--- title: "Sunifiram Dosage Guide [2026] | BodyHackGuide" url: https://www.bodyhackguide.co/guides/dosage/sunifiram description: "Complete Sunifiram (DM-235) dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Nootropics Preclinical # Sunifiram (DM-235) Dosage Guide: Protocols, Calculator & Safety Everything you need to know about Sunifiram (DM-235) dosing: protocols, safety, and where to buy. Half-Life Not established. No pharmacokinetic study in humans or animals has been published, and the group that discovered the compound stated that its long-term toxicity was unknown (PMID: 25831025). ## Administration Routes Oral Dosage Calculator Calculate exact dosing for Sunifiram (DM-235). https://www.bodyhackguide.co/tools/dosage Dosing data for Sunifiram (DM-235) is being researched. Check the compound page (https://www.bodyhackguide.co/compound/sunifiram) for the latest information. ## Side Effects & Safety No human safety data exist. No clinical trial, case series, pharmacovigilance report or pharmacokinetic study has been published for sunifiram in humans, and the group that discovered it stated in 2015 that its long-term toxicity was unknown while it was already being sold online (PMID: 25831025). In the mouse and rat behavioral work, the compound did not impair motor coordination on the rotarod and did not change spontaneous motility or inspection activity at the doses that reversed amnesia (PMID: 12070754). The absence of reported harm here reflects the absence of anyone looking, not a demonstration of safety. Contraindications None established, because no human study exists. Mechanism-based cautions: sunifiram acts at the glycine site of the NMDA receptor and enhances long-term potentiation with a bell-shaped concentration-response curve in mouse hippocampal slices, so higher exposure is not simply more of the same effect (PMID: 23733502). Compounds that increase NMDA and AMPA receptor signaling carry a theoretical excitotoxicity and seizure risk, which is relevant to anyone with a seizure disorder or recent brain injury. No reproductive toxicity, genotoxicity, repeat-dose toxicity or drug interaction data have been published in any species. Check interactions with the Interaction Checker → (https://www.bodyhackguide.co/tools/interaction-checker) ## Frequently Asked Questions What is the recommended Sunifiram (DM-235) dosage? Dosage for Sunifiram (DM-235) varies by protocol. Consult a qualified healthcare provider. How often should I take Sunifiram (DM-235)? Administration frequency depends on the specific protocol. Consult current research literature. Does Sunifiram (DM-235) need to be cycled? Cycling requirements depend on the protocol. Follow established research guidelines. What are Sunifiram (DM-235) side effects? Where can I buy Sunifiram (DM-235)? Compare 2 listings from 1 vendor on our price comparison page, starting from $59.99. Sunifiram (DM-235) Full Profile Research data, mechanisms, and pricing https://www.bodyhackguide.co/compound/sunifiram Interaction Checker Check drug & compound interactions https://www.bodyhackguide.co/tools/interaction-checker ## Related Dosage Guides All Guides (https://www.bodyhackguide.co/guides) ### 9-Me-BC (9-Methyl-β-carboline) Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/9-mbc ### Dihexa Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/dihexa ### Kavain Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/kavain ### Methylene Blue Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/methylene-blue Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) ## Structured data ```json [ { "@context": "https://schema.org", "@type": "Article", "headline": "Sunifiram Dosage Guide [2026]", "description": "Complete Sunifiram (DM-235) dosage guide with protocols, calculator, safety info, and where to buy. 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