--- title: "AICAR Dosage Guide [2026] | BodyHackGuide" url: https://www.bodyhackguide.co/guides/dosage/aicar description: "Complete AICAR (acadesine) dosage guide with protocols, calculator, safety info, and where to buy. Updated for 2026." lang: en --- Skip to content Compare notes on r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Compare notes with other researchers. Join r/BodyHackGuide (https://reddit.com/r/bodyhackguide) Metabolic Phase 3 # AICAR (acadesine) Dosage Guide: Protocols, Calculator & Safety Everything you need to know about AICAR (acadesine) dosing: protocols, safety, and where to buy. Half-Life Intact acadesine was measurable in plasma for only about 2 hours after a short intravenous infusion in four healthy men, with total plasma clearance of 2.2 L/h/kg and negligible protein binding; radiolabeled drug-derived material had an apparent terminal half-life of about one week, reflecting metabolites rather than parent compound (PMID: 8227467) ## Administration Routes Intravenous infusion (human trials) Intraperitoneal injection (rodent studies) ### Quick Reconstitution Calculator Calculate syringe units instantly Syringe Draw 10.0 units 2500 mcg/ml · 0.100 ml draw Full Tool (https://www.bodyhackguide.co/tools/reconstitution) For laboratory research use only. This tool performs reconstitution math (concentration and syringe-unit conversion) and is not dosing guidance for humans or animals. Dosing data for AICAR (acadesine) is being researched. Check the compound page (https://www.bodyhackguide.co/compound/aicar) for the latest information. ## Side Effects & Safety In the leukemia phase I/II study, intravenous acadesine commonly caused hyperuricemia, along with transient anemia and thrombocytopenia, renal impairment and infusion-related hypotension; the hyperuricemia was managed with allopurinol prophylaxis (PMID: 23228986). Uric acid is the major human metabolite, which explains the urate load (PMID: 8227467). The 3080-patient cardiac surgery trial did not report an excess of harm but also showed no benefit (PMID: 22782417). No safety data exist for oral use or for the powder sold to consumers. Contraindications Mechanism-based: because acadesine is metabolized mainly to uric acid in humans, it is a poor fit for anyone with gout, hyperuricemia or impaired kidney function (PMID: 8227467; PMID: 23228986). Infusion-related hypotension was reported in the leukemia study, so people on blood pressure lowering therapy face an additive effect. Prohibited in tested sport under WADA section S4.4. No pregnancy, lactation or pediatric safety data exist. Check interactions with the Interaction Checker → (https://www.bodyhackguide.co/tools/interaction-checker) ## Frequently Asked Questions What is the recommended AICAR (acadesine) dosage? Dosage for AICAR (acadesine) varies by protocol. Consult a qualified healthcare provider. How often should I take AICAR (acadesine)? Administration frequency depends on the specific protocol. Consult current research literature. Does AICAR (acadesine) need to be cycled? Cycling requirements depend on the protocol. Follow established research guidelines. What are AICAR (acadesine) side effects? Where can I buy AICAR (acadesine)? Compare 1 listings from 1 vendor on our price comparison page, starting from $49.99. AICAR (acadesine) Full Profile Research data, mechanisms, and pricing https://www.bodyhackguide.co/compound/aicar Interaction Checker Check drug & compound interactions https://www.bodyhackguide.co/tools/interaction-checker Free 2026 Peptide Cheat Sheet (PDF) 38 compounds and blends: vial sizes, BAC water volumes, dosing ranges and bloodwork markers. Download Free (https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download) Image: BodyHackGuide (https://www.bodyhackguide.co/assets/bodyhackguide-logo-DOzZNUyh.webp) ### BodyHackGuide Your biohacking research hub: compound pricing, brain health protocols, dosing tools, and vendor reviews. support@bodyhackguide.co Join our Discord: https://discord.gg/Mhq5UdRYBA r/BodyHackGuide on Reddit: https://reddit.com/r/BodyHackGuide #### Explore - Compare prices: https://www.bodyhackguide.co/compare - Vendors: https://www.bodyhackguide.co/vendors - Deals: https://www.bodyhackguide.co/deals - Coupons: https://www.bodyhackguide.co/coupons - Nootropics: https://www.bodyhackguide.co/nootropics - Brain health: https://www.bodyhackguide.co/brain-health - Blog: https://www.bodyhackguide.co/blog - Guides: https://www.bodyhackguide.co/guides #### Tools - Reconstitution: https://www.bodyhackguide.co/tools/reconstitution - Half-life visualizer: https://www.bodyhackguide.co/tools/halflife - COA reader: https://www.bodyhackguide.co/tools/coa - Cost calculator: https://www.bodyhackguide.co/tools/cost-calculator - Stack builder: https://www.bodyhackguide.co/stack-builder - All tools: https://www.bodyhackguide.co/tools #### Trust & vendors - Vendor directory: https://www.bodyhackguide.co/vendors - Trust scorecard: https://www.bodyhackguide.co/vendors/scorecard - Vendor trust badge: https://www.bodyhackguide.co/vendors/get-vetted - Scoring methodology: https://www.bodyhackguide.co/vendors/methodology - Peptide cheat sheet: https://www.bodyhackguide.co/guides/peptide-cheat-sheet-download #### Company - About: https://www.bodyhackguide.co/about - Affiliate disclosure: https://www.bodyhackguide.co/affiliate-disclosure - Editorial standards: https://www.bodyhackguide.co/editorial-standards - Creators: https://www.bodyhackguide.co/creators - Coaches: https://www.bodyhackguide.co/coaches - 1-on-1 coaching: https://www.bodyhackguide.co/coaching - Privacy: https://www.bodyhackguide.co/privacy - Terms: https://www.bodyhackguide.co/terms - Full site directory: https://www.bodyhackguide.co/site-directory **Affiliate Disclosure:** We rank every vendor on the same public, reproducible methodology (https://www.bodyhackguide.co/vendors/methodology), and we earn a commission from purchases made through some of our links at no extra cost to you. Full details in our affiliate disclosure (https://www.bodyhackguide.co/affiliate-disclosure). **Research Disclaimer:** All compounds listed are for laboratory and research purposes only. Not for human consumption. This site does not sell or ship any products. Always consult a qualified healthcare professional and comply with local regulations. © 2026 BodyHackGuide. All rights reserved. · Terms (https://www.bodyhackguide.co/terms) · Privacy (https://www.bodyhackguide.co/privacy) ## Structured data ```json [ { "@context": "https://schema.org", "@type": "Article", "headline": "AICAR Dosage Guide [2026]", "description": "Complete AICAR (acadesine) dosage guide with protocols, calculator, safety info, and where to buy. 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