--- title: "AMPA + Racetam Study Set: Research Bench — BodyHackGuide" description: "one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use. 3 compounds, roles and evidence only, no dosing. Research" lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "WebPage", "name": "AMPA + Racetam Study Set: research bench", "description": "one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use.", "url": "https://www.bodyhackguide.co/stack/ampa-racetam-study-set", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/bhglogo.png" } } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is the AMPA + Racetam Study Set?", "acceptedAnswer": { "@type": "Answer", "text": "one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use. it covers 3 compounds: TAK-653, Nefiracetam, CDP-Choline. this is a reference page with no protocol on it." } }, { "@type": "Question", "name": "Is there human data behind the AMPA + Racetam Study Set?", "acceptedAnswer": { "@type": "Answer", "text": "human data: small phase 1 and 2 for TAK-653, small trials for nefiracetam, mixed for citicoline. TAK-653 has clean phase 1 safety data and an unpublished phase 2. nefiracetam has decades of animal work and small human trials that did not move their primary endpoints. citicoline has the most human data of the three and its biggest trial was null. nobody has studied the three together." } }, { "@type": "Question", "name": "Why does this page not list doses?", "acceptedAnswer": { "@type": "Answer", "text": "the research compounds on this bench are sold for laboratory research, not as supplements. BodyHackGuide publishes roles, evidence, overlap and conflicts for them, never amounts or schedules." } }, { "@type": "Question", "name": "What conflicts with the AMPA + Racetam Study Set?", "acceptedAnswer": { "@type": "Answer", "text": "TAK-653 with any other AMPA modulator (aniracetam, IDRA-21): avoid. TAK-653 with a seizure history or with drugs that lower the seizure threshold (tramadol, bupropion): avoid. nefiracetam with oxiracetam: they are not the same thing and nobody has tested them together. nefiracetam is cleared hepatically and there is no alcohol interaction study, which is itself a reason to be careful." } }, { "@type": "Question", "name": "Does BHG Labs sell these?", "acceptedAnswer": { "@type": "Answer", "text": "BHG Labs carries TAK-653, Nefiracetam as research-use-only products with a third-party COA on every lot. CDP-choline is a supplement. BHG Labs does not sell it; any supplement store does. BHG Labs and BodyHackGuide are commonly owned." } }, { "@type": "Question", "name": "Who is the AMPA + Racetam Study Set for?", "acceptedAnswer": { "@type": "Answer", "text": "experienced researchers who already keep a log. not a first stack." } } ] }, { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co" }, { "@type": "ListItem", "position": 2, "name": "Stacks", "item": "https://www.bodyhackguide.co/tools/nootropic-stack-builder" }, { "@type": "ListItem", "position": 3, "name": "AMPA + Racetam Study Set", "item": "https://www.bodyhackguide.co/stack/ampa-racetam-study-set" } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" }, { "@context": "https://schema.org", "@type": "WebPage", "name": "AMPA + Racetam Study Set: research bench", "description": "one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use.", "url": "https://www.bodyhackguide.co/stack/ampa-racetam-study-set", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/bhglogo.png" } } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is the AMPA + Racetam Study Set?", "acceptedAnswer": { "@type": "Answer", "text": "one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use. it covers 3 compounds: TAK-653, Nefiracetam, CDP-Choline. this is a reference page with no protocol on it." } }, { "@type": "Question", "name": "Is there human data behind the AMPA + Racetam Study Set?", "acceptedAnswer": { "@type": "Answer", "text": "human data: small phase 1 and 2 for TAK-653, small trials for nefiracetam, mixed for citicoline. TAK-653 has clean phase 1 safety data and an unpublished phase 2. nefiracetam has decades of animal work and small human trials that did not move their primary endpoints. citicoline has the most human data of the three and its biggest trial was null. nobody has studied the three together." } }, { "@type": "Question", "name": "Why does this page not list doses?", "acceptedAnswer": { "@type": "Answer", "text": "the research compounds on this bench are sold for laboratory research, not as supplements. BodyHackGuide publishes roles, evidence, overlap and conflicts for them, never amounts or schedules." } }, { "@type": "Question", "name": "What conflicts with the AMPA + Racetam Study Set?", "acceptedAnswer": { "@type": "Answer", "text": "TAK-653 with any other AMPA modulator (aniracetam, IDRA-21): avoid. TAK-653 with a seizure