--- title: "YK-11 Dosage Guide [2026] | BodyHackGuide" url: https://www.bodyhackguide.co/guides/dosage/yk-11 description: "Complete YK-11 dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Performance Preclinical # YK-11 Dosage Guide: Protocols, Calculator & Safety Everything you need to know about YK-11 dosing: protocols, safety, and where to buy. Half-Life Not established. In a human elimination study using deuterium-labeled YK-11, no intact parent compound was seen in urine; unconjugated metabolites disappeared within 24 hours and glucuronidated and sulfated metabolites remained traceable beyond 48 hours (PMID: 30379415) ## Administration Routes Oral Dosage Calculator Calculate exact dosing for YK-11. https://www.bodyhackguide.co/tools/dosage Dosing data for YK-11 is being researched. Check the compound page (https://www.bodyhackguide.co/compound/yk-11) for the latest information. ## Side Effects & Safety No human safety data. Rat studies report harm to the brain: five weeks of YK-11 in male Wistar rats increased oxidative stress and impaired all measured markers of mitochondrial function in the hippocampus, and combining it with swimming exercise did not reverse those changes (PMID: 37468001). A second rat study reported impaired aversive memory consolidation, downregulation of BDNF, TrkB and CREB signaling, higher interleukin 1 beta and interleukin 6, lower interleukin 10, and activation of a p38 MAPK and caspase 3 apoptotic cascade in the hippocampus (PMID: 38521455). Because YK-11 is an androgen receptor agonist, the class effects documented for other SARMs, including drug-induced liver injury and suppression of endogenous testosterone, are plausible but have not been measured for this compound (PMID: 37218811). Contraindications No sourced clinical contraindications exist because there are no human studies. Mechanism-based: as an androgen receptor agonist it should be avoided in pregnancy because of the risk of virilizing a female fetus, and in anyone with known or suspected prostate cancer. The rat neurotoxicity findings are a mechanism-based reason for caution in general (PMID: 37468001, PMID: 38521455). Athletes in tested sport must avoid it, since it is prohibited at all times (PMID: 28137616). Check interactions with the Interaction Checker → (https://www.bodyhackguide.co/tools/interaction-checker) ## Frequently Asked Questions What is the recommended YK-11 dosage? Dosage for YK-11 varies by protocol. Consult a qualified healthcare provider. How often should I take YK-11? Administration frequency depends on the specific protocol. Consult current research literature. Does YK-11 need to be cycled? Cycling requirements depend on the protocol. Follow established research guidelines. What are YK-11 side effects? Where can I buy YK-11? Compare 2 listings from 1 vendor on our price comparison page, starting from $79.99. YK-11 Full Profile Research data, mechanisms, and pricing https://www.bodyhackguide.co/compound/yk-11 Interaction Checker Check drug & compound interactions https://www.bodyhackguide.co/tools/interaction-checker ## Related Dosage Guides All Guides (https://www.bodyhackguide.co/guides) ### ITPP Performance · Dosage Guide https://www.bodyhackguide.co/guides/dosage/itpp ### PEG-MGF Performance · Dosage Guide https://www.bodyhackguide.co/guides/dosage/peg-mgf ### SLU-PP-332 Performance · Dosage Guide https://www.bodyhackguide.co/guides/dosage/slu-pp-332 Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) ## Structured data ```json [ { "@context": "https://schema.org", "@type": "Article", "headline": "YK-11 Dosage Guide [2026]", "description": "Complete YK-11 dosage guide with protocols, calculator, safety info, and where to buy. 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Consult a qualified healthcare provider." } }, { "@type": "Question", "name": "How often should I take YK-11?", "acceptedAnswer": { "@type": "Answer", "text": "Administration frequency depends on the specific protocol. Consult current research literature." } }, { "@type": "Question", "name": "Does YK-11 need to be cycled?", "acceptedAnswer": { "@type": "Answer", "text": "Cycling requirements depend on the protocol. Follow established research guidelines." } }, { "@type": "Question", "name": "What are YK-11 side effects?", "acceptedAnswer": { "@type": "Answer", "text": "No human safety data. Rat studies report harm to the brain: five weeks of YK-11 in male Wistar rats increased oxidative stress and impaired all measured markers of mitochondrial function in the hippocampus, and combining it with swimming exercise did not reverse those changes (PMID: 37468001). A second rat study reported impaired aversive memory consolidation, downregulation of BDNF, TrkB and CREB signaling, higher interleukin 1 beta and interleukin 6, lower interleukin 10, and activation of a p38 MAPK and caspase 3 apoptotic cascade in the hippocampus (PMID: 38521455). Because YK-11 is an androgen receptor agonist, the class effects documented for other SARMs, including drug-induced liver injury and suppression of endogenous testosterone, are plausible but have not been measured for this compound (PMID: 37218811)." } }, { "@type": "Question", "name": "Where can I buy YK-11?", "acceptedAnswer": { "@type": "Answer", "text": "Compare 2 listings from 1 vendor on our price comparison page, starting from $79.99." } } ] }, { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Guides", "item": "https://www.bodyhackguide.co/guides" }, { "@type": "ListItem", "position": 3, "name": "Dosage Guides", "item": "https://www.bodyhackguide.co/guides" }, { "@type": "ListItem", "position": 4, "name": "YK-11 Dosage", "item": "https://www.bodyhackguide.co/guides/dosage/yk-11" } ] } ] ```