---
title: "GB-115 Dosage Guide [2026] | BodyHackGuide"
url: https://www.bodyhackguide.co/guides/dosage/gb-115
description: "Complete GB-115 dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026."
lang: en
---

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Nootropics Approved (Russia)

# GB-115 Dosage Guide: Protocols, Calculator & Safety

Everything you need to know about GB-115 dosing: protocols, safety, and where to buy.

Half-Life

Not established in humans; the published rat pharmacokinetic work reported an absolute oral bioavailability of 4.65 percent for the crystalline substance and did not report a terminal half-life (PMID: 18457023)

## Administration Routes

Oral Intraperitoneal injection (animal studies) Aerosol spray (form sold on the research chemical market)

### Quick Reconstitution Calculator

Calculate syringe units instantly

Syringe Draw

10.0 units

2500 mcg/ml · 0.100 ml draw

Full Tool (https://www.bodyhackguide.co/tools/reconstitution)

For laboratory research use only. This tool performs reconstitution math (concentration and syringe-unit conversion) and is not dosing guidance for humans or animals.

Dosing data for GB-115 is being researched. Check the compound page (https://www.bodyhackguide.co/compound/gb-115) for the latest information.

## Side Effects & Safety

Preclinical safety work found no deaths after single oral administration at up to 6000 mg/kg in mice and 3500 mg/kg in rats, and no irreversible organ changes after six months of oral administration in male and female rats and rabbits; the compound showed no allergenic, immunotoxic or mutagenic activity and did not affect reproduction or antenatal and postnatal development of offspring, though it suppressed the inflammatory response to concanavalin A at the higher level tested (PMID: 20726348). Rats given the compound daily for 30 days showed no anxiety, aggression or convulsive signs on withdrawal, in contrast to diazepam (PMID: 21899090). In the single published clinical study the drug was described as safe and well tolerated, but that report provides no adverse event table in its abstract (PMID: 31626171). The Russian label for Rankvilon lists irritability, headache, nausea, diarrhea, drowsiness and sleep disturbance as adverse reactions of unknown frequency.

Contraindications

None established in humans. Mechanism-based: the compound blocks central cholecystokinin receptors (PMID: 23113301), so concurrent drugs acting on that system are an untested interaction. It potentiated morphine analgesia in mice through supraspinal opioid mechanisms (PMID: 18239806), which makes combination with opioids a mechanism-based concern. It also has immunomodulating activity in mice, stimulating macrophage phagocytosis and the humoral immune response (PMID: 19145294), and suppressed an experimental inflammatory response in rodents (PMID: 22235394), neither of which has been characterized in people.

Check interactions with the Interaction Checker → (https://www.bodyhackguide.co/tools/interaction-checker)

## Frequently Asked Questions

What is the recommended GB-115 dosage?

Dosage for GB-115 varies by protocol. Consult a qualified healthcare provider.

How often should I take GB-115?

Administration frequency depends on the specific protocol. Consult current research literature.

Does GB-115 need to be cycled?

Cycling requirements depend on the protocol. Follow established research guidelines.

What are GB-115 side effects?

Where can I buy GB-115?

Compare 1 listings from 1 vendor on our price comparison page, starting from $59.99.

GB-115 Full Profile

Research data, mechanisms, and pricing
https://www.bodyhackguide.co/compound/gb-115

Interaction Checker

Check drug & compound interactions
https://www.bodyhackguide.co/tools/interaction-checker

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All Guides (https://www.bodyhackguide.co/guides)

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