history or with drugs that lower the seizure threshold (tramadol, bupropion): avoid. nefiracetam with oxiracetam: they are not the same thing and nobody has tested them together. nefiracetam is cleared hepatically and there is no alcohol interaction study, which is itself a reason to be careful." } }, { "@type": "Question", "name": "Does BHG Labs sell these?", "acceptedAnswer": { "@type": "Answer", "text": "BHG Labs carries TAK-653, Nefiracetam as research-use-only products with a third-party COA on every lot. CDP-choline is a supplement. BHG Labs does not sell it; any supplement store does. BHG Labs and BodyHackGuide are commonly owned." } }, { "@type": "Question", "name": "Who is the AMPA + Racetam Study Set for?", "acceptedAnswer": { "@type": "Answer", "text": "experienced researchers who already keep a log. not a first stack." } } ] }, { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co" }, { "@type": "ListItem", "position": 2, "name": "Stacks", "item": "https://www.bodyhackguide.co/tools/nootropic-stack-builder" }, { "@type": "ListItem", "position": 3, "name": "AMPA + Racetam Study Set", "item": "https://www.bodyhackguide.co/stack/ampa-racetam-study-set" } ] }, { "@context": "https://schema.org", "@type": "Organization", "@id": "https://www.bodyhackguide.co#organization", "name": "BodyHackGuide", "alternateName": "BHG", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/logo.png", "width": 512, "height": 512 }, "description": "Evidence-based research reference for peptides and nootropics. 124+ compound profiles, interactive dosing calculators, real-time vendor pricing, and trust-scored vendor reviews scored on a public, reproducible methodology applied to every vendor. BodyHackGuide and BHG Labs share common ownership, and we earn a commission on purchases through our links.", "foundingDate": "2024", "founder": { "@id": "https://www.bodyhackguide.co/about#person" }, "sameAs": [ "https://x.com/bodyhackguide", "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher", "https://discord.gg/Mhq5UdRYBA" ], "knowsAbout": [ "Peptide research", "Nootropic research", "Biohacking", "Compound dosing", "Vendor transparency" ], "publishingPrinciples": "https://www.bodyhackguide.co/editorial-standards", "ethicsPolicy": "https://www.bodyhackguide.co/editorial-standards", "diversityPolicy": "https://www.bodyhackguide.co/editorial-standards" } ] --- [Skip to content](#main-content) ## Research Use Only This site is an **educational resource** for research compounds. We do **not endorse** human consumption of any compound. BodyHackGuide and **BHG Labs share common ownership**; we rank every vendor on the same public methodology, and we earn a commission on purchases through our links. By entering, you confirm you are **21 years of age or older** and agree to our [Terms](/terms) & [Privacy Policy](/privacy). I'm 21+ — Enter SiteLeave site [![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp)BodyHackGuide ](/) [Compare](/compare)[Wiki](/wiki)[Vendors](/vendors)[Deals](/deals)[Stacks](/stack-builder)[Nootropics](/nootropics)[Tools](/tools) Learn Community Search ⌘K [Sign In](/auth?returnTo=%2Fstack%2Fampa-racetam-study-set) 100K+ researchers trust BodyHackGuide — Join [r/BodyHackGuide](https://reddit.com/r/bodyhackguide) [Home](/)[Stack Builder](/tools/nootropic-stack-builder)AMPA + Racetam Study Set Research bench · research use only # AMPA + Racetam Study Set TAK-653 and nefiracetam, plus the choline people add underneath them no dosing on this page user reports: same day for TAK-653, weeks for nefiracetam advanced ## Overview one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use. ### Read this first everything on this page except CDP-choline is research use only. BHG Labs sells TAK-653 and nefiracetam as capsule research compounds with a third-party COA on every lot, not as supplements, and nothing here is a dosing instruction. if you have any seizure history, this set is not for you at all. a log with two changes in it cannot tell you which one did what. ## The bench: 3 compounds roles and evidence, not amounts. this page does not publish doses or schedules for research compounds. 1 TAK-653 [read the guide](/compound/tak-653) the AMPA positive allosteric modulator (osavampator). low intrinsic activity by design (about 5% in the functional assay), built for AMPA potentiation with less convulsive signal than the older ampakines showed in animals. evidence: the human data is Takeda phase 1 work under the name TAK-653 and one Neurocrine phase 2 (183 patients) under the name NBI-1065845. the phase 2 has posters and press releases but no peer-reviewed paper as of September 2026. watch for: the 419-fold safety margin people quote is a rat number. one rat convulsed at a single 100 mg/kg oral dose in Takeda's GLP study, and the margin is measured from that event. 