--- title: "Fladrafinil Dosage Guide [2026] | BodyHackGuide" url: https://www.bodyhackguide.co/guides/dosage/fladrafinil description: "Complete Fladrafinil (CRL-40,941) dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Nootropics Preclinical # Fladrafinil (CRL-40,941) Dosage Guide: Protocols, Calculator & Safety Everything you need to know about Fladrafinil (CRL-40,941) dosing: protocols, safety, and where to buy. Half-Life Not established in humans; after a single 20 mg oral dose in six volunteers, urinary fladrafinil peaked at 2 to 4 h and stayed detectable for up to 12 h, while the metabolite flmodafinil was detectable for about 8 days and the acid and sulfone metabolites for about two weeks (PMID: 42210629) ## Administration Routes Oral Dosage Calculator Calculate exact dosing for Fladrafinil (CRL-40,941). https://www.bodyhackguide.co/tools/dosage Dosing data for Fladrafinil (CRL-40,941) is being researched. Check the compound page (https://www.bodyhackguide.co/compound/fladrafinil) for the latest information. ## Side Effects & Safety No safety trial has been published. The only human administration study was a six-person single-dose pharmacokinetic study run for doping-control purposes, and it did not report adverse events (PMID: 42210629). Products bought from supplement sellers for that study were mislabelled for content, one containing nearly twice the stated concentration (PMID: 42210629), so what reaches a buyer may not match the label. Adverse effects reported for the parent compound modafinil cannot be assumed to transfer unchanged to a difluorinated analog. Contraindications Mechanism-based: fladrafinil is converted to a compound of the modafinil class, and modafinil occupies dopamine transporters and raises brain dopamine in humans, an effect the investigators linked to abuse potential in vulnerable people (PMID: 19293415). Athletes subject to anti-doping testing should treat it as prohibited in competition (PMID: 42210629). No pregnancy, hepatic or cardiac safety data exist for fladrafinil in any species. Check interactions with the Interaction Checker → (https://www.bodyhackguide.co/tools/interaction-checker) ## Frequently Asked Questions What is the recommended Fladrafinil (CRL-40,941) dosage? Dosage for Fladrafinil (CRL-40,941) varies by protocol. Consult a qualified healthcare provider. How often should I take Fladrafinil (CRL-40,941)? Administration frequency depends on the specific protocol. Consult current research literature. Does Fladrafinil (CRL-40,941) need to be cycled? Cycling requirements depend on the protocol. Follow established research guidelines. What are Fladrafinil (CRL-40,941) side effects? Where can I buy Fladrafinil (CRL-40,941)? Compare 1 listings from 1 vendor on our price comparison page, starting from $74.99. Fladrafinil (CRL-40,941) Full Profile Research data, mechanisms, and pricing https://www.bodyhackguide.co/compound/fladrafinil Interaction Checker Check drug & compound interactions https://www.bodyhackguide.co/tools/interaction-checker ## Related Dosage Guides All Guides (https://www.bodyhackguide.co/guides) ### 9-Me-BC (9-Methyl-β-carboline) Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/9-mbc ### Dihexa Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/dihexa ### Kavain Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/kavain ### Methylene Blue Nootropics · Dosage Guide https://www.bodyhackguide.co/guides/dosage/methylene-blue Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) ## Structured data ```json [ { "@context": "https://schema.org", "@type": "Article", "headline": "Fladrafinil Dosage Guide [2026]", "description": "Complete Fladrafinil (CRL-40,941) dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026.", "author": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "reviewedBy": { "@type": "Person", "name": "BioChonch", "url": "https://www.bodyhackguide.co/about", "jobTitle": "Founder & Lead Researcher", "sameAs": [ "https://reddit.com/r/BodyHackGuide", "https://reddit.com/r/BrainHackGuide", "https://reddit.com/r/Biohackingher" ], "worksFor": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co" } }, "publisher": { "@type": "Organization", "name": "BodyHackGuide", "url": "https://www.bodyhackguide.co", "logo": { "@type": "ImageObject", "url": "https://www.bodyhackguide.co/bhglogo.png" } } }, { "@context": "https://schema.org", "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "What is the recommended Fladrafinil (CRL-40,941) dosage?", "acceptedAnswer": { "@type": "Answer", "text": "Dosage for Fladrafinil (CRL-40,941) varies by protocol. Consult a qualified healthcare provider." } }, { "@type": "Question", "name": "How often should I take Fladrafinil (CRL-40,941)?", "acceptedAnswer": { "@type": "Answer", "text": "Administration frequency depends on the specific protocol. Consult current research literature." } }, { "@type": "Question", "name": "Does Fladrafinil (CRL-40,941) need to be cycled?", "acceptedAnswer": { "@type": "Answer", "text": "Cycling requirements depend on the protocol. Follow established research guidelines." } }, { "@type": "Question", "name": "What are Fladrafinil (CRL-40,941) side effects?", "acceptedAnswer": { "@type": "Answer", "text": "No safety trial has been published. The only human administration study was a six-person single-dose pharmacokinetic study run for doping-control purposes, and it did not report adverse events (PMID: 42210629). Products bought from supplement sellers for that study were mislabelled for content, one containing nearly twice the stated concentration (PMID: 42210629), so what reaches a buyer may not match the label. Adverse effects reported for the parent compound modafinil cannot be assumed to transfer unchanged to a difluorinated analog." } }, { "@type": "Question", "name": "Where can I buy Fladrafinil (CRL-40,941)?", "acceptedAnswer": { "@type": "Answer", "text": "Compare 1 listings from 1 vendor on our price comparison page, starting from $74.99." } } ] }, { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bodyhackguide.co/" }, { "@type": "ListItem", "position": 2, "name": "Guides", "item": "https://www.bodyhackguide.co/guides" }, { "@type": "ListItem", "position": 3, "name": "Dosage Guides", "item": "https://www.bodyhackguide.co/guides" }, { "@type": "ListItem", "position": 4, "name": "Fladrafinil (CRL-40,941) Dosage", "item": "https://www.bodyhackguide.co/guides/dosage/fladrafinil" } ] } ] ```