---
title: "Neuroprotection Stack — Dosing, Timing, Cost ($30/mo)"
description: "Five well-researched compounds that protect neurons, reduce oxidative stress, and support long-term cognitive resilience. 5 compounds, Months — this is a"
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[Home](/)[Stack Builder](/tools/nootropic-stack-builder)Neuroprotection 

Nootropic Stack Protocol

# Neuroprotection

Long-term brain health insurance

$30/mo  Months — this is a long-term investment  beginner 

## Overview

Five well-researched compounds that protect neurons, reduce oxidative stress, and support long-term cognitive resilience.

## The Protocol — 5 Compounds

Each compound is scored for evidence, synergy, and cycling compatibility. Start at the low end of any range and titrate up.

1 DHA

1000 mg 

With meals 

Essential structural component of neuronal membranes

2 Lions Mane

1000 mg 

Morning 

Stimulates NGF for ongoing neurogenesis

3 Creatine

5 g 

Any time 

Provides ATP for neuronal energy, neuroprotective under stress

4 Lithium Orotate

5 mg elemental Li 

Evening 

GSK-3 inhibition, BDNF upregulation, grey matter preservation

5 NAC

600 mg 

Morning, empty stomach 

Glutathione precursor — master antioxidant for brain tissue

Onset

Months — this is a long-term investment

Cycling

None required — all compounds safe for daily use

Monthly

$30

Level

beginner

### Expected Effects

Protection against age-related cognitive decline. May notice subtle improvements in clarity and resilience over months.

### Who It's For

Anyone over 30 wanting to protect their cognitive future, or those with family history of cognitive decline.

### What to Track

Annual cognitive assessments, brain fog frequency, overall mental clarity

### Cautions

Lithium Orotate at these micro-doses is very safe but inform your doctor. NAC on empty stomach for best absorption.

### Check compound interactions

Before starting any stack, verify there are no contraindications with medications or other supplements you take.

[Check the 5 compounds](/tools/interaction-checker?compounds=dha,lions-mane,creatine,lithium-orotate,nac)

## Frequently Asked Questions

What is the Neuroprotection stack? 

Five well-researched compounds that protect neurons, reduce oxidative stress, and support long-term cognitive resilience. Protocol includes 5 compounds: DHA, Lions Mane, Creatine, Lithium Orotate, NAC.

How much does the Neuroprotection stack cost per month? 

How long until I feel effects from the Neuroprotection stack? 

Do I need to cycle the Neuroprotection stack? 

Who is the Neuroprotection stack for? 

What should I track while running the Neuroprotection stack? 

What are the cautions with the Neuroprotection stack? 

## Related Stacks

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Mr. Happy Stack

The Reddit-famous mood & motivation protocol

$25/mo beginner 

](/stack/mr-happy-stack)[

Memory & Learning

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$35/mo beginner 

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Creativity & Flow

Divergent thinking and creative output

$38/mo intermediate 

](/stack/creativity)

### Want a personalized stack?

The Stack Builder matches you to the right protocol based on your goals, experience level, and medication sensitivities.

[Open the Stack Builder](/tools/nootropic-stack-builder)

[Back to all stacks](/tools/nootropic-stack-builder)

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