2 Nefiracetam [read the guide](/compound/nefiracetam) the racetam. potentiates nicotinic and NMDA signalling in a bell-shaped way and touches GABA-A. the user reports describe weeks, not hours. evidence: decades of animal work and a handful of small human trials that did not move their primary endpoints. the Japanese development program was dropped in 2002 for lack of efficacy in dementia. watch for: dog studies showed testicular toxicity at 180 to 300 mg/kg. it is not interchangeable with oxiracetam. 3 CDP-Choline [read the guide](/compound/cdp-choline) the choline source. racetams raise acetylcholine turnover in animal work; citicoline is the best-studied choline in people. evidence: mixed human data. the big stroke trial (ICTUS) missed its endpoint and the attention studies are small. nefiracetam with citicoline has never been tested together in people. watch for: nausea and headache at the high end. it is a supplement, not a research chemical. Form capsules, as sold Human data small phase 1 and 2 for TAK-653, small trials for nefiracetam, mixed for citicoline BHG Labs carries 2 of 3 Level advanced ### Why these together TAK-653 and nefiracetam pull on different parts of glutamate signalling. TAK-653 potentiates AMPA receptors directly. nefiracetam works upstream through nicotinic and NMDA potentiation, and the user reports describe weeks before anything changes. citicoline sits underneath both for that reason. the common report is that headaches on a racetam ease when choline goes in. nobody has measured it. ### Overlap nefiracetam is not an AMPA modulator, so this pairing is not the doubling-up problem. the overlap to watch is stimulation. reports put TAK-653 next to heavy caffeine as wired rather than sharp. ### Conflicts TAK-653 with any other AMPA modulator (aniracetam, IDRA-21): avoid. TAK-653 with a seizure history or with drugs that lower the seizure threshold (tramadol, bupropion): avoid. nefiracetam with oxiracetam: they are not the same thing and nobody has tested them together. nefiracetam is cleared hepatically and there is no alcohol interaction study, which is itself a reason to be careful. ### What the evidence actually is TAK-653 has clean phase 1 safety data and an unpublished phase 2. nefiracetam has decades of animal work and small human trials that did not move their primary endpoints. citicoline has the most human data of the three and its biggest trial was null. nobody has studied the three together. ### What people report people describe sharper recall on TAK-653 days and a slower change from nefiracetam over weeks. that is user report, not trial data. ### Who It's For experienced researchers who already keep a log. not a first stack. ### What to Track recall on a fixed test, sleep, headache days, irritability ## Sourced at BHG Labs Ownership disclosure: BHG Labs and BodyHackGuide are commonly owned. When you buy from BHG Labs, the team behind this site benefits, so read the evidence sections above with that in mind. Third-party COA on every lot. Research use only. Code REDDIT takes 10% off at checkout. [ TAK-653 $79.99 · lot-numbered · COA on the lot ](https://bhglabs.co/product/tak-653/?ref=zmgqyxku&coupon=BHG20)[ Nefiracetam $44.99 · lot-numbered · COA on the lot ](https://bhglabs.co/product/nefiracetam/?ref=zmgqyxku&coupon=BHG20) CDP-choline is a supplement. BHG Labs does not sell it; any supplement store does. ### Read the compound guides [TAK-653](/compound/tak-653) [Nefiracetam](/compound/nefiracetam) [CDP-Choline](/compound/cdp-choline) ## Frequently Asked Questions What is the AMPA + Racetam Study Set? one AMPA modulator, one racetam, one choline source. it does not tell you how much of anything to use. it covers 3 compounds: TAK-653, Nefiracetam, CDP-Choline. this is a reference page with no protocol on it. Is there human data behind the AMPA + Racetam Study Set? Why does this page not list doses? What conflicts with the AMPA + Racetam Study Set? Does BHG Labs sell these? Who is the AMPA + Racetam Study Set for? ## Related Stacks [ Memory & Learning Optimize encoding, retention, and recall $35/mo beginner ](/stack/memory-learning)[ Creativity & Flow Divergent thinking and creative output $38/mo intermediate ](/stack/creativity)[ Nasal Peptide Bench Selank and Adamax, with Semax as the comparison point research bench advanced ](/stack/nasal-peptide-bench) ### Want a personalized stack? The Stack Builder matches you to the right protocol based on your goals, experience level, and medication sensitivities. [Open the Stack Builder](/tools/nootropic-stack-builder) [Back to all stacks](/tools/nootropic-stack-builder) Was this page helpful? Yes No ![BodyHackGuide](/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub — compound pricing, brain health protocols, dosing tools, and vendor reviews. 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