--- title: "Sobetirome Dosage Guide [2026] | BodyHackGuide" url: https://www.bodyhackguide.co/guides/dosage/sobetirome description: "Complete Sobetirome (GC-1) dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Metabolic Discontinued # Sobetirome (GC-1) Dosage Guide: Protocols, Calculator & Safety Everything you need to know about Sobetirome (GC-1) dosing: protocols, safety, and where to buy. Half-Life Not established in humans; no peer-reviewed human pharmacokinetic study has been published, and the phase 1 program results were not reported in the peer-reviewed literature (PMID: 19002578) ## Administration Routes Oral Dosage Calculator Calculate exact dosing for Sobetirome (GC-1). https://www.bodyhackguide.co/tools/dosage Dosing data for Sobetirome (GC-1) is being researched. Check the compound page (https://www.bodyhackguide.co/compound/sobetirome) for the latest information. ## Side Effects & Safety No peer-reviewed human safety data. The animal record contains a specific warning: GC-1 acted as a strong mitogen in rats, inducing hepatocyte proliferation in the absence of tissue injury and massive pancreatic acinar cell proliferation (PMID: 16574785). Thyroid receptor beta agonism as a class suppresses thyroid stimulating hormone, which was demonstrated in the rat dose-response work (PMID: 10965874). The cardiac sparing seen in rats and monkeys is relative, not absolute; tachycardia appeared at higher exposure in rats (PMID: 14701670). Contraindications Mechanism-based, since no human trial has defined contraindications. Thyroid hormone receptor agonism is inappropriate for anyone with existing hyperthyroidism, atrial fibrillation or unstable coronary disease, and it suppresses thyroid stimulating hormone and disturbs thyroid function testing (PMID: 10965874). The rat liver and pancreas proliferation findings argue against use by anyone with liver disease or pancreatic disease (PMID: 16574785). No human pregnancy, lactation or pediatric data exist. Anyone taking levothyroxine or antithyroid medication would have their treatment monitoring confounded. Check interactions with the Interaction Checker → (https://www.bodyhackguide.co/tools/interaction-checker) ## Frequently Asked Questions What is the recommended Sobetirome (GC-1) dosage? Dosage for Sobetirome (GC-1) varies by protocol. Consult a qualified healthcare provider. How often should I take Sobetirome (GC-1)? Administration frequency depends on the specific protocol. Consult current research literature. Does Sobetirome (GC-1) need to be cycled? Cycling requirements depend on the protocol. Follow established research guidelines. What are Sobetirome (GC-1) side effects? Where can I buy Sobetirome (GC-1)? Compare 1 listings from 1 vendor on our price comparison page, starting from $149.99. Sobetirome (GC-1) Full Profile Research data, mechanisms, and pricing https://www.bodyhackguide.co/compound/sobetirome Interaction Checker Check drug & compound interactions https://www.bodyhackguide.co/tools/interaction-checker Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) ## Structured data ```json [ { "@context": "https://schema.org", "@type": "Article", "headline": "Sobetirome Dosage Guide [2026]", "description": "Complete Sobetirome (GC-1) dosage guide with protocols, calculator, safety info, and where to buy. 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