numbered · COA on the lot ](https://bhglabs.co/product/klow-80mg/?ref=zmgqyxku&coupon=BHG20)[ ARA-290 10mg $79 · lot-numbered · COA on the lot ](https://bhglabs.co/product/ara-290-10mg/?ref=zmgqyxku&coupon=BHG20) BPC-157, TB-500, GHK-Cu and KPV are not sold on their own at BHG Labs. ### Read the compound guides [BPC-157](/compound/bpc-157) [TB-500](/compound/tb-500) [GHK-Cu](/compound/ghk-cu) [KPV](/compound/kpv) [ARA-290](/compound/ara-290) ## Frequently Asked Questions What is the Tissue Repair Bench? KLOW is sold as an 80 mg co-lyophilized multi-component vial, and the market calls it GHK-Cu, BPC-157, TB-500 and KPV. the listing names none of them. this bench takes the four names apart, adds ARA-290 as the comparison, and says what a COA can and cannot settle. it covers 6 compounds: KLOW, BPC-157, TB-500, GHK-Cu, KPV, ARA-290. this is a reference page with no protocol on it. Is there human data behind the Tissue Repair Bench? Why does this page not list doses? What conflicts with the Tissue Repair Bench? Does BHG Labs sell these? Who is the Tissue Repair Bench for? ## Related Stacks [ Mitochondrial Bench SS-31, NAD+ and glutathione, with the null trials named research bench advanced ](/stack/mitochondrial-bench)[ Beginner Focus The most well-studied nootropic combination $12/mo beginner ](/stack/beginner-focus)[ Mr. Happy Stack The Reddit-famous mood & motivation protocol $25/mo beginner ](/stack/mr-happy-stack) ### Want a personalized stack? The Stack Builder matches you to the right protocol based on your goals, experience level, and medication sensitivities. [Open the Stack Builder](/tools/nootropic-stack-builder) [Back to all stacks](/tools/nootropic-stack-builder) on this page 1. [01 overview](#overview) 2. [02 read this first](#read-first) 3. [03 the bench](#bench) 4. [04 at a glance](#at-a-glance) 5. [05 why these together](#why-together) 6. [06 overlap](#overlap) 7. [07 conflicts](#conflicts) 8. [08 the evidence](#evidence) 9. [09 what people report](#reports) 10. [10 sourced at BHG Labs](#sourced) 11. [11 questions](#faq) Was this page helpful? Yes No ![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub — compound pricing, brain health protocols, dosing tools, and vendor reviews. 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